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Found 85 clinical trials
Extended-Duration Low-Intensity Apixaban to Prevent Recurrence in High-Risk Patients With Provoked Venous Thromboembolism

Design: U.S.-based, single-center, randomized placebo-controlled trial. Brief Treatment Description: Low-intensity apixaban (2.5mg twice daily) for extended-duration secondary prevention of VTE after initial treatment for provoked VTE. Purpose: To establish the safety and efficacy of low-intensity apixaban versus placebo for extended prevention of recurrence after provoked VTE in patients with at …

anticoagulant therapy
thromboembolism
apixaban 2.5 mg
embolism
stroke
  • 0 views
  • 11 Jul, 2021
  • 1 location
Project to Improve Communication About Serious Illness--Hospital Study: Comparative Effectiveness Trial (Trial 2) (PICSI-H)

The objective of this protocol is to test the effectiveness of a Jumpstart intervention on patient-centered outcomes for patients with chronic illness by ensuring that they receive care that is concordant with their goals over time, and across settings and providers. This study is particularly interested in understanding the effect …

peripheral vascular disease
diabetes
cancer
psychological symptoms
liver disease
  • 0 views
  • 21 Mar, 2022
  • 2 locations
Intra-tracheal Instillation of Budesonide to Prevent Chronic Lung Disease (STOPCLD)

Preterm infants are randomized to received either Intra-tracheal instillation of budesonide using surfactant as vehicle or a placebo. Intra-tracheal instillation of budesonide using surfactant as vehicle would facilitate its delivery to the periphery of the lung and would inhibit lung inflammation and mitigate acute lung injury.

  • 0 views
  • 14 May, 2022
  • 1 location
Trial of Bone-marrow Derived Mesenchymal Stromal Cells (MSC) for New Onset Chronic Lung Allograft Dysfunction (ASSIST-CLAD)

This study is designed for lung transplant patients who have developed chronic lung allograft dysfunction (CLAD). Consented patients will receive 4 intravenous doses of allogeneic, bone-marrow

  • 64 views
  • 25 Feb, 2022
  • 3 locations
Chronic Lung Disease and COVID-19: Understanding Severity Recovery and Rehabilitation Needs

This is study is comprised of three approaches. First, the investigators will conduct a retrospective cohort study to provide rapid initial guidance for rehabilitation programs to anticipate care needs of COVID-19 survivors. The investigators will also conduct a mixed-methods study and follow COVID-19 patients with repeated surveys to determine patient-reported …

  • 0 views
  • 11 Dec, 2021
  • 1 location
4DX Functional Lung Imaging in the Diagnosis of Chronic Lung Allograft Dysfunction After Lung Transplantation

This is a pilot study to determine the utility of Novel Functional Lung Imaging and Ventilation (4DxV) Analysis software in measurement of lung ventilation abnormalities and diagnosis of chronic

  • 0 views
  • 12 May, 2022
  • 1 location
BPD Saturation TARgeting (BPD STAR)

Bronchopulmonary dysplasia (BPD), or chronic lung disease of prematurity, affects nearly half of extremely preterm infants.This study evaluates the use of supplemental oxygen to manage infants

severe bronchopulmonary dysplasia
pulmonary disease
premature birth
chronic lung disease
prematurity
  • 0 views
  • 14 Mar, 2022
  • 3 locations
Continuous Versus Intermittent Bolus Feeding in Very Preterm Infants - Effect on Respiratory Morbidity (CONFER)

Chronic Lung Disease (CLD) of Prematurity is a common yet challenging co-morbidity affecting extremely premature newborns. Multifactorial influences leading to this co-morbidity is known and

premature birth
very low birth weight
respiratory morbidity
prematurity
pulmonary disease
  • 0 views
  • 24 Feb, 2022
  • 2 locations
SMOFlipid and Incidence of BPD in Preterm Infants

Despite many advances in neonatal care in the recent years, bronchopulmonary dysplasia (BPD) continues to be the major cause of chronic lung morbidity in infants. The pathogenesis of BPD is

  • 0 views
  • 26 Dec, 2021
  • 1 location
Cytokine Adsorption in Lung Transplantation

contributes to the development of chronic lung allograft dysfunction (CLAD) which is the leading cause of late mortality (2). PGD develops within the first 72 hours after LTx. The development of CLAD

  • 0 views
  • 24 Mar, 2022
  • 1 location