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Found 120 clinical trials
Featured trial
Chronic Heart Failure – Ages 18-85

Chronic Heart Failure – Ages 18-85

  • 170 views
  • 25 Mar, 2021
  • 1 location
Featured trial
Phase IIb Safety and Efficacy Study of Four Dose Regimens of BAY1021189 in Patients With Heart Failure With Reduced Ejection Fraction Suffering From Worsening Chronic Heart Failure (SOCRATES-REDUCED)

Phase IIb Safety and Efficacy Study of Four Dose Regimens of BAY1021189 in Patients With Heart Failure With Reduced Ejection Fraction Suffering From Worsening Chronic Heart Failure (SOCRATES-REDUCED)

  • 274 views
  • 25 Mar, 2021
  • 1 location
Featured trial
A phase III randomized, double-blind trial to evaluate efficacy and safety of once daily empagliflozin 10 mg compared to placebo, in patients with chronic Heart Failure with reduced Ejection Fraction (HFrEF).

A phase III randomized, double-blind trial to evaluate efficacy and safety of once daily empagliflozin 10 mg compared to placebo, in patients with chronic Heart Failure with reduced Ejection Fraction

  • 378 views
  • 25 Mar, 2021
  • 1 location
Featured trial
Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Skeletal Muscle Function in Heart Failure Subjects

chronic heart failure over time. This is a condition in which the heart doesn't pump blood as well as it should. Treatment of chronic heart failure has not improved much in a few decades. Researchers want

cardiopulmonary exercise testing
heart failure
systolic heart failure
chronic heart failure
radionuclide ventriculography
  • 311 views
  • 09 Apr, 2019
  • 1 location
Survival Study of the Recombinant Human Neuregulin-1β in Subjects With Chronic Heart Failure.

The purpose of this study is to evaluate efficacy of rhNRG-1 in reducing the death rate of heart failure subjects with baseline NT-proBNP level between 600 pg/ml and 1700 pg/mL and NYHA class II to III.

nt-probnp
systolic heart failure
ejection fraction
  • 43 views
  • 04 Mar, 2022
  • 64 locations
Re-evaluation of Optimal Re-synchronisation Therapy in Patients With Chronic Heart Failure (RESET-CRT)

The objective of the study is to demonstrate that in patients with chronic heart failure who receive optimal medical treatment for this condition and have indication for Cardiac

medical therapy
cardiac resynchronization therapy
ejection fraction
cardiomyopathy
  • 2 views
  • 14 May, 2022
  • 151 locations
A Study of Vericiguat (MK-1242) in Participants With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) (MK-1242-035) (VICTOR)

The purpose of this study is to evaluate the efficacy and safety of vericiguat in participants with chronic heart failure with reduced ejection fraction (HFrEF), specifically those with

  • 4 views
  • 18 May, 2022
  • 259 locations
Impact of Hypertonic Saline Solution on Acute Decompensated Heart Failure (HSS)

Acute decompensated heart failure (HF) is one of the most common cardiologic issues in emergency departments. Loop diuretics have long been recognized as the key for the treatment of Acute Decompensated Heart Failure (ADHF).However, chronic treatment with diuretics may limit their response and deteriorates the renal function. The hypertonic saline …

  • 0 views
  • 18 Apr, 2022
  • 1 location
Noninvasive Ventilation for Chronic Heart Failure

reported. This project aims to clarify the efficacy and safety of home non-invasive ventilation in patients with chronic heart failure complicated with sleep-disordered breathing. First, patients with

  • 0 views
  • 12 Sep, 2021
  • 3 locations
Tailoring Pacemaker Output to Physiology in Chronic Heart Failure

Aims: To explore the clinical effect on exercise tolerance and quality of life, safety and tolerability of pacing at higher outputs in patients with chronic heart failure and a pacemaker.

cardiopulmonary exercise testing
systolic dysfunction
dyspnea
cardiac resynchronization therapy
left ventricular systolic dysfunction
  • 0 views
  • 02 Mar, 2022
  • 1 location