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Found 10 clinical trials
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AALL1131, A Phase III Randomized Trial for Newly Diagnosed High Risk B-precursor Acute Lymphoblastic Leukemia (ALL) Testing Clofarabine (IND# 73789) in the Very High Risk Stratum.

AALL1131, A Phase III Randomized Trial for Newly Diagnosed High Risk B-precursor Acute Lymphoblastic Leukemia (ALL) Testing Clofarabine (IND# 73789) in the Very High Risk Stratum.

  • 216 views
  • 08 Nov, 2020
  • 1 location
Bisantrene Combination for Resistant AML

An Open-label, Phase II, Two-stage, Study of Xantrene (Bisantrene) in combination with Fludarabine and Clofarabine as Salvage Therapy for Adult Patients with Relapsed or Refractory Acute Myeloid

carbon monoxide
ejection fraction
fludarabine
clofarabine
  • 0 views
  • 30 Sep, 2021
  • 1 location
Clofarabine Pre-conditioning Followed by Stem Cell Transplant for Non-remission AML

The Investigators would like to study the incidence of complete remission (CR) at day +30 after Clofarabine followed by haploidentical transplant. The conditioning regimen used is Fludarabine

tacrolimus
cyclophosphamide
serum bilirubin level
total body irradiation
granulocyte colony stimulating factor
  • 0 views
  • 18 Oct, 2021
  • 1 location
Trial of the Combination of Bortezomib and Clofarabine in Adults With Relapsed Solid Tumors

own to treat some blood cell cancers. Objectives To test the safety and efficacy of the drug combination of bortezomib and clofarabine.

chemotherapy regimen
neutrophil count
cancer
lymphoma
neuropathy
  • 25 views
  • 18 May, 2022
  • 1 location
Clofarabine Idarubicin Cytarabine Vincristine Sulfate and Dexamethasone in Treating Patients With Newly Diagnosed or Relapsed Mixed Phenotype Acute Leukemia

This phase II trial studies how well clofarabine, idarubicin, cytarabine, vincristine sulfate, and dexamethasone work in treating patients with mixed phenotype acute leukemia that is newly

ejection fraction
cytarabine
acute leukemia
cancer
dexamethasone
  • 22 views
  • 05 Nov, 2021
  • 1 location
Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia Lymphoblastic Lymphoma Burkitt Lymphoma/Leukemia or Double-Hit Lymphoma/Leukemia

, or double-hit lymphoma/leukemia that has come back or does not respond to treatment. Drugs used in chemotherapy, such as clofarabine, etoposide, cyclophosphamide, vincristine sulfate liposome

etoposide
vincristine
lymphocytic leukemia
combination chemotherapy
lymphoid leukemia
  • 27 views
  • 24 Jan, 2021
  • 2 locations
Post Transplant Cyclophosphamide (PTCY) as Sole Graft Versus Host Disease (GVHD) Prophylaxis for Matched Allotransplant: CYRIC (CYRIC)

Acute or chronic graft versus host disease is still the major complication of stem cells transplantation regarding morbidity and mortality. Recently, high dose cyclophosphamide utilization early after post-transplantation (day+ 3 and +4) not only for patients with HLA- haploidentical donor but also for patients with Human Leukocyte Antigen (HLA)-compatible donor, …

mycophenolate
cyclophosphamide
immunosuppressive agents
cyclosporine
cell transplantation
  • 6 views
  • 07 Feb, 2022
  • 1 location
Study of a Geriatric Assessment to Plan a Treatment Approach for Older People With Various Blood Disorders

This study will evaluate whether a geriatric assessment can lead to better treatment outcomes in older patients (age 60+) with a myeloid malignancy including acute myeloid leukemia, ,myelodysplastic syndromes, myeloproliferative neoplasms, or related blood disorders who are going to receive chemotherapy or another treatment to prepare the body for an …

transplant conditioning
leukemia
myeloid leukemia
chronic myelomonocytic leukemia
chronic myeloid leukemia
  • 0 views
  • 22 Mar, 2022
  • 7 locations
Personalized NK Cell Therapy After Chemotherapy and Cord Blood Transplant in Treating Patients With Myelodysplastic Syndrome, Leukemia, Lymphoma or Multiple Myeloma

This phase II clinical trial studies how well personalized natural killer (NK) cell therapy works after chemotherapy and umbilical cord blood transplant in treating patients with myelodysplastic syndrome, leukemia, lymphoma or multiple myeloma. This clinical trial will test cord blood (CB) selection for human leukocyte antigen (HLA)-C1/x recipients based on …

autologous hematopoietic stem cell transplant
anti-thymocyte globulin
lymphocyte immune globulin
lymphocytic leukemia
lymphoma
  • 58 views
  • 06 May, 2022
  • 1 location
Umbilical Cord Blood Transplant With Added Sugar and Chemotherapy and Radiation Therapy in Treating Patients With Leukemia or Lymphoma

This phase II trial studies how well an umbilical cord blood transplant with added sugar works with chemotherapy and radiation therapy in treating patients with leukemia or lymphoma. Giving chemotherapy and total-body irradiation before a donor umbilical cord blood transplant helps stop the growth of cells in the bone marrow, …

autologous hematopoietic stem cell transplant
anti-thymocyte globulin
bone marrow procedure
lymphocyte immune globulin
lymphocytic leukemia
  • 36 views
  • 28 Jan, 2022
  • 1 location