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Found 8 clinical trials
RCT Study to Validate niPGT-A Clinical Benefit.

Chromosomal aneuploidies are linked with spontaneous miscarriages and abnormal offspring in human pregnancies. In addition, some types of aneuploidy are reported to prevent implantation. Thus, there is a need to identify the embryos with highest implantation potential on in vitro fertilization (IVF) programs. Since embryo morphology and kinetics have a …

embryo culture
in vitro fertilization
intracytoplasmic sperm injection
  • 27 Jan, 2021
  • 21 locations
Clinical Application of Non-invasive PGT-A

The study aims to investigate the difference of in vitro fertilization (IVF) outcomes among non-invasive PGT-A, PGT-A and combined non-invasive PGT-A and PGT-A.

  • 29 Apr, 2021
  • 1 location
Non-Invasive Determination of Fetal Chromosome Abnormalities

chromosome abnormality such as Down syndrome (trisomy 21), Edward's syndrome (trisomy 18), Patau syndrome (trisomy 13), Klinefelter syndrome, (47, XXY), and other chromosome abnormalities

  • 07 Nov, 2020
  • 7 locations
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve

The study aims to explore the genetic pathogenesis of diminished ovarian reserve via whole-genome sequencing technology in Chinese women.

  • 28 Jan, 2021
  • 1 location
Chromosome 18 Clinical Research Center

treatments to help these individuals overcome the effects of their chromosome abnormality.

  • 26 Jan, 2021
  • 2 locations
Risk-stratified Therapy Based on Molecular Cytogenetic Aberration and Treatment Response in AML

Risk-stratified therapy based on molecular and cytogenetic for acute myeloid leukemia (AML) is well accepted and benefits patients' survival. However, neither every patient with low risk factors obtains better survival, nor all high risk patients experience worse outcome. Lots of data have shown that the early treatment response presenting as …

chromosomal abnormalities
myeloid leukemia
  • 23 Jan, 2021
  • 1 location
Multi-center Study to Validate niPGT-A

Abnormal chromosome number, or aneuploidy, is common in human embryos. It is responsible for more than half of all miscarriages, and it is the leading cause of congenital birth defects. Besides, it has been described that aneuploidy may also affect embryo implantation. Therefore, selecting embryos that have the best chance …

embryo culture
in vitro fertilization
embryo transfer
intracytoplasmic sperm injection
  • 29 Jan, 2021
  • 12 locations
Diagnosis and Management of Intrauterine Growth Restriction and Congenital Anomalies

The purpose of this prospective cohort study is to build a large platform that includes clinical information (prenatal diagnosis and postnatal follow-up data) and biological specimen banks of fetuses/infants with IUGR or congenital anomalies, which provide vital support and research foundation for accurate diagnosis, precision treatment and meticulous management.

intrauterine growth retardation
  • 22 Jan, 2021
  • 1 location