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Found 9 clinical trials
Beta-Lactam Containing Regimen for the Shortening of Buruli Ulcer Disease Therapy

demonstrated that beta-lactams combined with rifampicin and clarithromycin are synergistic against M. ulcerans in vitro. Amoxicillin/clavulanate is oral, suitable for treatment in adults and children, and

  • 08 Jan, 2022
  • 3 locations
Decompression of Odontogenic Cysts Using an Appliance Fabricated With a Fully Digital Workflow

The aim of this prospective case series is to present clinical results with cystostomy, decompression and final enucleation of odontogenic cysts using a decompression device fabricated with a full digital workflow and delivered on the day of cystostomy. The secondary purpose of our study is to present the volumetric changes …

  • 10 Mar, 2022
The Evaluation of the Effect of Performing Guided Lid Surgery

to evaluate the percentage of bone volume regain along with postoperative pain in cases done using the bone lid technique in comparison with those done using the conventional cyst enucleation technique.

Accepts healthy volunteers
  • 13 May, 2022
  • 1 location
Switch to Oral Antibiotics in Gram-negative Bacteremia (SOAB)

. The bloodstream isolate must be susceptible to amoxicillin, amoxicillin-clavulanate, fluoroquinolones, oral cephalosporins and/or trimethoprim-sulfamethoxazole and the subject must be able to take

  • 18 Apr, 2022
  • 7 locations
A Multicentre Randomized as a Double Blind Study Triple Placebo Comparative of the Efficacy and Safety of an Association Secnidazol-Ciprofloxacin Compared With Amoxicillin-Clavulanic Acid for the Treatment of Uncomplicated Episode of Diverticular Sigmo ditis Among Adults

The primary outcome measure is to compare efficacy of an association of Secnidazol(2g)-Ciprofloxacin(1g) (during 3 days) versus 3g of Amoxicillin-Clavulanic Acid during 10 days for the Treatment of Uncomplicated Episode of Diverticular Sigmoïditis Among Adults in clinical and biological cure. The cure rate will be evaluated at the second visit …

  • 08 Nov, 2020
  • 1 location
Prophylaxis of Surgical Wound Infection in Incisional Hernia Repair With Topical Antibiotics (PROTOP-PAR) ((PROTOP-PAR))

Surgical site infection (SSI) is the main complication of surgery. The prevention of superficial SSI by topical prophylaxis is controversial. Human studies on wound lavage with topical solutions (saline, antiseptics or antibiotics) are old and do not yield conclusive results. In experimental conditions there is evidence in favor of the …

wound infections
incisional hernia
incisional hernia repair
  • 04 Oct, 2022
  • 1 location
Peri-Implant Marginal Bone Loss And Implant Stability In Maxillary Implant Overdenture When Using Osseodensification Versus Conventional Drills: A Randomized Clinical Trial

Is to compare between the conventional drills versus osseodensification drills for implant stability and peri-implant marginal bone loss in maxillary implant overdenture.

Accepts healthy volunteers
  • 16 Oct, 2022
An Investigator Initiated, Phase IV Single-Center, Randomized, Open-Label, Prospective Study to Determine the Impact of Serial Procalcitonin on Improving Antimicrobial Stewardship and on the Efficacy, Safety, and Tolerability of Imipenem - Relebactam Plus Vancomycin or Linezolid Versus Standard of Care Antipseudomonal Beta-Lactams Plus Vancomycin or Linezolid as Empiric Therapy in Febrile Neutropenic Adults With Cancer

This phase II trial studies the effect of imipenem-relebactam in treating patients with cancer who have a fever due to low white blood cell counts (febrile neutropenia). In this study, imipenem-relebactam will be compared to the standard-of-care treatment (cefepime, meropenem, or piperacillin/tazobactam) for the treatment of febrile neutropenia. Imipenem-relebactam is …

cell transplantation
  • 25 Oct, 2022
  • 1 location
Antibiotic Dosing in Geriatric Patients at the Emergency Department (AGED)

specific Amoxicilline-Clavulanate, Piperacillin-Tazobactam and Temocillin) are attained in frail patients admitted to the geriatric department.

antibiotic therapy
  • 24 Mar, 2022
  • 1 location