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Found 180 clinical trials
NHS-IL12 Monotherapy and in Combination With M7824 in Advanced Kaposi Sarcoma

, such as among people living with HIV or those with prior history of transplant. Researchers want to see if 2 non-chemotherapy drugs can help people with KS. NHS-IL12 triggers the immune system to fight

cytotoxic chemotherapy
protease
progressive disease
systemic therapy
doxorubicin
  • 12 views
  • 24 May, 2021
  • 1 location
E7 TCR T Cells for Human Papillomavirus-Associated Cancers

stay in the hospital. Over several days, they will get: Chemotherapy drugs E7 TCR cells Shots or injections to stimulate the cells Participants will be monitored in the

hysterectomy
filgrastim
hepatitis b antigen
white blood cells
hpv vaccine
  • 342 views
  • 24 Jun, 2021
  • 1 location
Venetoclax in Combination With Intensive Induction and Consolidation Chemotherapy in Treatment Na ve AML

This research study is studying the combination of venetoclax and chemotherapy as a possible treatment for acute myelogenous leukemia (AML). The drugs involved in this study are: Venetoclax Daunorubicin Cytarabine

cytarabine
daunorubicin
gilbert's syndrome
tretinoin
hydroxyurea
  • 6 views
  • 27 Mar, 2021
HIPEC in the Treatment of Stage IIc-IV Epithelial Ovarian Cancer After CRS (HIPECOC)

This study evaluate the Hyperthermic Intraperitoneal Chemotherapy(HIPEC) in the treatment of Stage IIc-IV epithelial Ovarian Cancer after primary Cytoreductive Surgery (CRS).Half participants will receive HIPEC twice with one intravenous chemotherapy and 5 cycles of intravenous chemotherapy with carboplatin and paclitaxel after CRS. Half participants will receive 6 cycles of intravenous …

cytoreductive surgery
ovarian epithelial cancer
cancer of the ovary
carboplatin
peritoneal cancer
  • 20 views
  • 24 Jan, 2021
  • 1 location
Toripalimab Combined With CAV / IE Regimen

The aim of this study was to investigate the efficacy and safety of CAV / IE chemotherapy combined with toripalimab in the treatment of patients with advanced or unresectable bone and soft tissue sarcomas who failed in standard treatment.

  • 0 views
  • 30 Mar, 2021
  • 1 location
The Clinical Study of Apatinib Plus S1 for Patients With Advanced Non-squamous Head and Neck Cancer

This is a Single-center, Open-label, Single-arm, Phase exploratory clinical trial evaluating the efficacy and safety of Apatinib plus S1 for patients with advanced (unresectable, locally advanced, recurrent or metastatic) non-squamous head and neck cancer.

neck cancer
platelet count
head and neck cancer
apatinib
measurable disease
  • 10 views
  • 21 Jan, 2021
Phase I Trial HIPEC With Nal-irinotecan

The purpose of this study is to assess the effectiveness and safety of intraperitoneal administration of heated nanoliposomal Irinotecan in cytoreductive surgery (CRS), which is surgery designed to remove as much of the cancer as possible, and heated intraperitoneal chemotherapy (HIPEC) procedures.

  • 0 views
  • 27 Jan, 2021
  • 2 locations
Inotuzumab Ozogamicin and Chemotherapy in Treating Patients With Leukemia or Lymphoma Undergoing Stem Cell Transplantation

The goal of this phase II clinical study is to learn about the safety of inotuzumab ozogamicin when given with fludarabine, with or without bendamustine, melphalan, and rituximab before and after a stem cell transplant. Researchers also want to learn if inotuzumab ozogamicin when given after a stem cell transplant …

b-cell acute lymphoblastic leukemia
filgrastim
antibody therapy
human chorionic gonadotropin
melphalan
  • 2 views
  • 16 May, 2021
  • 1 location
The Value of Sintilimab Consolidation Therapy After Definitive Concurrent Chemoradiotherapy for Locally Advanced Thoracic Esophageal Cancer

Esophageal cancer is a kind of disease with high incidence and mortality. Definitive concurrent chemoradiotherapy is an important treatment for locally advanced esophageal squamous cell carcinoma. To Investigate the value of immunotherapy consolidation in locally advanced esophageal squamous cell carcinoma after completing radical concurrent chemoradiotherapy.

squamous cell carcinoma
chemoradiotherapy
esophagus cancer
esophageal cancer
sintilimab
  • 0 views
  • 25 Jan, 2021
  • 1 location
Trial of Intraperitoneal (IP) Oxaliplatin in Combination With Intravenous FOLFIRI

This is a Phase I dose escalation study to determine how much chemotherapy can be safely administered into the abdomen while experiencing the fewest possible side effects.

folfiri
oxaliplatin
laparoscopy
gilbert's syndrome
serum bilirubin
  • 32 views
  • 25 Jan, 2021
  • 1 location