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Found 113 clinical trials
QuantiFERON-CMV Test in a Prediction for Colic Cytomegalovirus Reactivation During Ulcerative Colitis (RECOHFERRON)

CytoMegaloVirus (CMV) infection impairs evolution of Ulcerative Colitis (UC) leading to more severe and resistant to immunosuppressive therapies flare-up. CytoMegaloVirus (CMV) reactivation is

immunosuppressive agents
immunosuppression
colitis
  • 6 views
  • 01 May, 2022
  • 3 locations
Triplex Vaccine in Preventing CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplantation

This phase II trial studies how well Triplex vaccine works in preventing cytomegalovirus (CMV) infection in patients undergoing a hematopoietic stem cell transplantation. CMV is a virus that may

cancer
chronic lymphocytic leukemia
immunosuppressant
myeloid leukemia
ct scan
  • 13 views
  • 07 Oct, 2022
  • 1 location
Treatment of CMV Infections With Viral-Specific T Cells Against CMV in Pediatric and Adult Immunocompromised Patients or Recipients of Allogeneic Stem Cell Transplantation

Cytomegalovirus (CMV) infections with virus-specific, antigen-selected T-cells. CMV-specific T-cells will be isolated from donor leukapheresis products using the CliniMACS® Prodigy. Prior studies on transfer of

viremia
colitis
antiviral drugs
pneumonia
valganciclovir
  • 41 views
  • 23 Oct, 2022
  • 1 location
Prenatal Treatment of Congenital Cytomegalovirus Infection With Letermovir Randomized Against Valaciclovir - STEP 1 (CYMEVAL3-STEP1)

In the model of the perfused cotyledon, Letermovir crosses the placenta to reach appropriate fetal concentration. The cotyledon model can only be performed in the third trimester placenta. Although it is probable that the transplacental passage in the second trimester is in the same range than the one found in …

Accepts healthy volunteers
  • 0 views
  • 27 Nov, 2021
  • 1 location
A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of Cytomegalovirus (CMV) Vaccine mRNA-1647

cytomegalovirus (CMV)-seronegative and CMV-seropositive Japanese adults 18 to 40 years of age in the United States.

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 3 locations
Trial of Third Party Donor Derived CMVpp65 Specific T-cells for The Treatment of CMV Infection or Persistent CMV Viremia After Allogeneic Hematopoietic Stem Cell Transplantation

The purpose of this study is to see how well transfusions of T-cells work in treating CMV. Tcells are a type of white blood cell that helps protect the body from infection. A transfusion is the

retinitis
viremia
colitis
antiviral drugs
pneumonia
  • 35 views
  • 04 Oct, 2022
  • 1 location
ANTIVIRAL TREATMENT OF CYTOMEGALOVIRUS IN DEPRESSION

This study aims to determine whether treatment of CMV positive (CMV+) individuals with major depressive disorder (MDD) with valganciclovir (VGCV) alters neural circuitry, reduces inflammation

  • 0 views
  • 26 Mar, 2022
  • 1 location
PEP-CMV in Recurrent MEdulloblastoma/Malignant Glioma (PRiME)

The primary goal of this prospective clinical trial is to evaluate the safety of PEP-CMV in patients with recurrent medulloblastoma and malignant glioma. Patients with histologically-proven

cancer
brain mri
medulloblastoma
neutrophil count
recurrent tumor
  • 22 views
  • 19 Jun, 2022
  • 1 location
Letermovir for CMV Prevention After Lung Transplantation

This is an interventional, open-label, single center, pilot study with historical controls to test the efficacy of letermovir (LET) for the prevention of CMV infection and disease in adult lung

  • 1 views
  • 27 May, 2022
  • 1 location
Multi-antigen CMV-Modified Vaccinia Ankara Vaccine in Treating Pediatric Patients With Positive Cytomegalovirus Undergoing Donor Stem Cell Transplant

This phase I/II trial studies the side effects and best dose of multi-antigen cytomegalovirus (CMV)-modified vaccinia ankara vaccine and to see how well it works in treating pediatric patients

vaccinia
multi-peptide cmv-modified vaccinia ankara vaccine
stem cell transplantation
immunosuppressive agents
HIV Infection
  • 2 views
  • 05 Jul, 2022
  • 1 location