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Found 81 clinical trials
BV-CHEP Chemotherapy for Adult T-cell Leukemia or Lymphoma

cancer cells express a type of marker called CD30. Brentuximab vedotin is an antibody that also has a chemotherapy drug attached to it. Antibodies are proteins that are part of the immune system

leukemia
lymphoma
vincristine
ifosfamide
t-cell lymphoma
  • 122 views
  • 01 Jul, 2022
  • 4 locations
A Study of Camrelizumab Combined With Concurrent Chemoradiation in Patients With Cervical Cancer

In this single-arm study, patient with cervical cancer who had recurrence of the pelvic wall after surgery Abdominal aortic lymph node metastasis will be included to evaluate the efficacy and safety of camrelizumab combined with concurrent chemoradiation and subsequent maintenance therapy

squamous cell carcinoma
adenocarcinoma
metastasis
recurrent cervical cancer
adenosquamous carcinoma
  • 0 views
  • 15 Aug, 2021
  • 1 location
A Randomized Phase II Study of 177 LuPSMA-617 vs Docetaxel in Patients With Metastatic Castration-Resistant Prostate Cancer and PSMA-Positive Disease

177Lu PSMA 617 is a new type of therapy which is designed to deliver high doses of radiation directly to prostate cancer sites in the body. The purpose of this study is to find out whether 177Lu PSMA 617can slow the growth of prostate cancer compared to standard chemotherapy treatment

  • 0 views
  • 23 Oct, 2022
  • 5 locations
Trial of NanoPac Intratumoral Injection in Lung Cancer

This study evaluates the use of NanoPac injected directly into tumors in the lung of people with lung cancer.

endobronchial ultrasonography
absolute neutrophil count
endobronchial ultrasound
lung cancer
kidney function test
  • 0 views
  • 07 Dec, 2021
  • 3 locations
A Phase II Study of Durvalumab Treatment Substudy A: In Patients Who Discontinued Prior Checkpoint Therapy Due to Immune Related Toxicity Substudy B: For Continued Treatment (=/- Tremelimumab) of Patients Previously Enrolled to Completed CCTG Studies

I238A: The purpose of this study is to find out what effects being treated with durvalumab has on cancer. The researchers doing this study also want to evaluate if prednisone (a type of steroid), when given together with durvalumab, can reduce any side effects. I238B: The purpose of this study …

measurable disease
targeted therapy
primary cancer
x-rays
immunostimulants
  • 1 views
  • 21 Oct, 2022
  • 11 locations
Phase Ia/Ib Talazoparib + Tazemetostat for mCRPC

This trial is testing whether molecularly targeted oral medications called talazoparib and tazemetostat can be safely combined for the treatment of prostate cancer, and whether the combination is effective in shrinking or preventing the growth of metastatic prostate cancer. The names of the study drugs involved in this study are: …

  • 0 views
  • 04 Oct, 2022
  • 2 locations
Normothermic Intraperitoneal Chemotherapy - Long Term in Peritoneal Metastases From Colorectal Cancer (NIPEC-OXA)

Feasibility study regarding 20 Patients with peritoneal metastases from colorectal cancer treated with cytoreductive surgery and HIPEC and subsequently with 4 courses of normothermic intraperitoneal chemotherapy - long term (NIPEC-OXA) with oxaliplatin.

  • 0 views
  • 09 Oct, 2021
  • 1 location
A Pilot Study of a Personalized Neoantigen Cancer Vaccine With and Without Low-Dose Cyclophosphamide or Pembrolizumab in Treatment Naïve, Asymptomatic Patients With IGHV Unmutated Chronic Lymphocytic Leukemia.

This research study is studying a novel type of CLL vaccine as a possible treatment for chronic lymphocytic leukemia (CLL) The names of the study interventions involved in this study are: Personalized NeoAntigen Vaccine Poly-ICLC Cyclophosphamide Pembrolizumab

  • 0 views
  • 16 Oct, 2022
  • 1 location
GDC-0084 in Combination With Trastuzumab for Patients With HER2-Positive Breast Cancer Brain Metastases

This research study is studying a drug called GDC-0084 as a possible treatment for HER2-Positive Breast Cancer. The drugs involved in this study are: GDC-0084 Trastuzumab (Herceptin®)

her2/neu-positive breast cancer
trastuzumab
metastasis
erbb2
mammogram
  • 2 views
  • 16 Mar, 2022
A Study to Evaluate Pembrolizumab Plus Lenvatinib in PD-L1 Positive TKI Resistant NSCLC Patients

This study will investigate the efficacy and safety of the combination of pembrolizumab and lenvatinib in PD-L1 positive patients with TKI-resistant EGFR-mutated advanced NSCLC.

measurable disease
pembrolizumab
osimertinib
EGFR
  • 0 views
  • 16 Dec, 2021
  • 1 location