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Found 686 clinical trials
SMART Embedded Intervention for Military Postsurgical Engagement Readiness (SEMPER)

The overarching objective of this proposal is to conduct a multi-site Sequential Multiple Assignment Randomized Trial (SMART) across multiple Military Health System (MHS) sites to optimize the sequencing and integration of two intervention strategies in total knee arthoplasty (TKA) patients: a single-session mindfulness-based intervention (MBI) and an intensive 8-week MBI-Mindfulness-Oriented …

  • 0 views
  • 04 Oct, 2022
  • 1 location
ARTERIAL EMBOLIZATION OF PERSISTENT GENICULATE ARTERIES FOR CHRONIC PAIN MANAGEMENT AFTER TOTAL KNEE-REPLACEMENT ARTHROPLASTY(KNEE EMBOLISATION)

Recent works in interventional radiology have shown interesting results in the treatment of musculoskeletal inflammatory sites by arterial embolization. Supra-selective arterial embolization has been successfully developed by Dr. Okuno (Japan) to manage moderate to severe knee osteoarthritis. Also, inflammation of the surgical site mediated via geniculate arteries is a major …

  • 3 views
  • 21 Aug, 2021
  • 1 location
Effects of Self-mobilization Techniques on Pain, Range of Motion and Function in Patients With Chronic Pain

A Randomized clinical trial will be conducted at Actilife physiotherapy Rehabilitation center, Horizon Hospital Lahore through a convenient sampling technique on patients who will be allocated using simple random sampling through sealed opaque enveloped into Group A and Group B. Group A will be treated with the self-mobilization technique of …

  • 0 views
  • 21 Oct, 2022
Study of Efficacy and Safety of SAF312 Eye Drops in Subjects With Post-operative Corneal Induced Chronic Pain (CICP)

The study is designed to demonstrate the safety and efficacy of two dose concentrations of SAF312 eye drops (dose 1 and dose 2) in subjects with CICP persisting at least for 4 months after refractive or cataract surgery and chronicity confirmed during the observational period. The study will also determine …

  • 28 views
  • 04 Oct, 2022
  • 31 locations
A 6-month, Double-blinded, Sham-controlled Clinical Trial Assessing the Clinical Usefulness of Radiofrequency Ablation for Chronic Knee Pain After Total Knee Arthroplasty (RACKTKA)

The purpose of this study is to assess how clinically useful and safe genicular nerve radiofrequency ablation is in people with chronic pain after total knee arthroplasty performed for

  • 0 views
  • 14 Oct, 2022
  • 1 location
Acute & Chronic Post-mastectomy Pain: Can PECS Block Alter the Geography?

Post mastectomy pain management is of crucial importance for patients' rehabilitation and quality of life. PECS block is used for acute and chronic post mastectomy pain management. Surgical infiltration is also used in this field. Patients in our study are divided in two groups receiving PECS block or surgical infiltrationbefore …

  • 0 views
  • 24 Jan, 2021
  • 1 location
Impact of Kinesiophobia on Descending Corticospinal and Bulbospinal Projections (EchoKinésio)

Fear of movement (kinesiophobia) is a phenomenon commonly observed in people suffering from chronic pain. The aims of this project are to better understand the neurophysiological basis of this

Accepts healthy volunteers
  • 0 views
  • 23 Mar, 2022
  • 1 location
Pain and Quality of Life After Inguinal Hernia Repair. Randomized Study Comparing Laparoscopic TAPP Repair With Open Lichtenstein Repair (QoL-TAPP Study) (QoL-TAPP)

. Chronic pain, restriction of activities and esthetical outcome will be evaluated preoperatively and postoperatively, at 1, 4 and 12 months, using the European Registry for Abdominal Wall Hernias Quality

chronic pain
herniorrhaphy
repair of inguinal hernia
  • 9 views
  • 27 Oct, 2022
  • 1 location
Identifying Correlates of Brain Microglial Activation in Neuropsychiatric Syndromes: A Dimensional Approach

, chronic pain syndrome, dementia, traumatic brain injury, or substance abuse. The research will also explore whether there is more inflammation in patients with more neuropsychiatric symptoms. Inflammation

Accepts healthy volunteers
  • 206 views
  • 15 Feb, 2022
  • 1 location
Testing the Effects of Transcutaneous Electrical Nerve Stimulation (TENS) on Chemotherapy-Induced Peripheral Neuropathy (CIPN)

diseased. The TENS device emits high frequency electrical stimulation through the skin and may provide relief from chronic pain.

peripheral neuropathy
spinal cord
alkaloids
vinca alkaloid
paresthesia
  • 263 views
  • 05 Mar, 2022
  • 15 locations