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Found 310 clinical trials
Virtual Agents-based Digital Interventions to Improve Health

KANOPEE is a free smartphone application providing screening, follow-up tools and autonomous digital interventions to lower psycho-social stress and its repercussions on sleep and behaviors in the general population. Additionally, KANOPEE permits an adaptation of the intervention to the subject (i.e., an adapted waiting period, frequency, and content), enabling to …

behavior therapy
Accepts healthy volunteers
  • 0 views
  • 19 Oct, 2021
  • 1 location
Outcomes Mandate National Integration With Cannabis as Medicine (OMNI-Can)

This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.

medical marijuana
disease or disorder
brimonidine tartrate ophthalmic solution
covid-19
Accepts healthy volunteers
  • 15164 views
  • 13 Jun, 2022
  • 16 locations
A Short-term Exploratory Study to Evaluate Safety, Tolerability and Pharmacokinetics of Seltorexant as Adjunctive Therapy to Antidepressants in Adolescents With Major Depressive Disorder Who Have an Inadequate Response to SSRI Monotherapy and Psychotherapy

The purpose of this study is to assess the safety and tolerability of Seltorexant as adjunctive therapy to an antidepressant in adolescents with major depressive disorder (MDD) in the short-term compared with placebo.

  • 1 views
  • 23 Oct, 2022
  • 14 locations
Efficacy of COMET on Prolific Participants (COMET-Prol)

In this study, the investigators will test the effectiveness of a digital, single-session mental health intervention. There will be two conditions: the COMET intervention and the control group. The program, COMET (Common Elements Toolbox), will include a variety of modules which will focus on cognitive restructuring, gratitude, behavioral activation, and …

behavior therapy
Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Implementing and Sustaining a Sleep Treatment to Improve Community Mental Health Outcomes

The sleep disturbance commonly experienced by individuals with a severe mental illness (SMI) reduces these individuals' capacity to function and contributes to key symptoms. This study will test the effects of a sleep treatment that has been adapted using theory, data and stakeholder inputs to improve the fit for SMI …

sleep disturbances
mental illness
sleep problem
  • 1104 views
  • 04 Oct, 2022
  • 8 locations
Collection of Granulocytes by Apheresis of Healthy Donors Stimulated With Filgrastim (G-CSF) and Dexamethasone

Background White blood cells called granulocytes help the body fight infection. People who have had chemotherapy or bone marrow transplants may have very low numbers of these cells. Transfusions of these cells can help improve the body's ability to fight infection. However, most of the cells are located in the …

Accepts healthy volunteers
  • 41 views
  • 28 Oct, 2022
  • 1 location
Optimized Recovery After Trauma in Geriatric Patient

Currently, there is evidence that structured care within the healthcare system increases the conditions for good care and better recovery. We want to investigate whether a new care concept (gero-ERAT) that combines two variants of structured care can improve the recovery of elderly patients affected by a physical trauma. Our …

physical trauma
  • 1 views
  • 24 Feb, 2022
  • 1 location
Interest of Auriculotherapy in the Management of Chronic Insomnia (AURICULO-DODO)

The aim of the study is to show that auriculotherapy is effective in the treatment of chronic insomnia.

chronic insomnia
  • 4 views
  • 25 Mar, 2022
  • 2 locations
Chronic Insomnia and CSF Markers of Dementia - Effects of Treatment

dementia biomarkers found in cerebrospinal fluid (CSF). Fifteen adults age 30-50 with chronic insomnia will undergo overnight polysomnography and CSF sampling in the morning. This will be followed by 8

behavior therapy
dementia
chronic insomnia
polysomnography
cognitive therapy
  • 0 views
  • 25 Mar, 2022
  • 1 location
DexmedetOmidine Complement Treats Chronic insOmnia and Improves Circadian Rhythm (DOCTOR) (DOCTOR)

controlled trial was designed to investigate whether dexmedetomidine can improve/treat chronic insomnia patients. Its effects on sleep quality and improvement, EEG and circadian rhythm, brain connectivity

body mass index
chronic insomnia
  • 5 views
  • 13 Apr, 2022
  • 1 location