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Found 164 clinical trials
Combination Therapy With Pembrolizumab and sEphB4-HSA in Previously Treated Urothelial Carcinoma

other places in the body or has come back and does not respond to certain chemotherapy drugs. Combinations of biological substances in recombinant EphB4-HSA fusion protein may be able to carry tumor

  • 3 views
  • 22 Jan, 2021
  • 2 locations
Salvage Therapy With Sunitinib Docetaxel and Platinum on Metastatic or Unresectable Non Small Cell Lung Cancer

-small cell lung cancer patients are with anti-tumor activity. The chemotherapy drugs, such as docetaxel and platinum-based compounds, were with evidence that they have direct

serum bilirubin level
measurable disease
cancer chemotherapy
carcinoma
ct scan
  • 2 views
  • 08 Nov, 2020
  • 1 location
Neoadjuvant Therapy Followed by Stereotactic Body Radiotherapy (SBRT) for Locally Advanced Pancreatic Cancer

The purpose of this study is to evaluate a new treatment routine for patients with borderline resectable and unresectable pancreas cancers.

pancreatic neoplasm
measurable disease
folfirinox
gemcitabine
cancer chemotherapy
  • 9 views
  • 08 Nov, 2020
  • 1 location
Magnetic Resonance (MR) Guided Dose-Escalated Radiation Therapy (RT) + Chemotherapy in Pancreatic Cancer

This research study is for people who have pancreas cancer for which surgery is not recommended. Potential patients must have already received several months of chemotherapy before they are eligible for this study and there will not have been any detectable spread of their tumor on imaging studies following this …

cancer
neutrophil count
gemcitabine
ct scan
metastasis
  • 7 views
  • 25 Jan, 2021
  • 1 location
Niraparib in Combination With Cabozantinib (XL184) in Patients With Advanced Urothelial Cancer (NICARAGUA)

Cabozantinib is an oral, small-molecule tyrosine kinase inhibitor. Its primary targets are Hepatocyte growth factor receptor protein (MET), vascular endothelial growth factor receptor 1-3 (VEGFR1-3), RET, AXL, FLT3 and KIT. Cabozantinib has been approved by the FDA for clinical treatment of progressive, metastatic medullary thyroid cancer. Recently published trials have …

measurable disease
metastatic cancer
programmed cell death protein 1
carcinoma
bladder cancer
  • 46 views
  • 26 Jan, 2021
  • 12 locations
Randomized Control Trial (RCT) of Transarterial Chemoembolization (TACE) Versus TACE and Oral Drug Therapy in the Treatment of Unresectable Hepatocellular Carcinoma

Background Hepatocellular carcinoma, a malignant tumor of liver is one of the most common cancers worldwide. All India Institute Of Medical Sciences (AIIMS) being a tertiary care hospital receives about two to three cases of Hepatocellular carcinoma (HCC) each day in our Gastroenterology out patient department. Most of these patients …

cancer
TACE
unresectable hepatocellular carcinoma
chemoembolization
cirrhosis
  • 30 views
  • 07 Nov, 2020
  • 1 location
Daunorubicin and Cytarabine With or Without Uproleselan in Treating Older Adult Patients With Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapy

chemotherapy. Drugs used in chemotherapy, such as daunorubicin and cytarabine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by

daunorubicin
hydroxyurea
acute leukemia
acute promyelocytic leukemia
leukapheresis
  • 25 views
  • 24 Feb, 2021
  • 98 locations
ALL SCTped FORUM - Pharmacogenomic Study (add-on Study)

prescribed chemotherapy drugs. This add-on research aims to prospectively investigate variations in several candidate genes related to all types of chemotherapeutic drugs and TBI used in the main

cancer
lymphoid leukemia
chemotherapy drug
cell transplantation
b-cell acute lymphoblastic leukemia
  • 13 views
  • 23 Jan, 2021
  • 8 locations
Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) in Stage III-IV or Recurrent Endometrial Cancer

the ability of tumor cells to grow and spread. Paclitaxel and carboplatin are chemotherapy drugs used as part of the usual treatment approach for this type of cancer. This study aims to assess if

undifferentiated carcinoma
measurable disease
MRI
monoclonal antibodies
absolute neutrophil count
  • 71 views
  • 24 Feb, 2021
  • 135 locations
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma the EQUATE Trial

dexamethasone). Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as lenalidomide, work in different ways to stop the growth of

measurable disease
bone marrow procedure
plasmacytosis
electrophoresis
lenalidomide
  • 0 views
  • 12 Feb, 2021
  • 290 locations