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Found 14 clinical trials
Hydroxychloroquin (HCQ) in chILD of Genetic Defect

The purpose of this proposed research is to investigate the efficacy and safety of hydroxychloroquine sulfate (HCQ, Quensyl) for pediatric ILD(chILD) caused by pulmonary surfactant-associated genes mutations.

  • 0 views
  • 27 Feb, 2022
  • 1 location
Partial Brain RT, Temozolomide, Chloroquine, and TTF Therapy for the Treatment of Newly Diagnosed Glioblastoma

This trial studies the side effects of partial brain radiation therapy, temozolomide, chloroquine, and tumor treating fields therapy for the treatment of newly diagnosed glioblastoma. Radiation

neutrophil count
MRI
gliosarcoma
bilateral tubal ligation
temozolomide
  • 0 views
  • 23 May, 2022
  • 1 location
Safety and Tolerability of Chlorquine in Addition to Anti-tuberculosis Therapy

In vitro and in vivo data show promising results of adjunctive use of Chloroquine to standard tuberculosis therapy as Chloroquine enhances animicrobial effectiveness against intracellular MTB

Accepts healthy volunteers
  • 0 views
  • 27 Jul, 2022
  • 1 location
Taste Physiology in Obese Volunteers Before and After Bariatric Surgery

glucose, monosodium glutamate, chloroquine and placebo is followed by functional brain MRI in obese humans before and 3 months after surgery.

bariatric surgery
  • 24 views
  • 10 Oct, 2021
  • 1 location
Safety and Efficacy of Different Regimens of Primaquine on Vivax Malaria Treatment in G6PD Deficient Patients

patients with P. vivax monoinfection will be treated with either weekly or delayed one-week course of primaquine, and the currently recommended by national guideline, 12-week chloroquine regimen to compare

g6pd deficiency
primaquine
hemolysis
chloroquine
glucose-6-phosphate dehydrogenase
  • 37 views
  • 12 Apr, 2022
  • 2 locations
International Cooperative Phase III Trial of the HIT-HGG Study Group (HIT-HGG-2013) (HIT-HGG-2013)

investigate the therapeutic efficiency and safety of valproic acid and the autophagy inhibitor chloroquine, both in addition to temozolomide therapy. Since distribution of Resochin junior (chloroquine

glioblastoma multiforme
malignant glioma
astrocytoma
anaplastic astrocytoma
temozolomide
  • 44 views
  • 16 Jun, 2022
  • 46 locations
Novel Regimens in COVID-19 Treatment

Nitazoxanide has been shown to have a clinical efficacy against severe acute respiratory syndrome coronavirus 2; ivermectin has also demonstrated a remarkable experimental efficacy with a potential to be used for Coronavirus disease 2019.

  • 4 views
  • 27 Jan, 2021
  • 2 locations
Vivax Malaria Human Infection Studies in Thailand (MIST1)

This study is a human challenge study to assess the feasibility and safety of controlled human malaria infection (via P. vivax sporozites) in healthy volunteers, and to develop a bank of P. vivax-infected blood for use in future controlled human P. vivax malaria infection studies. Additional objectives are to obtain …

Accepts healthy volunteers
  • 0 views
  • 15 Jun, 2022
  • 1 location
Masitinib in Patients With Symptomatic Mild to Moderate COVID-19

The objective of the study is to evaluate the anti-viral efficacy of 3 different dosages of masitinib in patients with symptomatic mild to moderate COVID-19.

  • 0 views
  • 10 Jul, 2022
  • 5 locations
A Controlled Human Vivax Malaria Infection Study Through Inoculation of Infected Erythrocytes (MIST2)

The primary objectives of this study are to assess the safety and feasibility of blood-stage controlled human P. vivax malaria infection (CHMI) in healthy adult Thai volunteers through experimental injection of cryopreserved P. vivax infected erythrocytes, and to choose the optimal inoculation dose for future P. vivax CHMI studies. In …

Accepts healthy volunteers
  • 0 views
  • 14 Jul, 2022
  • 1 location