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Found 81 clinical trials
Neoadjuvant PD-1 Inhibitor, Anlotinib Combined With Chemotherapy in Resectable Stage IIA-IIIB NSCLC

primary purpose:Observe the pathological complete response rate (PCR) of postoperative tumor tissue resection and evaluate the safety of the treatment process.

measurable disease
sintilimab
renal function
lung carcinoma
Accepts healthy volunteers
  • 0 views
  • 19 Jun, 2022
  • 1 location
Adoptive TKC Transfer Combined With Chemotherapy for Advanced Non-small Cell Lung Cancer (NSCLC)

Innate immune cells are an important part of the body's innate immune system, the first line of defense against infection and cancer. Tumor killer cells (TKC) are mixed cultures of two kinds of innate immune cells, namely natural killer cells (NK cells) and gamma delta T cells (T cells), which …

absolute neutrophil count
measurable disease
blood transfusion
lung cancer
cancer
  • 0 views
  • 13 Aug, 2021
  • 1 location
Donafenib for Recurrent Cervical Cancer

This study is to evaluate the safety and tolerability of Donafenib combined with paclitaxel and platinum ± programmed death 1 monoclonal antibody (PD-1 antibody) in patients with recurrent cervical cancer.

absolute neutrophil count
carcinoma
measurable disease
creatinine clearance rate
metastasis
  • 0 views
  • 19 Apr, 2022
  • 1 location
Immunotherapy for Recurrent Cervical Cancer Refractory to Platinum-based Chemotherapy: Multi-Center Trial

This is a updated trial of NCT04188860 as a multi-center study. For recurrent or persistent advanced cervical cancer patients, the first-line chemotherapy was based on platinum. However, if they were refractory to platinum-based chemotherapy, there were no other more effective medications or treatment. The marketing of anti-PD-1 antibody has provided …

carcinoma
measurable disease
camrelizumab
cancer
treatment regimen
  • 0 views
  • 11 Apr, 2022
  • 1 location
Assessment of Survival and Autonomy With Rituximab Plus Chemotherapy or Rituximab Plus Lenalidomide for Elderly Patients With Relapsed Diffuse Large B-cell Lymphoma

Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma. Annual incidence increases with age and achieves more than 30 per 100 000 patients 65 years old or over. Despite high response rates with conventional regimen as R-CHOP (Rituximab, Cyclophosphamide, Doxorubicin, Vincristine and Prednisone), 30% to 40% …

prednisone
doxorubicin
treatment regimen
gemcitabine
autologous stem cell transplantation
  • 0 views
  • 06 Aug, 2021
  • 1 location
Neoadjuvant Toripalimab and Albumin Paclitaxel /Cisplatin Versus Docetaxel/ Cisplatin/ 5-fluorouracil (TPF) on Pathological Response in Patients With Locally Advanced and Resectable Oral Squamous Cell Carcinoma

To compare the pathological efficacy of neoadjuvant Toripalimab and Albumin paclitaxel /Cisplatin (TTP) with Docetaxel/ Cisplatin/ 5-flurouracil (TPF) for patients with locally advanced resectable oral squamous cell carcinoma (OSCC), and to determine the safety of neoadjuvant TTP. In order to explore a better protocol of neoadjuvant therapy to improve the …

carcinoma
measurable disease
docetaxel
renal function
fluorouracil
  • 0 views
  • 21 Oct, 2022
  • 1 location
Substance Misuse To Psychosis for Stimulants

In Hong Kong, less than 5% of stimulants abusers were reported to misuse these substances via injection. Also, it is well known that patients with co-morbid substance abuse/dependence and psychosis or schizophrenia-related disorders are prone to earlier treatment discontinuation and high oral medication non-adherence, resulting in poorer overall outcomes. With …

substance use disorders
  • 11 views
  • 07 Oct, 2022
  • 1 location
Study of the Therapeutic Response and Survival of Patients With Metastatic Colorectal Cancer (Stage IV) and Treated According to the Guidelines of a Chemosensitivity Test, Oncogramme® (ONCOGRAM) (ONCOGRAM)

Currently, chemotherapies are empirically administered to patients treated for colorectal cancer (CRC). Selection is based on the efficacy of a protocol previously determined on the largest number (consensus treatment), the decision-making process being weighted by patient's intrinsic criteria. However, each patient is unique, due to the inter- and intratumoral heterogeneity …

folfiri regimen
fluorouracil
combinations
systemic chemotherapy
folfirinox
  • 14 views
  • 07 Oct, 2022
  • 7 locations
Personalizing Docetaxel Dosing in Advanced Prostate Cancer (PARTNER)

Patients with advanced prostate cancer are often treated with the chemotherapy drug docetaxel. The manufacturers of this drug suggest using the same dose of drug per m² body surface area for all

  • 3 views
  • 13 Oct, 2022
  • 1 location
Efficacy and Safety of Eribulin in the Treatment of Advanced Breast Cancer

+ metastatic breast cancer, and the efficacy of combined immunotherapy in triple negative metastatic breast cancer. Moreover, as a newly marketed chemotherapy drug in China, the efficacy and safety data of

  • 0 views
  • 26 Jan, 2021
  • 1 location