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Found 214 clinical trials
Digital Rehabilitation Environment Augmenting Medical System (DREAMS)

D.R.E.A.M.S. will assess an immersive digital reality-augmenting system in reducing the occurrence of cognitive, behavioral, and emotional consequences of critical illness and environmental exposures that are risk factors for the development of delirium.

critical illness
  • 24 Aug, 2023
  • 1 location
Evaluation of the Sleep-relieving Effect of Banana Peel Extract

Banana peel has the potential to improve sleep quality. The purpose of this research is to test the effect of banana peel on improving sleep quality.

Accepts healthy volunteers
  • 06 Apr, 2023
  • 1 location
REPOSE Study: Reducing Delirium by Enhancing Postoperative Sleep With Suvorexant (REPOSE)

This research study will evaluate the effectiveness of postoperative administration of a drug called suvorexant, to improve postoperative sleep and decrease the severity of delirium (serious confusion) in adults 65 years and older undergoing non-cardiac surgery.

Accepts healthy volunteers
  • 30 Jul, 2023
  • 1 location
TICOP Mobile App and E-platform: Providing Information and Support for Parents Caring for Their Child Cancer Survivor (TICOP)

This study aims to develop a mobile App (named "TICOP") for parents of a childhood cancer survivor and an E-Platform for health professionals which work in pediatric oncology area. The core objective is to evaluate the effects of these two digital tools (mobile app and platform) in the detection and …

Accepts healthy volunteers
  • 07 Feb, 2022
Developing an Integrative, Recovery-Based, Post-Acute COVID-19 Syndrome (PACS) Psychotherapeutic Intervention

Post-Acute COVID-19 Syndrome (PACS) is a prevalent phenomenon that affects thousands of Veterans in VA care. VA patients suffering from PACS not only experience lingering physical symptoms following COVID-19 infection, but have increased mental health problems including sleep disorders, anxiety disorders, trauma and stress-related disorders as well as increased use …

  • 23 Oct, 2022
  • 1 location
Comparison of Antidepressant Augmentation With Amantadine vs Pramipexole vs Quetiapine in Treatment Resistant Depression (APQ-TRD)

The present study has been designed to compare the efficacy and safety of augmentation of SSRIs with Amantadine vs Pramipexole vs the recommended Quetiapine augmentation in Treatment-Resistant Depression (TRD) and correlate the changes in depression scores with changes in the serum levels of Brain-derived neurotrophic factor (BDNF) and Nerve growth …

  • 29 Aug, 2023
  • 1 location
Muscle Strength Exercise and Sleep Apnea

Background Obstructive sleep apnea is one of our common diseases and up to 80% of patients are estimated to be undiagnosed. Its main risk factors are overweight, age, male gender, menopause, small jaw, sedative medications / drugs and alcohol. The most important treatment for sleep apnea is continuous positive airway …

obstructive sleep apnea
continuous positive airway pressure
  • 23 Apr, 2022
Sterile Amniotic Fluid Filtrate Epidural Injection.

There is a large population of patients with lumbosacral radicular pain due to spinal stenosis who do not respond to physical therapy or oral medication management, yet wish to avoid spinal surgery or are simply not candidates due to medical co-morbidity. Given the natural history of lumbar spinal stenosis, these …

  • 06 Jan, 2022
  • 1 location
Evaluation of a New Bladder Health Mobile Application in Pregnancy (BHmApp)

Millions of women experience involuntary loss of urine called urinary incontinence (UI). UI can be slightly bothersome or totally debilitating. Women experience UI twice as often as men. Urinary incontinence can also be a persistent condition caused by underlying physical problems or changes, including pregnancy and childbirth. UI symptom severity …

Accepts healthy volunteers
pelvic floor muscle training
  • 19 Aug, 2023
  • 1 location
CBT-I or Zolpidem/Trazodone for Insomnia (COZI)

-I) for the treatment of chronic insomnia in men and women aged 18-80 living in rural areas with 1 year of follow-up. A total of 1200 participants will be enrolled and randomized in the United States

behavior therapy
cognitive behavioral therapy for insomnia
chronic insomnia
  • 05 Jul, 2022
  • 8 locations