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Found 179 clinical trials
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A Randomized Phase III Trial of Adjuvant Therapy Comparing Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel with or without Carboplatin for Node-Positive or High-Risk Node-Negative Triple-Negative Invasive Breast Cancer

A Randomized Phase III Trial of Adjuvant Therapy Comparing Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel with or without Carboplatin for Node-Positive or High-Risk Node-Negative Triple-Negative Invasive Breast Cancer

doxorubicin
invasive breast cancer
breast cancer
carboplatin
cyclophosphamide
  • 66 views
  • 03 Dec, 2020
  • 1 location
featured
A Biomarker-Driven Master Protocol for Previously Treated Squamous Cell Lung Cancer (Screening Step) Lung-MAP Study

A Biomarker-Driven Master Protocol for Previously Treated Squamous Cell Lung Cancer (Screening Step) Lung-MAP Study

lung carcinoma
lung cancer
cancer
  • 28 views
  • 23 Nov, 2020
  • 1 location
Combination Chemotherapy With or Without Filgrastim Before Surgery High-Dose Chemotherapy and Radiation Therapy Followed by Isotretinoin With or Without Monoclonal Antibody in Treating Patients With Neuroblastoma

from the side effects of chemotherapy. Combining chemotherapy with peripheral stem cell transplant may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells

isotretinoin
high dose chemotherapy
filgrastim
stem cell transplantation
tumor cells
  • 46 views
  • 07 Nov, 2020
  • 15 locations
Ribociclib in Combination With Everolimus and Dexamethasone in Relapsed ALL

This research study is evaluating a drug called ribociclib (LEE011) given in combination with everolimus and other standard of care chemotherapy drugs as a possible treatment for relapsed or

  • 13 views
  • 27 Jan, 2021
  • 9 locations
Phase I Nab-Paclitaxel Plus Gemcitabine With Proton Therapy for Locally Advanced Pancreatic Cancer (LAPC)

The purpose of this study is to determine the maximum tolerated dose of the chemotherapy drugs nab-paclitaxel and gemcitabine when combined with hypofractionated ablative proton therapy for the

  • 3 views
  • 25 Jan, 2021
  • 3 locations
Short-Term Fasting: Impact on Toxicity

fasting before chemotherapy may reduce the side effects caused by chemotherapy. Drugs used in chemotherapy, such as gemcitabine hydrochloride and cisplatin, work in different ways to stop the growth of

  • 30 views
  • 23 Jan, 2021
  • 1 location
Dose-Dense Chemotherapy Plus Bevacizumab in High Risk Lymph Node Positive Breast Cancer: A Pilot Study

bevacizumab, a drug which is FDA approved for colon cancer but not for breast cancer, in combination with a regimen of approved chemotherapy drugs known as "dose dense chemotherapy." The study will

endocrine therapy
metastasis
hormone therapy
chemotherapy drugs
bevacizumab
  • 10 views
  • 07 Nov, 2020
  • 1 location
Combination Therapy With Pembrolizumab and sEphB4-HSA in Previously Treated Urothelial Carcinoma

other places in the body or has come back and does not respond to certain chemotherapy drugs. Combinations of biological substances in recombinant EphB4-HSA fusion protein may be able to carry tumor

  • 3 views
  • 22 Jan, 2021
  • 2 locations
Pegylated Liposomal Doxorubicin PD-1 in Treating Muscle Invasive Bladder Cancer

, second line chemotherapy drugs can be chosen from doxorubicin, docetaxel, pemetrexed, etc. This non-randomized, prospective study aims to explore the efficacy and safety of PEGylated liposomal

  • 0 views
  • 23 Jan, 2021
  • 1 location
Salvage Therapy With Sunitinib Docetaxel and Platinum on Metastatic or Unresectable Non Small Cell Lung Cancer

-small cell lung cancer patients are with anti-tumor activity. The chemotherapy drugs, such as docetaxel and platinum-based compounds, were with evidence that they have direct

docetaxel
serum bilirubin level
growth factor
solid tumour
stage iv non-small cell lung cancer
  • 2 views
  • 08 Nov, 2020
  • 1 location