Found 28 clinical trials
A Study to Evaluate Efficacy and Safety of Macitentan 75 mg in Inoperable or Persistent/Recurrent Chronic Thromboembolic Pulmonary Hypertension (MACiTEPH)
The purpose of the study is to evaluate the effect of macitentan 75 mg versus placebo on exercise capacity at Week 28 in participants with chronic thromboembolic pulmonary hypertension (CTEPH
- 93 views
- 19 Sep, 2023
- 148 locations
Pulmonary Embolism International THrOmbolysis Study-3 (PEITHO-3)
In this study, we will assess the efficacy and safety of a reduced dose of thrombolytic therapy given in addition to low-molecular-weight heparin in patients with intermediate-high-risk acute pulmonary embolism. Half of participants will receive thrombolytic treatment, while the other half will receive a placebo.
- 0 views
- 10 May, 2022
- 28 locations
Implementation of a Structured Post-pulmonary Embolism Follow-up Model
Venous thromboembolism (VTE), clinically presenting as deep vein thrombosis or pulmonary embolism (PE) is the third most common cardiovascular disease and is associated with substantial short- and long-term morbidity and mortality and high costs of care. In addition negative physical and mental complications following VTE are common. However in terms …
- 0 views
- 21 Sep, 2023
- 1 location
Latent Pulmonary Hypertension (PH) in Chronic Thromboembolic Pulmonary Hypertension (CTEPH )After Endarterectomy and Influence of Exercise and Respiratory Therapy
Severe CTEPH leads to an impaired physical capacity and a restricted quality of life and poor prognosis. Pulmonary endarterectomy represents the best choice as therapy, when the thrombi
- 3 views
- 04 Oct, 2022
- 1 location
Balloon Pulmonary Angioplasty in Non-operable CTEPH Patients
Balloon pulmonary angioplasty (BPA) emerged as a potential therapeutic option for non-operable patients with chronic thromboembolic pulmonary hypertension (CTEPH). The aim of this study
- 1 views
- 29 Aug, 2021
- 1 location
Initial Dual Oral Combination Therapy Versus Standard-of-care Initial Oral Monotherapy Prior to Balloon Pulmonary Angioplasty in Patients With Inoperable Chronic Thromboembolic Pulmonary Hypertension
Chronic thromboembolic pulmonary hypertension (CTEPH) is characterised by an obstruction of proximal or more distal pulmonary arteries by residual organized thrombi, combined with a variable
- 0 views
- 06 Dec, 2021
- 1 location
Hemodynamic Effects of BPA at Rest and During Exercise in CTEPH (EXPERT-BPA)
Chronic thromboembolic pulmonary hypertension (CTEPH) is characterized by obstruction of the pulmonary vasculature by residual organized thrombi, leading to increased pulmonary vascular
- 4 views
- 04 Oct, 2022
- 2 locations
Effects of Riociguat on RIght VEntricular Size and Function in PAH and CTEPH (RIVERII)
This is an open-label, single-armed, prospective single-centre clinical study to evaluate the effect of riociguat on right heart size and function in patients with manifest PAH and CTEPH.
- 0 views
- 29 Apr, 2022
- 1 location
Dapagliflozin in Pulmonary Arterial Hypertension (DAPAH)
The purpose of this study is to investigate the effects of dapagliflozin on exercise capacity and hemodynamics in patients with pulmonary arterial hypertension
- 0 views
- 23 Aug, 2023
- 1 location
HA Residents With PVD, 6MWD Assessed at HA (2840m) vs LA (Sea Level)
thromboembolic pulmonary hypertension (PH) who permanently live >2500m on 6-minute walk distance (6MWD)
- 0 views
- 27 Aug, 2023
- 1 location