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Found 83 clinical trials
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A Randomized Phase III Trial of Adjuvant Therapy Comparing Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel with or without Carboplatin for Node-Positive or High-Risk Node-Negative Triple-Negative Invasive Breast Cancer

A Randomized Phase III Trial of Adjuvant Therapy Comparing Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel with or without Carboplatin for Node-Positive or High-Risk Node-Negative Triple-Negative Invasive Breast Cancer

doxorubicin
cyclophosphamide
invasive breast cancer
breast cancer
paclitaxel
  • 80 views
  • 03 Dec, 2020
  • 1 location
Acupuncture for Peripheral Neuropathy Induced by Paclitaxel in Early Stage Breast Cancer

The present study aims to evaluate the effectiveness of acupuncture in the treatment of chemotherapy drug paclitaxel induced peripheral neuropathy in patients with early stage breast cancer

breast cancer
peripheral neuropathy
paclitaxel
cancer
acupuncture
  • 0 views
  • 24 Jan, 2021
  • 1 location
Tailored Second Line Treatment by Epidermal Growth Factor Receptor (EGFR) Mutation in Patients With Advanced Lung Adenocarcinoma

survival and progression free survival that indicated better efficacy for non-squamous patients treated with pemetrexed. These data supports that pemetrexed could be a preferable chemotherapy

EGFR
kinase inhibitor
recurrent non-small cell lung cancer
pemetrexed
lung adenocarcinoma
  • 9 views
  • 07 Nov, 2020
  • 1 location
A Phase II Trial of Combination Therapy With Celecoxib and Taxotere for the Treatment of Stage D3 Prostate Cancer

refractory prostate cancer. Celecoxib (Celebrex) is an FDA approved drug to treat arthritis. Taxotere (Docetaxel) is an FDA approved chemotherapy drug to treat certain forms of cancer. Both drugs

adenocarcinoma
testosterone
bicalutamide
flutamide
bilateral orchidectomy
  • 51 views
  • 07 Nov, 2020
  • 1 location
Erlotinib and Docetaxel in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) After Failure of One Chemotherapy Regimen

administrated concomitantly, and therefore, it could improve the benefit of the combination therapy. This study will investigate if the intermittent treatment of a chemotherapy drug, such as

cancer chemotherapy
docetaxel
metastasis
neutrophil count
erlotinib
  • 1 views
  • 07 Nov, 2020
  • 6 locations
Drug Sensitivity Screening for Gastrointestinal Cancer

chemotherapy drug sensitivity test in order to: Compare the ex vivo Maximal Inhibition Index(MI) and Drug Sensitivity Index (DSI) with patient's Overall Response Rate (ORR) Provide

  • 0 views
  • 24 Jan, 2021
  • 1 location
Ribociclib in Combination With Everolimus and Dexamethasone in Relapsed ALL

This research study is evaluating a drug called ribociclib (LEE011) given in combination with everolimus and other standard of care chemotherapy drugs as a possible treatment for relapsed or refractory ALL. The names of the drugs involved in this study are: ribociclib everolimus dexamethasone

  • 13 views
  • 06 Aug, 2021
  • 10 locations
Trastuzumab Deruxtecan in Participants With HER2-mutated Metastatic Non-small Cell Lung Cancer (NSCLC)

progression during/after at least one regimen of prior anticancer therapy (second line or later) that must have contained a platinum-based chemotherapy drug.

cancer chemotherapy
HER2
erbb2
lung carcinoma
liquid biopsy
  • 0 views
  • 18 Jul, 2021
  • 53 locations
T-DM1 and Tucatinib Compared With T-DM1 Alone in Preventing Relapses in People With High Risk HER2-Positive Breast Cancer the CompassHER2 RD Trial

cancer. T-DM1 is a monoclonal antibody, called trastuzumab, linked to a chemotherapy drug, called DM1. Trastuzumab is a form of targeted therapy because it attaches to specific molecules (receptors) on

  • 0 views
  • 22 Aug, 2021
  • 817 locations
A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

problems than traditional anthracycline drugs, a common class of chemotherapy drug. Some acute myeloid leukemia patients have an abnormality in the structure of a gene called FLT3. Genes are pieces of DNA

anthracyclines
methotrexate
cytarabine/daunorubicin
cell transplantation
cancer
  • 5 views
  • 01 Sep, 2021
  • 93 locations