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Found 24 clinical trials
Image Assisted Optimization of Proton Radiation Therapy in Chordomas and Chondrosarcomas (CHIPT)

Rationale: Chordomas and chondrosarcomas located in the axial skeleton are malignant neoplasms of bone. These tumors share the same clinical challenges, as the effect of the disease is more a

proton therapy
  • 20 Apr, 2022
  • 2 locations
Genetic Clues to Chordoma Etiology: A Protocol to Identify Sporadic Chordoma Patients for Studies of Cancer-Susceptibility Genes

essential for formation and maintenance of the notochord. Some of the other chordoma families that we studied did not have T-gene duplications; the aggregation of chordomas in these families may result from

  • 19 Sep, 2022
  • 1 location
Assessing Pediatric Endpoints in DM1 (ASPIRE-DM1) (ASPIRE-DM1)

The overall goal of the study is to establish valid clinical endpoint assessments for children with congenital myotonic dystrophy type 1 and childhood myotonic dystrophy type 1, and develop biomarkers for the condition.

myotonic dystrophy
  • 18 Sep, 2022
  • 1 location
Comparing Carbon Ion Therapy, Surgery, and Proton Therapy for the Management of Pelvic Sarcomas Involving the Bone, the PROSPER Study

This study compares carbon ion therapy, surgery, and proton therapy to determine if one has better disease control and fewer side effects. There are three types of radiation treatment used for pelvic bone sarcomas: surgery with or without photon/proton therapy, proton therapy alone, and carbon ion therapy alone. The purpose …

soft tissue sarcoma
proton therapy
cancer chemotherapy
  • 18 Jun, 2022
  • 3 locations