Found 110 clinical trials
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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For all genders
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Currently Recruiting
Phase III, Double Blind, Placebo-Controlled, Multicenter Study of the Efficacy and Safety of Etrolizumab During Induction and Maintenance in Patients With Moderate to Severe Active Ulcerative Colitis Who Are Refractory to or Intolerant of TNF Inhibitors
Phase III, Double Blind, Placebo-Controlled, Multicenter Study of the Efficacy and Safety of Etrolizumab During Induction and Maintenance in Patients With Moderate to Severe Active Ulcerative Colitis Who Are Refractory to or Intolerant of TNF Inhibitors
- 182 views
- 23 Nov, 2020
- 1 location
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Multi-country trial
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Phase 2 trial
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
A Study of JNJ-73763989 JNJ-56136379 Nucleos(t)Ide Analogs and Pegylated Interferon Alpha-2a in Virologically Suppressed Participants With Chronic Hepatitis B Virus Infection
The purpose of this study is to evaluate the efficacy in terms of hepatitis B surface antigen (HBsAg) levels of the study intervention (that is, JNJ-73763989 + JNJ-56136379 + nucleos[t]ide analog [NA] and pegylated interferon alpha-2a [PegIFN-alpha2a].
- 0 views
- 24 Feb, 2021
- 11 locations
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Phase 4 trial
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Accepting adults
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An interventional trial
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For all genders
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Currently Recruiting
The Clinical Cure Project of Chronic Hepatitis B in China
Chronic hepatitis B is a global public health problem, with nearly 700,000 deaths each year because of hepatitis B-related diseases. Recent studies have found that some patients who have used
- 6 views
- 24 Jan, 2021
- 1 location
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Multi-country trial
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Phase 2 trial
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
A Study of JNJ 73763989+JNJ 56136379+Nucleos(t)Ide Analog (NA) Regimen Compared to NA Alone in e Antigen Negative Virologically Suppressed Participants With Chronic Hepatitis B Virus Infection
The purpose of this study is to evaluate the efficacy of 48-week study intervention with JNJ-73763989+JNJ-56136379+nucleos(t)ide analog (NA) regimen compared to NA alone assessed by HBsAg levels. This study is part of HepB Wings Platform Trial (PLATFORMPAHPB2001).
- 6 views
- 01 Mar, 2020
- 32 locations
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Phase 3 trial
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Study of the Efficacy and Safety of HS-10234 in Patients With Chronic Hepatitis B Virus Infection
hepatitis B virus (HBV) infection.
- 0 views
- 22 Jan, 2021
- 1 location
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Phase 4 trial
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Influence of Antiviral Treatment to the Long-Term Prognosis of Patients With Chronic HBV Infection
Influence of antiviral treatment to the long term prognosis of patients with chronic HBV infection. The aim of antiviral treatment for HBV is to reduce the long term severe complications. In this study, the investigators divided patients with chronic HBV infection into two groups, which start early antiviral treatment and …
- 11 views
- 07 Nov, 2020
- 2 locations
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Multi-country trial
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Phase 1 trial
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Study of Safety and Tolerability of DCR HBVS
DCR-HBVS will be evaluated for safety and efficacy in healthy volunteers and chronic hepatitis B patients.
- 150 views
- 25 Jan, 2021
- 9 locations
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Multi-country trial
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Phase 2 trial
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
A Study of JNJ-73763989 + JNJ-56136379 + Nucleos(t)Ide Analog (NA) Regimen With or Without Pegylated Interferon Alpha-2a (PegIFN- 2a) in Treatment-Naive Participants With Hepatitis B e Antigen (HBeAg) Positive Chronic Hepatitis B Virus (HBV) Infection and Normal Alanine Aminotransferase (ALT)
The purpose of this study is to evaluate the efficacy of a treatment regimen of JNJ-73763989 + JNJ-56136379 + nucleos(t)ide analog (NA) with or without pegylated interferon alpha-2a (PegIFN-2a).
- 0 views
- 06 Mar, 2021
- 57 locations
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Multi-country trial
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Phase 2 trial
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
A Study of JNJ-73763989 + Nucleos(t)Ide Analog in Participants Co-Infected With Hepatitis B and Hepatitis D Virus
The purpose of the study is to evaluate on-treatment efficacy against hepatitis D virus (HDV) of JNJ-73763989 + nucleos(t)ide analog (NA) regimen compared to NA alone.
- 0 views
- 25 Feb, 2021
- 66 locations
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Multi-country trial
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Phase 1 trial
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
A Phase 1 Double-Blinded Study for Safety Tolerability Pharmacokinetics and Antiviral Activity of ATI-2173 in Healthy Subjects and Subjects With Chronic Hepatitis B Virus Infection
body metabolizes and eliminates the investigational drug. Volunteers with a diagnosis of chronic hepatitis B virus infection will be administered multiple oral doses of ATI-2173 and assessed for safety
- 70 views
- 25 Jan, 2021
- 4 locations