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Found 4 clinical trials
Phase 2 Trial to Evaluate Safety and Efficacy of AU-011 Via Suprachoroidal Administration in Subjects With Primary Indeterminate Lesions and Small Choroidal Melanoma

The primary objective is to assess safety and efficacy of AU-011 via suprachoroidal injection to treat primary indeterminate lesions and small choroidal melanoma.

choroid melanoma
  • 22 Apr, 2022
  • 18 locations
Adjuvant Sunitinib or Valproic Acid in High-Risk Patients With Uveal Melanoma

This randomized phase II trial studies how well sunitinib malate or valproic acid works in preventing high-risk uveal (eye) melanoma from spreading to other parts of the body. Sunitinib malate may stop the transmission of growth signals into tumor cells and prevents these cells from growing. Valproic acid may change …

  • 24 Jan, 2022
  • 1 location
Prospective Matched Case-Control Study With AU-011 or Plaque Radiotherapy for Primary Indeterminate Lesions or Choroidal Melanoma (IL/ CM) (IL)

This is a prospective multicenter, matched case-control study of patients with primary indeterminate lesions or choroidal melanoma who receive treatment with AU-011 and patients who are planned to receive standard of care (SOC) treatment with plaque radiotherapy (plaque) to compare the visual outcomes of AU-011 and plaque radiotherapy.

  • 29 Jun, 2022
  • 4 locations
A Registry of Patients With Primary Indeterminate Lesions or Choroidal Melanoma

The purpose of this observational research study is to follow participants who have been treated with either AU-011 or observation and/or received standard of care therapy while participating in a previous Aura Biosciences clinical research study to assess the long-term safety and effectiveness of AU-011 and standard of care therapy. …

  • 04 Jun, 2022
  • 14 locations