Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 26 clinical trials
Ion Irradiation of Sacrococcygeal Chordoma

The purpose of this study is to evaluate the safety and feasibility of primary hypofractionated irradiation of sacrococcygeal chordoma with carbon ions or protons using the raster scan technique

  • 4 views
  • 05 Sep, 2021
  • 1 location
Sacral Chordoma: Surgery Versus Definitive Radiation Therapy in Primary Localized Disease (SACRO)

Comparative study on surgery versus definitive radiation therapy in primary localized sacral chordoma

ct scan
proton therapy
antineoplastic
  • 71 views
  • 25 Feb, 2022
  • 12 locations
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

>Desmoid tumors Peripheral nerve sheath tumors and NF1-related tumors (closed to accrual 09/19/2018) Malignant giant cell tumors Chordoma (closed to accrual 11/29/2018)

carcinoid
chordoma
ipilimumab
amylase
adenocarcinoma
  • 6634 views
  • 10 Aug, 2022
  • 752 locations
Pemetrexed for the Treatment of Chordoma

The purpose of this study is to test the safety and tolerability of pemetrexed administered to people with chordoma. Other purposes of this study are to: find out side effects

  • 0 views
  • 27 Jan, 2021
  • 1 location
CDK4/6 Inhibition in Locally Advanced/Metastatic Chordoma

In chordoma cell lines and patient biopsies, the p16 (CDKN2A) tumor suppressor is consistently deleted. Thus, chordomas are an example of a tumor with universal activation of the cyclin

cancer chemotherapy
vasectomy
imatinib
palbociclib
sorafenib
  • 39 views
  • 07 Jan, 2022
  • 3 locations
Nivolumab and Relatlimab in Treating Participants With Advanced Chordoma

This phase II trial studies how well nivolumab and relatlimab work in treating participants with chordoma that has spread to other places in the body. Monoclonal antibodies, such as nivolumab

relatlimab
nivolumab
absolute neutrophil count
gonadotropin
vasectomy
  • 12 views
  • 15 May, 2022
  • 1 location
Cetuximab for the Treatment of Advanced Unresectable or Metastatic Chordoma

This is a multicenter, single arm, phase 2 study designed to evaluate the efficacy and safety of cetuximab for the treatment of advanced (unresectable)/metastatic, chordoma. The target patient

absolute neutrophil count
ct scan
pet/ct
x-rays
renal function
  • 0 views
  • 18 Jun, 2022
  • 1 location
Trial of Proton Versus Carbon Ion Radiation Therapy in Patients With Chordoma of the Skull Base

This study is a prospective randomised clinical phase III trial. The primary objective of this study is to evaluate, if the innovative therapy (carbon ion irradiation) in chordomas is superior

proton therapy
innovative therapy
  • 47 views
  • 08 Nov, 2020
Randomized Carbon Ions vs Standard Radiotherapy for Radioresistant Tumors (ETOILE)

macroscopically uncompleted resected radioresistant tumors. Eligible tumors are axial chordoma (except of base of skull), adenoid cystic carcinoma of head and neck (except of trachea) and sarcomas of any site

  • 23 views
  • 28 Feb, 2022
  • 10 locations
Talimogene Laherparepvec, Nivolumab and Trabectedin for Sarcoma (TNT)

This is a Phase 2 study using talimogene laherparepvec, nivolumab, and trabectedin as first, second or third line therapy for advanced sarcoma, including desmoid tumor and chordoma.

advanced sarcoma
kidney function tests
trabectedin
metastatic sarcoma
platelet count
  • 37 views
  • 08 Feb, 2022
  • 1 location