Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 81 clinical trials
Lurbinectedin + Doxorubicin In Leiomyosarcoma

This research study involves the study drug lurbinectedin in combination with doxorubicin. This research has two parts. The first part is being done to determine the tolerability of lurbinectedin with doxorubicin in people with soft tissue sarcoma. The second part is a randomized study to determine which is more effective …

  • 0 views
  • 23 Mar, 2022
  • 2 locations
Organoid-Guided Chemotherapy for Advanced Pancreatic Cancer

The purpose of this study is to explore whether chemotherapy regimens guided by organoid drug sensitivity test can improve the outcomes of advanced pancreatic cancer. At the same time, this study will evaluate the successful stablishment rate of organoid from biopsy tissue , and explore the concordance between drug sensitivity …

  • 0 views
  • 04 Oct, 2022
  • 1 location
Organoid-Guided Adjuvant Chemotherapy for Pancreatic Cancer

The purpose of this study is to explore whether adjuvant chemotherapy regimens guided by organoid drug sensitivity test can improve the outcomes of pancreatic cancer. At the same time, this study will evaluate the successful establishment rate of organoid from fresh surgical specimens , and explore the concordance between drug …

neutrophil count
adenocarcinoma
pancreatic adenocarcinoma
carcinoma
cancer chemotherapy
  • 0 views
  • 04 Oct, 2022
  • 1 location
Olanzapine Combined With Fosaprepitant, Ondansetron, and Dexamethasone for Preventing Nausea and Vomiting in Patients With Testicular Cancer

This study aims to investigate the efficacy and safety of olanzapine combined with fosaprepitant, ondansetron and dexamethasone compared with placebo combined with fosaprepitant, ondansetron and dexamethasone in the prevention of nausea and vomiting in germ-cell tumors receiving 5-day cisplatin chemotherapy

  • 0 views
  • 26 Mar, 2022
  • 1 location
Cisplatin+Pembrolizumab+RT in Vulvar Cancer

This research is being done to see how well the combination of a standard of care drug, investigational drug, and radiation therapy work against unresectable vulvar squamous cell carcinoma. This research study involves the following: Cisplatin (standard of care drug) Pembrolizumab (investigational drug) Radiation Therapy (standard of care intervention)

absolute neutrophil count
total bilirubin
carcinoma
anticoagulants
primary tumor
  • 0 views
  • 19 Apr, 2022
BMT-08: A Comparative Effectiveness Study of Transdermal Granisetron to Ondansetron

Patients undergoing either an autologous or allogeneic hematopoietic stem cell transplant (HSCT) and receiving preparative chemotherapy experience a considerable amount of chemotherapy-induced nausea and vomiting (CINV). Current strategies at reducing CINV in this patient population are suboptimal due to lack of efficacy and supportive evidence, potential for increased adverse events, …

ondansetron
dexamethasone
butyrophenone
granisetron
nausea
  • 1 views
  • 16 Jun, 2022
  • 1 location
A Phase 2 Study of Mirvetuximab Soravtansine (IMGN853) and Pembrolizumab in Endometrial Cancer (EC)

This research study is studying a drug combination as a possible treatment for endometrial cancer. The drugs involved in this study are: mirvetuximab soravtansine (IMGN853) pembrolizumab

hormone therapy
imgn853
hnpcc
measurable disease
cancer
  • 94 views
  • 24 Mar, 2022
  • 1 location
Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA)

The purpose of this study is to determine if a combination of two drugs ipatasertib and atezolizumab works as a treatment for residual cancer in the breast or lymph nodes and have circulating tumor DNA in the blood. This research study involves the following investigational drugs: Sacituzumab govitecan Atezolizumab

gilbert's syndrome
invasive breast cancer
erbb2
immunostimulant
adjuvant therapy
  • 2 views
  • 04 Jun, 2022
  • 6 locations
Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

This research study involves testing the safety and efficacy of an investigational intervention for patients with triple-negative breast cancer (TNBC) that has spread, or metastasized, to other parts the body and is PD-L1-negative. The names of the study interventions involved in this study are: Sacituzumab govitecan (Trodelvy™;IMMU-132) Pembrolizumab (Keytruda®; MK-3475)

corticosteroids
gilbert's syndrome
invasive breast cancer
stage iv breast cancer
erbb2
  • 1 views
  • 17 Mar, 2022
  • 5 locations
Acetyl-Amantadine as a Biomarker in Patients With Glioblastoma

Glioblastoma multiforme (GBM) is the most common brain tumor in adults. The strikingly poor survival for patients with GBM (average survival 14-16 months following diagnosis) is due in part to limited early detection methods and an absence of effective therapeutic options. The study proposed would establish important evidence for the …

  • 0 views
  • 24 Feb, 2021
  • 1 location