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Found 167 clinical trials
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma the EQUATE Trial

dexamethasone). Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as lenalidomide, work in different ways to stop the growth of

platelet count
cancer
bortezomib
bone marrow procedure
lenalidomide
  • 0 views
  • 03 Mar, 2021
  • 290 locations
Cediranib Maleate and Olaparib or Standard Chemotherapy in Treating Patients With Recurrent Platinum-Resistant or -Refractory Ovarian Fallopian Tube or Primary Peritoneal Cancer

treated with platinum-based chemotherapy drugs (platinum-refractory). Cediranib maleate and olaparib may stop the growth of tumor cells by blocking enzymes needed for cell growth. Drugs used in

bevacizumab
olaparib
cediranib
undifferentiated carcinoma
platinum-based chemotherapy
  • 1729 views
  • 26 Feb, 2021
  • 212 locations
Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer The PDIGREE Study

monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Chemotherapy drugs, such as

programmed cell death 1 ligand 1
nivolumab
platelet count
nephrectomy
interleukin 2
  • 157 views
  • 01 Mar, 2021
  • 653 locations
De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage HPV-Positive Non-Smoking Associated Oropharyngeal Cancer

cells and shrink tumors. Chemotherapy drugs, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them

ct scan
nivolumab
cavity
hepatitis b virus surface antigen
dysphagia
  • 16 views
  • 03 Mar, 2021
  • 208 locations
Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors

transplant stops the growth of cancer cells by stopping them from dividing or killing them. Giving colony-stimulating factors, such as filgrastim or pegfilgrastim, and certain chemotherapy drugs, helps stem

platelet count
testicular
g-csf
tumor cells
high-dose chemotherapy
  • 803 views
  • 19 Feb, 2021
  • 94 locations
CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy

cells to grow are blocked and the tumor cell may be marked for destruction by the body's immune system. Giving paclitaxel, trastuzumab, and pertuzumab may enable fewer chemotherapy drugs to be given

chronic hepatitis b
lumpectomy
ejection fraction
carcinoma in situ
core needle biopsy
  • 43 views
  • 01 Mar, 2021
  • 478 locations
PHASE III RANDOMISED TRIAL TO EVALUATE FOLFOX WITH OR WITHOUT DOCETAXEL (TFOX) AS 1st LINE CHEMOTHERAPY FOR LOCALLY ADVANCED OR METASTATIC OESOPHAGO-GASTRIC CARCINOMA

advanced stages of gastric or gastro-oesophageal junction adenocarcinoma, the combination of 2 chemotherapy drugs (dual therapy) as compared with monotherapy or no chemotherapy, makes it possible to

  • 11 views
  • 26 Jan, 2021
  • 149 locations
To Reduce the Use of Chemotherapy in Postmenopausal Patients With ER-positive and HER2-positive Breast Cancer (TOUCH)

This is a phase II open-label, multicentre, randomized trial. The study assesses the treatment of postmenopausal patients with hormone receptor positive/HER2 positive early breast cancer with neoadjuvant palbociclib in combination with hormonal therapy and HER2 blockade, versus the treatment with paclitaxel in combination with HER2 blockade.

invasive breast cancer
palbociclib
muga scan
her2/neu-positive breast cancer
core needle biopsy
  • 17 views
  • 30 Jan, 2021
  • 63 locations
Testing the Combination of Two Approved Chemotherapy Drugs and Radiation Prior to Surgery in Localized Pancreatic Cancer

The purpose of this phase 2 research study is to determine whether a combination of chemotherapy drugs plus radiation therapy, given before surgery in resectable pancreactic cancer, can help to

antibiotics
cancer
chemotherapy drug
gemcitabine
paclitaxel
  • 0 views
  • 24 Jan, 2021
  • 1 location
Testing the Combination of MLN4924 (Pevonedistat) Carboplatin and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With Immunotherapy

growth of cancer cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as carboplatin and paclitaxel, work in different ways to stop the growth of cancer cells, either by

pevonedistat
chronic hepatitis b
platelet count
HIV Infection
antiretroviral therapy
  • 1 views
  • 27 Jan, 2021
  • 4 locations