Found 35 clinical trials
Acute Choline Supplementation and Cardiovascular Health in Adults
Trimethylamine-N-oxide (TMAO), a metabolite produced by gut microbial metabolism of dietary choline, has recently been causally linked to atherosclerosis in animal models and has been shown to
- 94 views
- 25 Oct, 2022
- 1 location
Short Term Choline Supplementation and Cardiometabolic Health in Adults
Trimethylamine-N-oxide (TMAO), a metabolite produced by gut microbial metabolism of dietary choline, has recently been causally linked to atherosclerosis in animal models and has been shown to
- 0 views
- 20 Oct, 2022
- 1 location
Effects of Increased Maternal Choline Intake on Child Cognitive Development
The purpose of this study is to examine cognitive and affective outcomes in the offspring of women supplemented with choline vs. control during pregnancy.
- 0 views
- 22 Mar, 2022
- 1 location
Pilot Trial of Spectroscopic MRI-guided, Dose-Escalated Proton Radiation Therapy and Bevacizumab for Recurrent Glioblastoma
The purpose of this research is to find hidden cancer with an experimental magnetic resonance imaging (MRI) scan called spectroscopic magnetic resonance imaging (sMRI). That spectroscopic MRI scan will be used to increase the area of the brain receiving radiation and then the dose of radiation in attempt to kill …
- 0 views
- 27 Oct, 2022
- 1 location
Donepezil Versus Non-drug Treatment in Alzheimer's Disease. (CHOLINE-2)
Donepezil, as well as the other symptomatic drugs of Alzheimer's disease, is not any more reimbursed by the French healthcare system, due to a controversy about its efficiency. French health authorities currently preconize a non-rug approach based on cognitive remediation or stimulation. The aim of this study is to compare …
- 0 views
- 26 Mar, 2022
Efficacy and Safety of ChOline ALfoscerate in Patient With Mild to Moderate Alzheimer's Disease (COALA)
The purpose of this study is to determine whether combination of donepezil, a cholinesterase inhibitor, with choline alfoscerate has a more favourable clinical profile than monotherapy with
- 0 views
- 08 Jun, 2022
- 3 locations
PEACE V: Salvage Treatment of OligoRecurrent Nodal Prostate Cancer Metastases (STORM)
in number (oligorecurrence) using choline or PSMA PET-CT. As there are no specific treatment recommendations for these type of patients, different treatment approaches are currently used, mostly
- 216 views
- 04 Mar, 2022
- 29 locations
Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Using PET/CT Imaging
This phase III trial compares the addition of apalutamide, with or without targeted radiation therapy, to standard of care treatment versus standard of care treatment alone in patients with prostate cancer biochemical recurrence (a rise in the blood level of prostate-specific antigen [PSA] after treatment with surgery or radiation). Diagnostic …
- 0 views
- 27 May, 2022
- 21 locations
Effects of Complementary Feeding of Eggs on Infant Development and Growth in Guatemala: The Saqmolo Study
The specific aims of this study are: In a randomized controlled trial, the investigators will evaluate the impact of daily egg consumption during the complementary feeding period in addition to the local standard of nutrition care (i.e., intervention group), compared to the local standard of nutrition care alone (i.e., control …
- 0 views
- 16 Jul, 2021
- 1 location
Choline Supplementation as a Neurodevelopmental Intervention in Fetal Alcohol Spectrum Disorders Study
This is a randomized, double-blind controlled trial of choline supplementation in children with Fetal Alcohol Spectrum Disorders (FASD). The study is comparing two administration durations (3
- 0 views
- 07 Dec, 2021
- 1 location