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Found 249 clinical trials
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Phase III, Double Blind, Placebo-Controlled, Multicenter Study of the Efficacy and Safety of Etrolizumab During Induction and Maintenance in Patients With Moderate to Severe Active Ulcerative Colitis Who Are Refractory to or Intolerant of TNF Inhibitors

Phase III, Double Blind, Placebo-Controlled, Multicenter Study of the Efficacy and Safety of Etrolizumab During Induction and Maintenance in Patients With Moderate to Severe Active Ulcerative Colitis Who Are Refractory to or Intolerant of TNF Inhibitors

  • 182 views
  • 23 Nov, 2020
  • 1 location
featured
Eltrombopag Added to Standard Immunosuppression in Treatment-Naive Severe Aplastic Anemia

Background: Severe aplastic anemia is a rare and serious blood disorder. It happens when the immune system starts to attack the bone marrow cells. This causes the bone marrow to stop making red blood cells, platelets, and white blood cells. Standard treatment for this disease is horse-ATG and cyclosporine, which …

aplastic anemia
anemia
myelodysplastic syndrome (mds)
myelodysplastic syndromes
anemia studies
  • 123 views
  • 22 Dec, 2020
  • 1 location
The Clinical Cure Project of Chronic Hepatitis B in China

Chronic hepatitis B is a global public health problem, with nearly 700,000 deaths each year because of hepatitis B-related diseases. Recent studies have found that some patients who have used

hepatitis b surface
fibrosis
interferon
chronic hepatitis
hepatitis b antigen
  • 6 views
  • 05 Aug, 2019
  • 1 location
The Incidence of Postpartum Hepatitis in Pregnant Women With Chronic Hepatitis B Virus Infection

The majority of childbearing age women with hepatitis B virus infection were still in the immune tolerance period. Our recent research had shown that most puerperae after delivery had elevated ALT level. However, there is no withdrawal time recommendations after childbirth at present.Through the study of hepatitis occurrence after delivery …

tenofovir
fumarate
chronic hepatitis
antiviral treatment
hepatitis b e antigen
  • 5 views
  • 08 Nov, 2020
  • 1 location
Influence of Antiviral Treatment to the Long-Term Prognosis of Patients With Chronic HBV Infection

Influence of antiviral treatment to the long term prognosis of patients with chronic HBV infection. The aim of antiviral treatment for HBV is to reduce the long term severe complications. In this study, the investigators divided patients with chronic HBV infection into two groups, which start early antiviral treatment and …

lamivudine
hepatitis b e antigen
telbivudine
antiviral treatment
hepatitis b antigen
  • 11 views
  • 07 Nov, 2020
  • 2 locations
Study of Safety and Tolerability of DCR HBVS

DCR-HBVS will be evaluated for safety and efficacy in healthy volunteers and chronic hepatitis B patients.

chronic hepatitis
liver disease
  • 150 views
  • 07 Sep, 2020
  • 9 locations
A Study of JNJ 73763989+JNJ 56136379+Nucleos(t)Ide Analog (NA) Regimen Compared to NA Alone in e Antigen Negative Virologically Suppressed Participants With Chronic Hepatitis B Virus Infection

The purpose of this study is to evaluate the efficacy of 48-week study intervention with JNJ-73763989+JNJ-56136379+nucleos(t)ide analog (NA) regimen compared to NA alone assessed by HBsAg levels. This study is part of HepB Wings Platform Trial (PLATFORMPAHPB2001).

  • 6 views
  • 01 Mar, 2020
  • 32 locations
A Study of JNJ-73763989 + JNJ-56136379 + Nucleos(t)Ide Analog (NA) Regimen With or Without Pegylated Interferon Alpha-2a (PegIFN- 2a) in Treatment-Naive Participants With Hepatitis B e Antigen (HBeAg) Positive Chronic Hepatitis B Virus (HBV) Infection and Normal Alanine Aminotransferase (ALT)

The purpose of this study is to evaluate the efficacy of a treatment regimen of JNJ-73763989 + JNJ-56136379 + nucleos(t)ide analog (NA) with or without pegylated interferon alpha-2a (PegIFN-2a).

  • 0 views
  • 01 Jan, 2021
  • 50 locations
Treatment of Liver Cirrhosis Due to Hepatitis B Virus With Fuzheng Huayu and Entecavir

partially stop or reverse liver fibrosis in patients with chronic Hepatitis and liver cirrhosis due to HBV, and the anti-fibrotic strategy focusing on the regulation of hepatic extracellular matrix is still

  • 22 views
  • 08 Nov, 2020
  • 2 locations
A RCT of TNF and ENT in the Treatment of Long-term Prognosis With Hepatitis B-related HCC After Curative Resection

This study evaluates the addition of Tenofovir and Entecavir in the treatment of Hepatitis B-related hepatocellular carcinoma after curative resection in adults. Half of participants will receive Tenofovir disoproxil fumarate, while the other half will receive Entecavir.

  • 0 views
  • 25 May, 2020
  • 1 location