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Found 12 clinical trials
Featured trial
ODYSSEY OUTCOME STUDY - A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Effect of SAR236553/REGN727 on the Occurrence of Cardiovascular Events in Patients Who Have Recently Experienced an Acute Coronary Syndrome

ODYSSEY OUTCOME STUDY - A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Effect of SAR236553/REGN727 on the Occurrence of Cardiovascular Events in Patients Who Have Recently Experienced an Acute Coronary Syndrome

  • 100 views
  • 25 Mar, 2021
  • 1 location
Effects of Ezetimibe Combination Therapy for Patients With Atherosclerotic Cardiovascular Disease; Randomized Comparison of LDL-cholesterol Targeting <70 Versus <55mg/dL; Ez-PAVE Trial

be an alternative strategy not only to lower LDL-cholesterol level and also to reduce the need of dosage of high-intensity statin to achieve sufficient LDL-cholesterol lowering effect. However

  • 0 views
  • 21 Jun, 2021
  • 1 location
RAndomized Comparison of Efficacy and Safety of Lipid-lowerING With Statin Monotherapy Versus Statin/Ezetimibe Combination for High-risk Cardiovascular Diseases (RACING Trial)

in patients with inadequate lowering LDL-cholesterol level. Additive ezetimibe will also an alternative strategy not only to lower LDL-cholesterol level and also to reduce the need of dosage of high

ezetimibe
arteriopathy
cholesterol measurement
hmg-coa reductase inhibitor
cardiovascular disease
  • 13 views
  • 25 Feb, 2022
  • 1 location
Low Dose Rosuvastatin Plus Ezetimibe Versus High-dose Rosuvastatin in AMI (ROSUZET-AMI)

Combination therapy of rosuvastatin 5mg and ezetimibe 10 mg showed similar achievement rate in decreasing LDL cholesterol level by 50% as single use of rosuvastatin 20 mg. This trial aims

myocardial infarction
infarct
acute myocardial infarction
percutaneous coronary intervention
  • 0 views
  • 07 Oct, 2022
  • 7 locations
Advancing Cardiac Care Unit-based Rapid Assessment and Treatment of hypErcholesterolemia (ACCURATE)

endpoints will be the proportion of patients who undergo intensification of lipid-lowering therapy, the lowest LDL cholesterol level achieved, and the proportion of patients reaching guideline recommended

lipid-lowering therapy
acute coronary syndrome
LDL Cholesterol
cholesterol level
genetic analysis
  • 0 views
  • 23 Mar, 2022
  • 1 location
Post Approval Study of Liposorber LA-15 System for the Treatment of Focal Segmental Glomerulosclerosis in Children (FSGS pediatric)

plasma cholesterol level. The system was originally developed for the treatment of patients with serious dyslipidemia such as familial hypercholesterolemia and then applied to improve the dyslipidemia, a

primary focal segmental glomerulosclerosis
nephrotic syndrome
low density lipoprotein
proteinuria
corticosteroids
  • 36 views
  • 20 Apr, 2022
  • 10 locations
Cardiovascular Risk Assessment for Patients With Rheumatoid Arthritis Arthritis: (CARE RA)

patients. This will consist of patient education and a decision support program to facilitate screening for hyperlipidemia (high cholesterol level) or initiation of medications to lower cholesterol

cholesterol measurement
hmg-coa reductase inhibitor
cardiovascular disease
hmg-coa reductase inhibitors
remission
  • 0 views
  • 24 Mar, 2022
  • 1 location
Usual Dose Rosuvastatin Plus Ezetimibe Versus High-dose Rosuvastatin on Coronary Atherosclerotic Plaque

The aim of this prospective, open-label, randomized, single center study is to compare the effect of usual dose rosuvastatin plus ezetimibe and high-dose rosuvastatin on modifying atherosclerotic plaque.

intravascular ultrasound
ezetimibe
heart disease
rosuvastatin
stenosis
  • 10 views
  • 18 Nov, 2021
  • 1 location
Brain Boosters 2 in Persons at Risk for Alzheimer's Disease: a Digital Application Supported Intervention (BB2)

The purpose of this research is to determine if training in memory support aids and healthy lifestyle activities (physical exercise, mentally stimulating activities and stress management) can have a positive effect on memory, thinking, and activities that people do every day. Participation in this study will involve being placed into …

  • 3 views
  • 23 Mar, 2022
  • 1 location
Effect of PCSK9 Inhibition on Cardiovascular Risk in Treated HIV Infection (EPIC-HIV Study) (EPIC-HIV)

Atherosclerosis in the setting of HIV infection is distinct and includes increased vascular inflammation, worsened endothelial function, and a predominance of non-calcified plaque. These outcomes can be assessed using specialized noninvasive imaging which strongly predict future CV events in the general population. PCSK9 has emerged as an important pharmacologic target …

immune globulin
type 2 diabetes mellitus
arteriopathy
cholesterol measurement
hiv-1 rna measurement
  • 17 views
  • 09 May, 2022
  • 1 location