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Found 106 clinical trials
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Chronic Heart Failure – Ages 18-85

Chronic Heart Failure – Ages 18-85

  • 158 views
  • 23 Nov, 2020
  • 1 location
featured
Phase IIb Safety and Efficacy Study of Four Dose Regimens of BAY1021189 in Patients With Heart Failure With Reduced Ejection Fraction Suffering From Worsening Chronic Heart Failure (SOCRATES-REDUCED)

Phase IIb Safety and Efficacy Study of Four Dose Regimens of BAY1021189 in Patients With Heart Failure With Reduced Ejection Fraction Suffering From Worsening Chronic Heart Failure (SOCRATES-REDUCED)

  • 274 views
  • 08 Nov, 2020
  • 1 location
featured
A phase III randomized, double-blind trial to evaluate efficacy and safety of once daily empagliflozin 10 mg compared to placebo, in patients with chronic Heart Failure with reduced Ejection Fraction (HFrEF).

A phase III randomized, double-blind trial to evaluate efficacy and safety of once daily empagliflozin 10 mg compared to placebo, in patients with chronic Heart Failure with reduced Ejection Fraction

  • 378 views
  • 08 Nov, 2020
  • 1 location
featured
Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Skeletal Muscle Function in Heart Failure Subjects

chronic heart failure over time. This is a condition in which the heart doesn't pump blood as well as it should. Treatment of chronic heart failure has not improved much in a few decades. Researchers want

systolic heart failure
radionuclide ventriculography
heart failure
chronic heart failure
cardiopulmonary exercise testing
  • 77 views
  • 09 Apr, 2019
  • 1 location
LTOT in COPD Patients With Moderate Chronic Hypoxemia and Chronic Heart Failure

In patients with both COPD and CHF, moderate chronic hypoxemia is caused by a combination of intrapulmonary and extrapulmonary factors. The hypothesis of this study is that adequate medical therapy for both conditions can correct the moderate hypoxemia by improving the underlying mechanisms without the need of LTOT. If this …

COPD
pulmonary disease
medical therapy
  • 31 views
  • 07 Nov, 2020
  • 1 location
Survival Study of the Recombinant Human Neuregulin-1 in Subjects With Chronic Heart Failure.

The purpose of this study is to evaluate efficacy of rhNRG-1 in reducing the death rate of heart failure subjects with baseline NT-proBNP level between 600 pg/ml and 1700 pg/mL and NYHA class II to III.

systolic heart failure
nt-probnp
ejection fraction
  • 39 views
  • 23 Jan, 2021
  • 94 locations
Re-evaluation of Optimal Re-synchronisation Therapy in Patients With Chronic Heart Failure

The objective of the study is to demonstrate that in patients with chronic heart failure who receive optimal medical treatment for this condition and have indication for Cardiac

medical therapy
cardiac resynchronization therapy
ejection fraction
cardiomyopathy
  • 2 views
  • 01 Mar, 2021
  • 346 locations
Tailoring Pacemaker Output to Physiology in Chronic Heart Failure

Aims: To explore the clinical effect on exercise tolerance and quality of life, safety and tolerability of pacing at higher outputs in patients with chronic heart failure and a pacemaker.

left ventricular systolic dysfunction
weakness
dyspnea
cardiac resynchronization therapy
cpet
  • 0 views
  • 24 Jan, 2021
  • 1 location
Limitations of Aerobic Capacity in Chronic Heart Failure

This study will use a novel CPX test that incorporates instantaneous assessment of maximal isokinetic cycling power at VO2peak to elucidate the mechanisms that limit VO2peak in CHF, and compare these responses with age-matched controls.

  • 0 views
  • 24 Jan, 2021
  • 1 location
Splanchnic Nerve Block for Therapy of Chronic Heart Failure (Splanchnic III)

Splanchnic vasoconstriction may contribute to decompensation of chronic heart failure (HF) via volume redistribution from the splanchnic vascular bed to the central compartment. This is a

  • 0 views
  • 26 Jan, 2021
  • 1 location