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Found 164 clinical trials
Testing the Combination of MLN4924 (Pevonedistat) Carboplatin and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With Immunotherapy

growth of cancer cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as carboplatin and paclitaxel, work in different ways to stop the growth of cancer cells, either by

antiretroviral therapy
periodic abstinence
paclitaxel
targeted therapy
lactational amenorrhea
  • 1 views
  • 27 Jan, 2021
  • 4 locations
Intrathecal Rituximab With Standard Intrathecal Prophylaxis to Prevent CNS Relapse for CD 20+ Non Hodgkin Lymphoma

The purpose of this research study is to learn if giving rituximab, the study drug, right into the spinal canal along with chemotherapy drugs like methotrexate is possible and safe.

methotrexate
chop regimen
chemotherapy drugs
large b-cell lymphoma
b-cell lymphoma
  • 1 views
  • 23 Jan, 2021
  • 1 location
Study of Chemoimmunotherapy for High-Risk Neuroblastoma

The purpose of this study is to find out whether an experimental drug called Hu3F8 can be given with the chemotherapy drugs irinotecan and temozolomide and another drug called GM-CSF. The

high-risk neuroblastoma
mycn protein
temozolomide
monoclonal antibody ch14.18
hu3f8
  • 30 views
  • 26 Jan, 2021
  • 1 location
Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Metastatic Triple-negative Breast Cancer

to give higher doses of chemotherapy drugs and kill more tumor cells.

breast cancer
abraxane
tumor cells
immunohistochemistry
estrogen
  • 76 views
  • 24 Jan, 2021
  • 1 location
Transplantation Using Reduced Intensity Approach for Patients With Sickle Cell Disease From Mismatched Family Donors of Bone Marrow

-matched related donors. Preparation before transplant includes the chemotherapy drugs hydroxyurea, fludarabine, thiotepa, anti-thymocyte globulin, and cyclophosphamide. It also includes radiation.

iron
acute chest syndrome
blood transfusion
hypertension
asthma
  • 33 views
  • 13 Feb, 2021
  • 1 location
A Study of Two Dosing Schedules of Atezolizumab in Combination With Gemcitabine and Cisplatin as First-Line Treatment for Metastatic Bladder Cancer

The purpose of this study is to compare any good and bad effects the study drug atezolizumab has on the cancer when combined with the standard chemotherapy drugs gemcitabine and cisplatin (or GC

cancer
atezolizumab
warfarin
gemcitabine
metastatic bladder cancer
  • 44 views
  • 27 Jan, 2021
  • 16 locations
A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or Leg

The purpose of this study is to find out whether giving the study drug pembrolizumab in combination with the chemotherapy drugs melphalan and dactinomycin, delivered directly to the affected arm

advanced sarcoma
cancer chemotherapy
neutrophil count
alveolar soft part sarcoma
dactinomycin
  • 0 views
  • 05 Feb, 2021
  • 7 locations
Whole Body Vibration for the Improvement of Health and Functioning in Participants With Chemotherapy-Induced Peripheral Neuropathy

condition caused by exposure to chemotherapy drugs that may involve numbness/tingling and/or pain in the hands and feet, which can have adverse effects on daily life. Whole body vibration may cause weight

peripheral neuropathy
numbness
cancer
paresthesia
primary cancer
  • 11 views
  • 25 Jan, 2021
  • 2 locations
Ibrutinib and Venetoclax in Treating Patients With Chronic Lymphocytic Leukemia After Ibrutinib Resistance

resistance may work better than discontinuing ibrutinib and switching to other chemotherapy drugs.

chemotherapy drugs
chronic lymphocytic leukemia
cancer
neutrophil count
ibrutinib
  • 0 views
  • 25 Jan, 2021
  • 3 locations
INCMGA00012 (Anti-PD-1 Antibody) With Gemcitabine and Docetaxel in Patients With Advanced Soft Tissue Sarcoma

treatment for your disease. Gemcitabine and docetaxel are chemotherapy drugs that are commonly used to treat soft tissue sarcoma. INCMGA00012 is an experimental drug that boosts the immune system's ability

cancer chemotherapy
cancer
neutrophil count
soft tissue sarcoma
advanced soft tissue sarcoma
  • 0 views
  • 28 Jan, 2021
  • 1 location