Found 9 clinical trials
RCT Study to Validate niPGT-A Clinical Benefit.
Chromosomal aneuploidies are linked with spontaneous miscarriages and abnormal offspring in human pregnancies. In addition, some types of aneuploidy are reported to prevent implantation. Thus, there is a need to identify the embryos with highest implantation potential on in vitro fertilization (IVF) programs. Since embryo morphology and kinetics have a …
- 717 views
- 27 Jan, 2021
- 21 locations
Embryo Selection by Noninvasive Preimplantation Genetic Test
The objective of this study is to explore whether non-invasive chromosome screening (NICS) can be used as an effective indicator for embryos selection besides morphology through a multicenter randomized controlled trial, by comparing the differences of live birth rate, pregnancy rate and miscarriage rate between the two groups of embryo …
- 0 views
- 16 May, 2021
- 13 locations
Clinical Application of Non-invasive PGT-A
The study aims to investigate the difference of in vitro fertilization (IVF) outcomes among non-invasive PGT-A, PGT-A and combined non-invasive PGT-A and PGT-A.
- 0 views
- 29 Apr, 2021
- 1 location
Non-Invasive Determination of Fetal Chromosome Abnormalities
chromosome abnormality such as Down syndrome (trisomy 21), Edward's syndrome (trisomy 18), Patau syndrome (trisomy 13), Klinefelter syndrome, (47, XXY), and other chromosome abnormalities
- 85 views
- 07 Nov, 2020
- 7 locations
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve
The study aims to explore the genetic pathogenesis of diminished ovarian reserve via whole-genome sequencing technology in Chinese women.
- 0 views
- 28 Jan, 2021
- 1 location
Chromosome 18 Clinical Research Center
treatments to help these individuals overcome the effects of their chromosome abnormality.
- 9 views
- 26 Jan, 2021
- 2 locations
Risk-stratified Therapy Based on Molecular Cytogenetic Aberration and Treatment Response in AML
Risk-stratified therapy based on molecular and cytogenetic for acute myeloid leukemia (AML) is well accepted and benefits patients' survival. However, neither every patient with low risk factors obtains better survival, nor all high risk patients experience worse outcome. Lots of data have shown that the early treatment response presenting as …
- 1 views
- 23 Jan, 2021
- 1 location
Multi-center Study to Validate niPGT-A
Abnormal chromosome number, or aneuploidy, is common in human embryos. It is responsible for more than half of all miscarriages, and it is the leading cause of congenital birth defects. Besides, it has been described that aneuploidy may also affect embryo implantation. Therefore, selecting embryos that have the best chance …
- 1113 views
- 29 Jan, 2021
- 12 locations
Diagnosis and Management of Intrauterine Growth Restriction and Congenital Anomalies
The purpose of this prospective cohort study is to build a large platform that includes clinical information (prenatal diagnosis and postnatal follow-up data) and biological specimen banks of fetuses/infants with IUGR or congenital anomalies, which provide vital support and research foundation for accurate diagnosis, precision treatment and meticulous management.
- 5 views
- 22 Jan, 2021
- 1 location