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Found 85 clinical trials
Multidimensional Individualized Nutritional Therapy for Individuals With Severe COPD (MINDNUT)

Individuals with severe chronic pulmonary disease often life isolated with a high burden of symptoms. Nutritional risk and low quality of life are common, and both associated with increased

  • 21 Mar, 2022
The Effect of Interval Exercise on Functional Outcomes in Veterans With COPD and OSA

) evaluates functional status in chronic pulmonary disease globally in 5 domains. The investigators propose to study validated outcomes in 3 of these domains: 1) participation in life situations; 2) physical

  • 10 May, 2022
  • 1 location
Doxapram Therapy in Preterm Infants (DOXA Trial)

disadvantage of being a major risk of chronic lung disease and impaired neurodevelopmental outcome. Restrictive invasive ventilation is therefore advocated nowadays in preterm infants. Doxapram is a

pulmonary disease
mechanical ventilation
continuous positive airway pressure
assisted ventilation
  • 25 Jan, 2021
  • 18 locations
High VS Low Flow Nasal O2 for Acute Hypercapnic Respiratory Failure

Chronic lung conditions such as smoking related lung damage lead to breathing fail. This results in accumulation of gases such as carbon-di-oxide in the body especially during periods of illness

  • 05 May, 2022
  • 2 locations
High Flow Nasal Cannula Versus Non-Invasive Ventilation in Exacerbations of Chronic Obstructive Pulmonary Disease

. Recent studies have shown that the technique is very efficient to treat patients presenting with acute respiratory failure who don't have any underlying chronic pulmonary disease. Whether the technique

acute respiratory failure
obstructive lung disease
tobacco smoke
pulmonary disease
  • 06 Jul, 2021
  • 1 location
L-citrulline and Pulmonary Hypertension Associated With Bronchopulmonary Dysplasia

Bronchopulmonary dysplasia (BPD) is a chronic lung disease that affects up to 35% of very low birth weight infants (VLBW < 1500 g). Based on the current numbers of VLBW infants born annually

very low birth weight
assisted ventilation
chronic lung disease
  • 22 Mar, 2022
  • 1 location
Intratracheal Umbilical Cord-derived Mesenchymal Stem Cell for the Treatment of Bronchopulmonary Dysplasia (BPD) (IUMTB)

Umbilical Cord-derived Mesenchymal stem cell has been proven effective in the experimental bronchopulmonary dysplasia (BPD).A multi-center study was designed to evaluate the safety and efficacy of the cellular therapy in extremely preterm infants at high risk for BPD.

cellular therapy
  • 27 Feb, 2022
  • 3 locations
Human Mesenchymal Stem Cells For Bronchopulmonary Dysplasia

This study is an open-label, single-center, dose escalation study to evaluate of safety and efficacy of human umbilical cord -derived mesenchymal stem cells (hUC-MSCs) in premature infants for moderate and severe Bronchopulmonary DysplasiaBPD.

severe bronchopulmonary dysplasia
premature birth
  • 04 Mar, 2022
  • 1 location
Hyperpolarized 129Xe MRI for Imaging Pulmonary Function

The purpose of this study is to develop and evaluate the usefulness of MRI using 129Xe gas for regional assessment of pulmonary function. Specifically, three forms of 129Xe MRI contrast will be the investigators focus - 1) imaging of the 129Xe ventilation distribution, 2) imaging the alveolar microstructure via the …

pulmonary disease
Accepts healthy volunteers
lung disease
  • 21 Oct, 2021
  • 1 location
Effect of a Parenteral Emulsion With Omega3 on PPHN (PPHN-N3)

The purpose of this study is to evaluate the effect of a parenteral emulsion containing n-3 long-chain polyunsaturated fatty acids (LC-PUFA) in fish oil on clinical outcomes, markers of inflammation and oxidative stress, and pain in neonates with persistent pulmonary hypertension of the newborn (PPHN) compared with those who receive …

  • 25 Mar, 2022
  • 1 location