Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 617 clinical trials
Analysis of Circulating Tumor Markers in Blood (ALCINA 2)

The circulating tumoral biomarkers in the blood are the object of numerous researches for several decades. The potential clinical interests of these circulating biomarkers are diagnostic, prognostic, predictive of the efficiency of targeted therapies (according to the mutational profile of the cancer), and could allow the study of the mechanisms …

primary cancer
tumor markers
  • 2 views
  • 12 Feb, 2022
  • 2 locations
EXOME Analysis Position in the Strategy of Genetic Predisposition Factors Identification in Early-onset Cancer (EX²TRICAN)

5 to 10% of cancers are due to the presence of a constitutional genetic alteration. It can be inherited from parents (family form) or by accident, in the first moments of life after fertilization (sporadic form). In both cases, this genetic alteration is constitutional and transmissible to descendants. It is …

primary cancer
breast cancer
  • 0 views
  • 15 Feb, 2022
  • 1 location
Development of a Clinical and Biological Database in Peritoneal Carcinosis (BCB CARCINOSE) (BCB)

The creation of a prospective clinical-biological base dedicated to peritoneal carcinosis must therefore be able to serve as a support for this essential search for transfer.

primary cancer
  • 2 views
  • 21 Mar, 2022
  • 1 location
The Drug Rediscovery Protocol (DRUP Trial) (DRUP)

This is a prospective, non-randomized clinical trial that aims to describe the efficacy and toxicity of commercially available, targeted anticancer drugs* prescribed for treatment of patients with advanced cancer with a potentially actionable variant as revealed by a genomic or protein expression test. The study also aims to simplify patient …

advanced cancer
bevacizumab
solid neoplasm
trastuzumab
lymphoma
  • 266 views
  • 27 Jan, 2022
  • 35 locations
OncoSNIPE - Study of Molecular Profiles Associated With the Development of Resistance in Solid Cancer Patients

Precision medicine is considered to be one of the major issues in patient care. A lot of research has already proven itself with the implementation of targeted therapies including immunotherapies offering patients improved response and survival rates. But despite these major therapeutic advances, resistance to anti-cancer treatment is a major …

HER2
breast cancer
adenocarcinoma
targeted therapy
estrogen
  • 0 views
  • 18 Sep, 2021
  • 11 locations
Genetic Testing in Young Adults With Cancer Study

The overarching goal of our research is to define an evidence-based, sustainable approach to identifying and managing genetic risk among young adults with cancer and their relatives. Conventional practice leaves referral and testing decisions to mostly non-expert clinicians implementing complex guidelines at the point of care, leading to substantial under-utilization. …

cancer diagnosis
primary cancer
solid tumor
genetic testing
  • 0 views
  • 20 Oct, 2021
  • 1 location
IMPACt of an Enhanced Screening Program on the Detection of Non-AIDS NEOplasms in HIV Patients

Introduction: The incidence of malignancies is higher in the HIV-infected population than in the general population, and it is already one of the leading causes of death in people living with the virus. It is estimated that the situation will be aggravated by the progressive aging of the HIV-infected population. …

  • 0 views
  • 15 Feb, 2021
  • 1 location
Bilingual Electronic Symptom Management Program Across Multi-site Comprehensive Cancer Center

Cancer, and cancer treatment, cause many symptoms that can negatively affect quality of life. Despite the development of improved symptom management interventions and several evidenceand consensus-based guidelines, their timely delivery remains uneven in the health care system. Our research center, Northwestern University IMPACT (NU IMPACT), builds upon an electronic health …

  • 0 views
  • 10 Mar, 2021
  • 1 location
Evaluating the Use of Patient-Reported Outcome Measures for Improving the Inter-Rater Reliability of Common Terminology Criteria for Adverse Event Ratings

This open randomized trial investigates, if clinicians complete CTCAE ratings differently when receiving patients' patient-reported outcome (PRO) data prior to their CTCAE completion. The primary objective is to demonstrate superior inter-rater reliability of CTCAE ratings from physicians relying on EORTC PRO data as additional data source over traditional CTCAE ratings …

cancer diagnosis
primary cancer
  • 0 views
  • 22 Apr, 2022
  • 1 location
Exome Analysis (Complexe vs Simple) to Help the Therapeutic Decision for the Precision Medicine (EXOMA2)

The "simple" analysis of the exome can determine somatic and constitutional mutations. The major challenge lies in the translation of sequencing data into clinically relevant information allowing the clinician to guide his decision-making A "complex" analysis of the exome would provide access to structural DNA data, concerning mutational signatures, tumor …

solid tumor
  • 0 views
  • 24 Apr, 2022
  • 1 location