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Found 4 clinical trials
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL Mixed Phenotype Acute Leukemia and B-LLy

This phase III trial studies whether inotuzumab ozogamicin added to post-induction chemotherapy for patients with High-Risk B-cell Acute Lymphoblastic Leukemia (B-ALL) improves outcomes. This trial also studies the outcomes of patients with mixed phenotype acute leukemia (MPAL), and B-lymphoblastic lymphoma (B-LLy) when treated with ALL therapy without inotuzumab ozogamicin. Inotuzumab …

cyclophosphamide
lymphoblastic lymphoma
cytarabine
white blood cell count
leucovorin
  • 42 views
  • 27 Mar, 2021
  • 113 locations
Different Therapies in Treating Infants With Newly Diagnosed Acute Leukemia

RATIONALE: Giving chemotherapy before a donor stem cell transplant helps stop the growth of cancer cells. It also helps stop the patient's immune system from rejecting the donor's stem cells. When the healthy stem cells from a donor are infused into the patient they may help the patient's bone marrow …

cyclophosphamide
bone marrow transplant
cytarabine
white blood cell count
umbilical cord blood transplantation
  • 12 views
  • 23 Jan, 2021
  • 5 locations
A Treatment Study Protocol for Participants 1-45 Years With Acute Lymphoblastic Leukaemia

ALLTogether collects the experience of previously successful treatment of children and young adults, with ALL from a number of well-renowned study groups into a new master protocol, which is both a comprehensive system for stratification and treatment of ALL in this age-group as well as the basis for several randomised …

vincristine
doxorubicin
inotuzumab
dexamethasone
imatinib
  • 27 views
  • 27 Jan, 2021
  • 102 locations
Treatment of Newly Diagnosed High Risk Acute Lymphoblastic Leukemia in Children

Treatment of pediatric acute lymphoblastic leukemia (ALL) has advanced and the overall survival exceeds 80% nowadays. However the overall survival of high risk ALL remains 75-90%, thus recent studies focus on treatment intensification according to the risk group. According to the previous reports, we designed a multicenter prospective trial for …

childhood all
lymphoid leukemia
methotrexate
blood cell count
b-cell acute lymphoblastic leukemia
  • 8 views
  • 21 Jan, 2021