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Found 574 clinical trials
Prevention of Persistent Pain With LidocAine iNfusions in Breast Cancer Surgery (PLAN)

Phase III, international multicentre, parallel group, blinded, 1:1 randomized controlled trial to determine the effect of an intraoperative intravenous lidocaine infusion on reducing the development of persistent pain 3-months after breast cancer surgery.

lidocaine
mastectomy
cancer
anesthesia
lumpectomy
  • 10 views
  • 12 Mar, 2022
  • 4 locations
SMART Stepped Care Management for Low Back Pain in the Military Health System (SMART LBP)

This study will be sequential, randomization trial where patients with chronic low back pain are initially randomized to receive 1 of 2 treatments (physical therapy OR Move 2 Health). This will be Phase I of the study intervention. Patients who do not respond to treatment after 6 weeks will undergo …

analgesia
back pain
low back pain
pain relieving
lumbar disc herniation
  • 178 views
  • 04 Oct, 2022
  • 4 locations
Persistent PostConcussion-Like Symptoms and Post Traumatic Stress Disorder in Patients Presenting at the Emergency Room. (SOFTERIV)

IV offers the opportunity to evaluate the impact of a psychological intervention to reduce the incidence of chronic pain. By acting on the emotions experienced in the Emergency Department, a

  • 0 views
  • 07 Apr, 2022
  • 6 locations
A Depression and Opioid Pragmatic Trial in Pharmacogenetics (DCRI Coordinating Center) (ADOPT PGx)

are the Acute Pain Trial, the Chronic Pain Trial, and the Depression Trial. Participants can enroll in only one of the three trials. Acute Pain Trial: A prospective, multicenter, two arm

tramadol
chronic pain
pain relieving
depressed mood
opioid
  • 299 views
  • 04 Oct, 2022
  • 10 locations
A Randomized Clinical Trial to Evaluate Non-Pharmacologic and Pharmacologic Approaches for Reducing Pain and Opioid Use Among Patients Treated With Maintenance Hemodialysis (HOPE)

HOPE is a randomized clinical trial that will evaluate approaches to reducing pain and opioid use among patients with chronic pain who are receiving maintenance hemodialysis for end-stage renal

motivational interviewing
chronic pain
opioid
buprenorphine
opioid use
  • 31 views
  • 21 Oct, 2022
  • 15 locations
Pragmatic RCT of SBIRT-PM

Veterans seeking compensation for musculoskeletal (MSD) conditions often develop chronic pain and are at high risk for substance misuse. The Investigators propose to test the effectiveness and

analgesia
pain relieving
chronic pain
  • 13 views
  • 04 Jun, 2022
  • 8 locations
A Randomised, Double-Blind, Placebo-Controlled, Dose-Response Study of the Efficacy and Safety of MEDI7352 in Subjects With Painful Diabetic Neuropathy

This is a study investigating the effect of MEDI7352 on chronic pain in patients with painful diabetic neuropathy. The study incudes a screening period of up to 45 days and a 12-week

NSAID
painful diabetic neuropathy
chronic pain
administered intravenously
body mass index
  • 168 views
  • 11 Oct, 2022
  • 29 locations
Syndrome Fibromyalgique en France : Place de l'évaluation et de la Prise en Charge Des Troubles du Sommeil (FIBOBS)

The FIBOBS study is a multi-centered, observational, prospective study carried out within specialized chronic pain structures (CPS) in France. It will estimate the prevalence of sleep disorders

chronic pain
  • 17 views
  • 23 Oct, 2022
  • 41 locations
Spinal Manipulation and Patient Self-Management for Preventing Acute to Chronic Back Pain (PACBACK)

LBP and prevent transition to chronic back pain. The US is in the midst of an unprecedented pain management crisis. LBP is the most common chronic pain condition in adults and the leading cause

analgesia
secondary prevention
chronic pain
pain relieving
opioid
  • 651 views
  • 04 Oct, 2022
  • 2 locations
Outcomes Mandate National Integration With Cannabis as Medicine (OMNI-Can)

This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.

medical marijuana
brimonidine tartrate ophthalmic solution
disease or disorder
covid-19
Accepts healthy volunteers
  • 15192 views
  • 13 Jun, 2022
  • 16 locations