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Found 606 clinical trials
Effect of Different Hemodialysis Modality on Adiponectin Vascular Function and Clinical Prognosis

Adiponectin, an adipose tissue derived protein, with anti-inflammatory properties that is secreted from adipose tissue, is associated with insulin resistance. It has been shown to be a predictor of cardiovascular events in both the general population and patients undergoing hemodialysis. Adiponectin levels were inversely related to body mass index values, …

kidney replacement
maintenance haemodialysis
body mass index
  • 07 Nov, 2020
  • 1 location
NAC in Preventing CIN in CRF Patients Who Need Enhanced CT Scan in ED

The purpose of this study is to evaluate the effect of NAC or sodium bicarbonate in preventing the aggravation of renal function in chronic renal failure when enhanced computed tomography

renal failure
renal function study
  • 07 Nov, 2020
  • 2 locations
High Flux Hemodialysis Thrice Versus Once

To investigate the influence of different dialysis frequencies on the outcome of end-stage renal disease patients undergoing chronic hemodialysis therapy.

chronic haemodialysis
  • 07 Nov, 2020
To Evaluate the Patient Tolerance Pharmacodynamics and Pharmacokinetics of Lanthanum Polystyrene Sulfonate Powder

The aim of the study is: to evaluate the tolerance of lanthanum polystyrene sulfonate powder in patients with chronic kidney disease and hyperphosphatemia with multi-dose and multi-dose

lanthanum carbonate
lanthanum carbonate 500 mg
chronic kidney disease
renal disease
  • 26 Jan, 2021
  • 1 location
Evaluate the Efficacy and Safety of Multiple Roxadustat Dosing Regimens for the Treatment of Anemia in Dialysis Subjects With Chronic Kidney Disease

This is a randomized, open-label, multi-center study in dialysis CKD subjects to evaluate the efficacy and relative safety of different dosing regimens of roxadustat over a 36-week treatment

  • 26 Apr, 2021
  • 20 locations
EVOO Coratina Intervention on Lipids in Non-diabetic Hypertensive Patients Undergoing Hemodialysis (EVOOC-3H)

Twenty-four non-diabetic hypertensive and hyperlipidemic patients undergoing periodic chronic hemodialysis will be enrolled for receiving extravirgin olive oil (EVOO) Coratina (12 patients) or refined olive oil (12 patients). Aim of the study is to evaluate the effect of EVOO-C on serum lipid levels. Randomization will be done centrally with appropriate …

  • 26 Jan, 2021
  • 1 location
The Effect of High-flux Hemodialysis and On-line Hemodiafiltration on Endothelial Function.

The main aim of this project is to evaluate, in patients with chronic kidney disease (CKD5D), the role of adhesion molecules in leukocyte adhesion and transendothelial migration involved in

  • 23 Jan, 2021
  • 1 location
Modulation of Tissue Sodium in Hemodialysis Patients

Salt (NaCl) intake is implicated in causing hypertension and cardiovascular disease, the commonest cause of death worldwide. The investigators recently established that Na+ is stored in tissues, bound to glycosaminoglycans (GAGs) in skin and muscle. The resulting local hypertonicity leads to immune cell-driven induction of local tissue electrolyte clearance via …

  • 27 Jan, 2021
  • 1 location
Pilot Study of Loop Diuretics Among Individuals Receiving Hemodialysis

Individuals with kidney failure receiving maintenance hemodialysis (HD) have high mortality rates, driven largely by cardiovascular causes. Volume-related factors are critical, modifiable contributors to cardiovascular complications. Reversing volume overload has been shown to improve blood pressure and cardiac remodeling. Use of loop diuretics may represent a pragmatic, low-cost, and low-burden …

  • 26 Jan, 2021
  • 5 locations
Potential Benefits of Expanded Hemodialysis in Prevention of Sarcopenia

sarcopenia in patients with chronic kidney disease requiring hemodialysis.

  • 25 Jan, 2021