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Found 10 clinical trials
Pleural Irrigation With Normal Saline Versus Intrapleural Fibrinolytic (PENTAD-FT)

Parapneumonic effusions caused by an infection of the pleural membranes occur in 40-57% of cases of pneumonia. A variable percentage (10-20%) of parapneumonic effusions progresses to empyema (pus) and/or abscess formation (encapsulation). Pleural infection is associated with significant morbidity and mortality which may be as high as 20-35% in immunocompromised …

Accepts healthy volunteers
  • 12 Sep, 2023
  • 1 location
Role of Toilet Bronchoscopy in RICU

the procedure and when air-bronchograms are not present at the chest radiograph. It is also beneficial when there is an indication to reverse lobar atelectasis, rather than simply to remove

chronic obstructive pulmonary disease
  • 20 Aug, 2023
  • 1 location
Comparing Different Sizes of Small-bore Chest Drains in Malignant Pleural Effusion

Malignant pleural effusion (MPE) is a very common medical condition, especially among patients with disseminated cancers. Chest drain insertion aims to drain the pleural fluid collection and relieve dyspnea. Small bore chest tubes are recommended as the first line therapy for draining pleural effusions. However, there is no clinical data …

Accepts healthy volunteers
  • 24 May, 2022
  • 1 location
CCCG-HD-2018 for Children and Adolescents With Newly Diagnosed Hodgkin Lymphoma

The incidence of Hodgkin's lymphoma (HL) in Chinese children and adolescents is only 1 / 10 of that in Europe and the United States, which is a "rare" childhood tumor. Due to the "drug shortage" and extremely low incidence, it has brought great difficulties to the domestic clinical research and …

  • 13 Sep, 2023
  • 3 locations
The Management of Traumatic Hemothoraces (HemoTxRCT)

Chest injuries are common in patients with polytrauma and are responsible for approximate 25% of all trauma-related mortalities. Traumatic injuries to the thorax often result in the accumulation of blood within the chest (i.e. a hemothorax (HTX)). The management of HTX remains a clinical dilemma when the volume of blood …

conservative management
  • 03 Mar, 2022
  • 2 locations
Study of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in Fetuses With Severe Left Congenital Diaphragmatic Hernia (CDH) (FETO)

Despite advances in prenatal diagnosis and postnatal therapies, including extracorporeal membrane oxygenation (ECMO), inhaled nitric oxide therapy, and ventilator strategies that minimize ventilator-induced lung injury, morbidity and mortality rates for babies with congenital diaphragmatic hernia (CDH) remain high. The survival relates to the degree of prenatal lung compression and the …

fetal therapy
nitric oxide
nitric oxide therapy
e 25
  • 21 Oct, 2022
  • 1 location
Usefulness of White Blood Cell Count (WBCC) During Infection in Geriatric Patient

In the general population, increased WBCC and neutrophil count are widely used as markers for infection during inflammatory states 1. However, 32% of geriatric patients with an infection do not develop an increase in WBCC 2. The hypothesis is that with inflammation, geriatric patients have a misadapted response of the …

  • 16 Dec, 2021
  • 1 location
Shanghai Older People Cohort Establishment and Follow-up

Our objective is to establish a natural population cohort in East China based on the latest scientific researches, preliminary findings of the project team, and a close cooperation model of the Specialist Medical Consortium. Firstly, we will focus on the information and management status of high-risk, single-patient, and co-occurring patient …

coronary disease
heart disease
  • 25 Jan, 2021
  • 1 location
Evaluation of Pneumoconiosis High Risk Early Warning Models

Precaution of pneumoconiosis is more important than treatment. However, the current process can't early warn the high-risk dust exposed workers until they are diagnosed with pneumoconiosis. With the feature of efficiency, impersonality and quantification, artificial intelligence is just appropriate for solving this problems. Therefore, we are aiming at adapting deep …

chest x-ray
  • 19 Jul, 2021
  • 1 location
Diaphragmatic Motion Using Linear Ultrasound

This study evaluates the movement of the diaphragm (which is the main muscle used for breathing). It will compare two ultrasound modalities: linear ultrasound versus curvilinear ultrasound, at measuring diaphragm motion. The proposed measurement method with linear ultrasound is novel, and will be compared against the established method with curvilinear …

  • 19 Sep, 2023
  • 1 location