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Found 44 clinical trials
Brief Intervention to Reduce STDs in ER Drug Users - 1

The purpose of this study is to test whether a brief motivational interview focused on sexual practices will facilitate behavior change, risk reduction and reduced rate of sexually transmitted infections among emergency department patients who use heroin and cocaine and are out-of-treatment for their substance abuse.

motivational interviewing
heroin
  • 48 views
  • 07 Nov, 2020
  • 1 location
A Phase II Randomized, Observer-Blind, Placebo-Controlled Study, to Assess the Efficacy of Meningococcal Group B Vaccine rMenB+OMV NZ (Bexsero) in Preventing Gonococcal Infection

This is a Phase II, randomized, observer-blind, placebo-controlled, multi-site trial of the FDA licensed rMenB+OMV NZ vaccine, Bexsero. The targeted study population is men and women 18-50 years of age who are disproportionately vulnerable to N. gonorrhoeae infection. Approximately 2,200 participants are expected to be enrolled to achieve at least …

Accepts healthy volunteers
  • 107 views
  • 21 Oct, 2022
  • 7 locations
Genital CT Treatment to Pregnant Women to Prevent Adverse Pregnancy Outcomes: A Pilot RCT (RCT)

This study aims to identify the relationship between genital C. trachomatis and adverse pregnancy outcomes, and investigate whether screening and treatment of genital C. trachomatis in pregnant women can reduce adverse pregnancy outcomes. Approximately 200 pregnant women from Nanhai Hospital of Southern Medical University in Guangzhou, China will be enrolled …

Accepts healthy volunteers
  • 0 views
  • 10 Mar, 2022
  • 1 location
Cervical Occlusion Two-level Stitch Application (COSA)

Cervical insufficiency is defined as painless dilatation of the cervix during the second trimester of pregnancy. As a result of shortening and opening of the cervix, despite the lack of uterine contractions, the fetal membranes invade into the cervical canal and then into the vagina, which results in premature rupture …

  • 0 views
  • 04 Oct, 2022
  • 4 locations
Antibacterial Mouthwash for Pharyngeal Gonorrhea Prevention

This study aims to determine acceptability and preliminary efficacy of daily use of an antibacterial mouthwash as compared to a placebo mouthwash in reducing the incidence of pharyngeal gonorrhea among a cohort of HIV-positive and high risk HIV-negative men. Investigators plan to test the following hypotheses: Participants will maintain a …

  • 0 views
  • 17 Jun, 2022
  • 1 location
Εffectiveness of Intrauterine Antibiotic Administration for Treatment of Chronic Endometritis

Chronic Endometritis (CE) is related to infertility and entails a challenging management. This study investigates the treatment of off-label intrauterine antibiotic infusion either separately or combined with oral antibiotic administration, and it assesses respective performance against the gold standard treatment of oral antibiotic adminstration. Data sourced herein reports on treatment …

  • 0 views
  • 23 Mar, 2022
  • 1 location
Vaginal Microbiota Transplant (MOTIF)

This is a randomized trial of vaginal microbiome transplant vs. saline placebo to restore a Lactobacillus dominant vaginal microbial community in women with recurrent bacterial vaginosis.

  • 1 views
  • 28 Feb, 2022
Efficacy of Transvaginal Ultrasound-guided Aspiration for Treatment of Tubo-ovarian Abscess Compared With Laparoscopy (Pactol)

"Tubo-ovarian abscess (TOA) include pyosalpinx, ovarian abscess, tubo-ovarian abscess and Douglas abscess. The only randomized study evaluating TOA treatment reported a higher cure rate (90 versus 65%) when antibiotic therapy is associated with abscess evacuation. TOA evacuation can be performed by surgery or by drainage. No studies have compared success …

  • 0 views
  • 04 Oct, 2022
  • 1 location
Expedited Partner Therapy and the HIV Prevention Cascade (EPT and MSM)

> Expedited Partner Therapy (EPT) has been shown to reduce rates of persistent or recurrent gonorrhea and chlamydia infection in heterosexual patients, but has not been fully evaluated for use

  • 0 views
  • 03 Jun, 2022
  • 1 location
Adolescent Sexually Transmitted Infection Screening in the Emergency Department (STI)

our recent insights obtained from single center ED-based adolescent gonorrhea and chlamydia screening research and apply them across a national pediatric ED research network to determine the most

gonorrhea
Accepts healthy volunteers
sexually transmitted disease
targeted screening
chlamydial infection
  • 95 views
  • 04 Oct, 2022
  • 1 location