Found 164 clinical trials
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Testing the Combination of MLN4924 (Pevonedistat) Carboplatin and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With Immunotherapy
growth of cancer cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as carboplatin and paclitaxel, work in different ways to stop the growth of cancer cells, either by
- 1 views
- 27 Jan, 2021
- 4 locations
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Immunology
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Currently Recruiting
Intrathecal Rituximab With Standard Intrathecal Prophylaxis to Prevent CNS Relapse for CD 20+ Non Hodgkin Lymphoma
The purpose of this research study is to learn if giving rituximab, the study drug, right into the spinal canal along with chemotherapy drugs like methotrexate is possible and safe.
- 1 views
- 23 Jan, 2021
- 1 location
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Accepting pediatric ages
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Accepting Seniors
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10s of participants
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An interventional trial
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For all genders
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Neurology
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Currently Recruiting
Study of Chemoimmunotherapy for High-Risk Neuroblastoma
The purpose of this study is to find out whether an experimental drug called Hu3F8 can be given with the chemotherapy drugs irinotecan and temozolomide and another drug called GM-CSF. The
- 30 views
- 26 Jan, 2021
- 1 location
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Phase 2 trial
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Accepting adults
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10s of participants
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An interventional trial
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For females only
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Currently Recruiting
Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Metastatic Triple-negative Breast Cancer
to give higher doses of chemotherapy drugs and kill more tumor cells.
- 76 views
- 24 Jan, 2021
- 1 location
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Phase 2 trial
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Accepting pediatric ages
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Family Medicine
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Currently Recruiting
Transplantation Using Reduced Intensity Approach for Patients With Sickle Cell Disease From Mismatched Family Donors of Bone Marrow
-matched related donors. Preparation before transplant includes the chemotherapy drugs hydroxyurea, fludarabine, thiotepa, anti-thymocyte globulin, and cyclophosphamide. It also includes radiation.
- 33 views
- 13 Feb, 2021
- 1 location
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Oncology
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Currently Recruiting
A Study of Two Dosing Schedules of Atezolizumab in Combination With Gemcitabine and Cisplatin as First-Line Treatment for Metastatic Bladder Cancer
The purpose of this study is to compare any good and bad effects the study drug atezolizumab has on the cancer when combined with the standard chemotherapy drugs gemcitabine and cisplatin (or GC
- 44 views
- 27 Jan, 2021
- 16 locations
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Oncology
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Currently Recruiting
A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or Leg
The purpose of this study is to find out whether giving the study drug pembrolizumab in combination with the chemotherapy drugs melphalan and dactinomycin, delivered directly to the affected arm
- 0 views
- 05 Feb, 2021
- 7 locations
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Oncology
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Currently Recruiting
Whole Body Vibration for the Improvement of Health and Functioning in Participants With Chemotherapy-Induced Peripheral Neuropathy
condition caused by exposure to chemotherapy drugs that may involve numbness/tingling and/or pain in the hands and feet, which can have adverse effects on daily life. Whole body vibration may cause weight
- 11 views
- 25 Jan, 2021
- 2 locations
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Family Medicine
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Currently Recruiting
Ibrutinib and Venetoclax in Treating Patients With Chronic Lymphocytic Leukemia After Ibrutinib Resistance
resistance may work better than discontinuing ibrutinib and switching to other chemotherapy drugs.
- 0 views
- 25 Jan, 2021
- 3 locations
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Phase 1 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Oncology
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Currently Recruiting
INCMGA00012 (Anti-PD-1 Antibody) With Gemcitabine and Docetaxel in Patients With Advanced Soft Tissue Sarcoma
treatment for your disease. Gemcitabine and docetaxel are chemotherapy drugs that are commonly used to treat soft tissue sarcoma. INCMGA00012 is an experimental drug that boosts the immune system's ability
- 0 views
- 28 Jan, 2021
- 1 location