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Found 181 clinical trials
Magnetic Resonance (MR) Guided Dose-Escalated Radiation Therapy (RT) + Chemotherapy in Pancreatic Cancer

This research study is for people who have pancreas cancer for which surgery is not recommended. Potential patients must have already received several months of chemotherapy before they are eligible for this study and there will not have been any detectable spread of their tumor on imaging studies following this …

cancer
ct scan
neutrophil count
gemcitabine
metastasis
  • 7 views
  • 06 Mar, 2021
  • 1 location
A Clinical Study to Evaluated Which Number of Passes of EUS-FNB is Better for Culturing Primary Cells of PDAC

The Aim of this study is to investigate the amount of tissue required for the successful culture of primary cells from human-derived pancreatic ductal adenocarcinoma which obtained by endoscopic ultrasound-guided fine-needle biopsy wet suction technique

  • 0 views
  • 18 Mar, 2021
  • 1 location
Niraparib in Combination With Cabozantinib (XL184) in Patients With Advanced Urothelial Cancer (NICARAGUA)

Cabozantinib is an oral, small-molecule tyrosine kinase inhibitor. Its primary targets are Hepatocyte growth factor receptor protein (MET), vascular endothelial growth factor receptor 1-3 (VEGFR1-3), RET, AXL, FLT3 and KIT. Cabozantinib has been approved by the FDA for clinical treatment of progressive, metastatic medullary thyroid cancer. Recently published trials have …

hysterectomy
programmed cell death protein 1
advanced urothelial carcinoma
kinase inhibitor
oophorectomy
  • 46 views
  • 26 Jan, 2021
  • 12 locations
Randomized Control Trial (RCT) of Transarterial Chemoembolization (TACE) Versus TACE and Oral Drug Therapy in the Treatment of Unresectable Hepatocellular Carcinoma

Background Hepatocellular carcinoma, a malignant tumor of liver is one of the most common cancers worldwide. All India Institute Of Medical Sciences (AIIMS) being a tertiary care hospital receives about two to three cases of Hepatocellular carcinoma (HCC) each day in our Gastroenterology out patient department. Most of these patients …

chemoembolization
cancer
cirrhosis
TACE
unresectable hepatocellular carcinoma
  • 30 views
  • 07 Nov, 2020
  • 1 location
ALL SCTped FORUM - Pharmacogenomic Study (add-on Study)

prescribed chemotherapy drugs. This add-on research aims to prospectively investigate variations in several candidate genes related to all types of chemotherapeutic drugs and TBI used in the main

chemotherapy drug
cancer
lymphoid leukemia
busulfan
remission
  • 13 views
  • 23 Jan, 2021
  • 8 locations
Daunorubicin and Cytarabine With or Without Uproleselan in Treating Older Adult Patients With Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapy

chemotherapy. Drugs used in chemotherapy, such as daunorubicin and cytarabine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by

induction chemotherapy
acute promyelocytic leukemia
leukapheresis
decitabine
tyrosine
  • 25 views
  • 14 Jun, 2021
  • 104 locations
Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) in Stage III-IV or Recurrent Endometrial Cancer

the ability of tumor cells to grow and spread. Paclitaxel and carboplatin are chemotherapy drugs used as part of the usual treatment approach for this type of cancer. This study aims to assess if

adenocarcinoma
replacement therapy
monoclonal antibodies
hysterectomy
recurrent endometrial cancer
  • 71 views
  • 16 Jun, 2021
  • 173 locations
Cediranib Maleate and Olaparib or Standard Chemotherapy in Treating Patients With Recurrent Platinum-Resistant or -Refractory Ovarian Fallopian Tube or Primary Peritoneal Cancer

treated with platinum-based chemotherapy drugs (platinum-refractory). Cediranib maleate and olaparib may stop the growth of tumor cells by blocking enzymes needed for cell growth. Drugs used in

fallopian tube
cediranib
bevacizumab
olaparib
neutrophil count
  • 1729 views
  • 16 Jun, 2021
  • 212 locations
Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma

. Brentuximab vedotin is a monoclonal antibody, brentuximab, linked to a toxic agent called vedotin. Brentuximab attaches to cancer cells in a targeted way and delivers vedotin to kill them. Chemotherapy drugs

monoclonal antibodies
hypothyroidism
human immunodeficiency virus
hysterectomy
corticosteroids
  • 68 views
  • 16 Jun, 2021
  • 499 locations
Testing the Addition of an Anti-cancer Immune Therapy Drug (Nivolumab) to the Usual Chemotherapy Treatment (Cisplatin or Carboplatin With Gemcitabine) for Recurrent or Metastatic Nasopharyngeal Cancer

cancer, and may interfere with the ability of tumor cells to grow and spread. Chemotherapy drugs, such as cisplatin, carboplatin, and gemcitabine, work in different ways to stop the growth of tumor cells

cancer
monoclonal antibodies
hbsag
absolute neutrophil count
carboplatin
  • 0 views
  • 16 Jun, 2021
  • 254 locations