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Found 100 clinical trials
Optimal antiPlatelet Therapy for High Bleeding and Ischemic RISK Patients Trial

evaluated whether clopidogrel monotherapy reduce the risk of bleeding compared with clopidogrel plus ASA in the following 9 months and achieved non-inferior outcomes in preventing ischemic risk.

  • 8 views
  • 26 Jan, 2021
  • 1 location
Antiplatelet Therapy in Acute Mild-Moderate Ischemic Stroke

The risk of early recurrence or progression of acute ischemic stroke is very high, even in patients treated with aspirin. The Chance study show that clopidogrel plus aspirin treatment reduced

aspirin
transient ischemic attack
stroke
deficit
clopidogrel
  • 4 views
  • 15 Feb, 2021
  • 1 location
Study to Gather Information About the Proper Dosing and Safety of the Oral FXIa Inhibitor BAY 2433334 in Patients Following an Acute Heart Attack

(acetylsalicylic acid +/- clopidogrel) in patients following a recent heart attack (myocardial infarction) that happens when a blood vessel in the heart suddenly becomes blocked. BAY 2433334, works by blocking a

aspirin
antiplatelet therapy
angiography
clot
clopidogrel
  • 57 views
  • 01 Aug, 2021
  • 193 locations
Balloon Angioplasty for Symptomatic Intracranial Artery Stenosis

Intracranial atherosclerotic disease (ICAD) is the most common cause of ischemical cerebrovascular events. The risk of stroke recurrence or death of ICAD patients remains very high. Even with aggressive medical management including dual antiplatelet therapy and strict management of risk factors, 12.2 percent of patients with 70-99 percent stenosis of …

  • 0 views
  • 28 Jan, 2021
  • 23 locations
Second Enhanced Control of Hypertension and Thrombectomy Stroke Study (ENCHANTED2)

ENCHANTED2 is an international, multicenter, prospective, randomised, open, blinded end-point assessed (PROBE) trial, to assess different approaches to manage blood pressure (BP) in acute ischemic stroke (AIS) patients who have undergone mechanical thrombectomy (MT). There are two nested substudies evaluating different approaches to secondary prevention in this high-risk stroke population.

  • 0 views
  • 25 Jan, 2021
  • 1 location
The Clopidogrel and Aspirin After Surgery for Coronary Artery Disease

Clopidogrel is a antiplatelet agent and is effective at reducing intimal hyperplasia in animal models of thrombosis.Several large clinical trials have demonstrated that clopidogrel with

coronary disease
clopidogrel
aspirin
arterial disease
  • 9 views
  • 07 Nov, 2020
  • 1 location
Peptic Ulcer Disease in Ischemic Heart Patients Taking Aspirin and Clopidogrel With or Without Proton Pump Inhibitor

Studies showed that combined use of clopidogrel and aspirin had a 25 % reduction of risk on myocardial infarction and stroke in patients who undergone percutaneous coronary intervention

aspirin
percutaneous coronary intervention
proton pump inhibitors
lansoprazole
bleeding ulcer
  • 0 views
  • 07 Nov, 2020
  • 1 location
Platelet REACtivity According to TICagrelor Dose After Transcatheter AorticValve Implantation

during the first months after the procedure. This treatment is not yet well established. Current guidelines recommend dual antiplatelet therapy with Aspirin and Clopidogrel for 3-6 months after TAVI to

  • 0 views
  • 04 Aug, 2021
  • 1 location
A Study to Evaluate Safety and PK of Multiple Doses of LT3001 Drug Product and Drug-drug Interaction in Healthy Subjects

This Phase 1 study is planned to establish the clinical safety and pharmacokinetics profile of multiple dose of LT3001 drug product and to investigate drug interactions of LT3001 with potential concomitant medications in healthy subjects.

  • 0 views
  • 28 Mar, 2021
  • 1 location
External Counterpulsation Therapy for Severe Steno-occlusive Intracranial Stenosis

Intracranial stenosis is prevalent among Asians and constitute a common cause of cerebral ischemia. While the best medical therapy carries stroke recurrence rates in access of 10% per year, intracranial stenting was associated with unacceptable peri-procedural ischemic events. Cerebral ischemic events are strongly related to the severity of intracranial stenosis, …

ischemia
acute stroke
stenosis
cerebral infarction
stroke
  • 12 views
  • 22 Jan, 2021
  • 1 location