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Found 8 clinical trials
Safety and Efficacy of Low Temperature Rota-flush Solution in Patients With Severe Calcified Lesion (LOTA-II) (LOTA-II)

Calcified lesions related to coronary artery are a type of atherosclerosis, accompanied by severe calcified lesions of the stenosis, which is a difficult point for PCI interventional therapy. Calcified lesions have poor response to balloon dilatation and the device can not be successfully placed, which reduce the success rate of …

single coronary artery
  • 06 May, 2022
  • 9 locations
BTE and Pulsed Waveforms for Cardioversion of Atrial Fibrillation - Escalation Strategy and Manual Pressure

> The secondary cardioversion safety outcome measures are: markers for myocardial necrosis (high sensitive troponin I, CK-MB) evaluated on blood samples taken before and 8-12 hours after cardioversion

  • 12 Aug, 2022
  • 1 location
Intracoronary of Nicorandil and Verapamil to Reduce the Occurrence of Periprocedural Myocardial Injury

Percutaneous coronary intervention (PCI) remains the major revascularization strategy for patients with obstructive coronary artery disease (CAD).However,in a substantial number of PCI cases for acute coronary syndrome (ACS) and chronic coronary syndrome (CCS),periprocedural myocardial injury or myocardial infarction (MI) occurs,both these PCI-related complications may be associated with an increased risk …

percutaneous coronary intervention
acute coronary syndrome
myocardial infarction
  • 17 Jun, 2022
  • 1 location
Safety and Efficacy of Low Temperature Contrast in UAP Patients During PCI (LOTA-I)

Percutaneous coronary intervention (PCI) has become one of the main treatments for rapid recovery of revascularization in patients with coronary heart disease (CHD). PCI has some advantages, such as easy operation, small trauma and rapid recovery. It can significantly improve myocardial ischemic symptom and reduce the incidence of cardiovascular adverse …

angina pectoris
heart disease
unstable angina
percutaneous coronary intervention
  • 06 May, 2022
  • 9 locations
Electroacupuncture for Heart Protection: Clinical Application in Patients Undergoing Cardiac Bypass Surgery (EA-CABG)

Coronary artery disease (CAD) is the leading cause of death and disability in Singapore and worldwide. Many patients with multi-vessel CAD require surgical revascularisation by coronary artery bypass graft (CABG) surgery, and are at risk of postsurgical complications such as peri-operative myocardial injury (PMI), left ventricular dysfunction, heart failure, and …

  • 17 Sep, 2022
  • 1 location
Helping Stroke Patients With ThermoSuit Cooling (SISCO)

The aim of this study is to assess the feasibility of using the Life Recovery Systems ThermoSuit Device to induce therapeutic hypothermia (32-34°C) in victims of ischemic stroke. This feasibility clinical study will enroll a total of 30 patients with acute ischemic stroke at four clinical centers. Subjects will receive …

ischemic stroke
  • 22 Jul, 2022
  • 3 locations
Prospective Cohort Study on Minimal Invasive Coronary Surgery

CABG technology is recognized as the preferred treatment, and its major adverse cardiac and cerebral event(MACCE) incidence and mortality are lower than percutaneous coronary intervention(PCI). However, the traditional CABG procedure requires sternal incision, large trauma and long recovery period after surgery. How to reduce trauma and treat multiple complex coronary …

  • 26 Jan, 2021
  • 1 location
Neurogenic Myocardial and Lung Injury in SAH Patients

Up to this day, little is known whether the extent of brain damage in patients with SAH correlates with the degree neurogenic myocardial injury and neurogenic lung injury. This is a prospective observational study designed to asses relationship between catecholamine surge and development of myocardial and lung injury in subarachnoid …

diagnostic procedures
mechanical ventilation
assisted ventilation
  • 17 Jun, 2022
  • 1 location