Found 10 clinical trials
3-year Study in Dry Eye Disease Patients With Severe Keratitis Receiving Ikervis (1mg/mL Ciclosporin)
complications in Dry Eye Disease (DED) patients with severe keratitis receiving Ikervis (1mg/mL ciclosporin) eye drops administered once daily
- 53 views
- 23 Jan, 2021
- 54 locations
A Study in Healthy Adult Participants to Assess the Effects of Ciclosporin Administration on Rilematovir
The purpose of this study is to evaluate the pharmacokinetic (PK) of a single-dose of rilematovir co-administered with a single-dose of ciclosporin compared to a single-dose administration of
- 0 views
- 31 Dec, 2021
- 1 location
NMF-CsA-Dupi Trial
systemic treatment (ciclosporin and dupilumab) in moderate-to-severe atopic dermatitis.
- 0 views
- 26 Aug, 2021
- 1 location
Prospective Multicentric Phase II Randomized Controlled Trial on Two Parallel Groups Comparing the Efficacy of Two Immunosuppressive Drugs (Methotrexate Cyclophosphamide) in Large Granular Lymphocytes Leukemia
LGL leukemia represents a rare subtype of chronic T or NK lymphoproliferative disorders. It is an indolent disease, the main hematological or autoimmune complications lead to a treatment in more than 60% of patients. Investigators set up at the University Hospital of Rennes, a database of more than 300 patients …
- 33 views
- 05 Sep, 2021
- 65 locations
Ciclosporin A Preconditioning for Renal Artery Stenosis
. Ciclosporin A can prolong mPTP closing during reperfusion and reduce renal and cardiac tissular lesions. Another mPTP blocker (Bendavia) has been associated with an improvement of renal blood flow (RBF) and
- 6 views
- 09 Jun, 2021
- 2 locations
ATG in HLA-matched Sibling HSCT as GVHD Prophylaxis
The protocols including ciclosporin A CsA+methotrexate (MTX) +mycophenolate Mofetil(MMF) have been widely used for graft-versus-host disease (GVHD) prophylaxis in allogeneic hematopoietic stem
- 0 views
- 23 Jan, 2021
- 1 location
Glucose Disorders Induced by Tacrolimus on Pre Transplantation Endstage Renal Disease Patients
contraindication to tacrolimus at the time of transplantation and ciclosporin therapy will be preferred.
- 2 views
- 22 Mar, 2021
- 3 locations
RCT Comparing Immunosuppressive Regimens in Elderly Renal Transplant Recipients
Open label, randomized, multicenter, intervention trial comparing standard immunosuppression with tacrolimus and mycophenolate mofetil with a low exposure tacrolimus regimen in combination with everolimus. The primary objective is to test the hypothesis that an age-adapted immunosuppressive regimen targeted at reduced immunosuppression with low calcineurin inhibitor (tacrolimus) exposure in combination with …
- 5 views
- 27 Jan, 2021
- 7 locations
PsoBest - The German Psoriasis Registry
. fumaric acids, methotrexate, ciclosporin A) and biological treatment (e.g. adalimumab, etanercept). While short- and middle-term efficacy of most systemic treatments has been shown in clinical studies
- 59 views
- 22 Jan, 2021
- 1 location
Evaluation of Interaction Between Immunosuppressive Drugs and Protein-bound Uremic Toxins in Renal Transplant Patients
The majority of studies conducted on uremic toxins involve patients before end stage renal failure or dialysis patients. Only a few studies have focused on transplant patients. In addition, the relationship between serum concentrations of uremic toxins and immunosuppressive drug concentrations has never been studied to date. The investigator research …
- 0 views
- 25 Jul, 2021
- 1 location