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Found 85 clinical trials
PIPAC for Peritoneal Metastases

Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a novel drug delivery system that allows the direct application of chemotherapeutic agents into the peritoneal cavity. It boosts

  • 0 views
  • 15 Jul, 2021
  • 1 location
APG-1252 in Patients With SCLC or Advanced Solid Tumors

; achieves strong synergy with the chemotherapeutic agents, indicating that APG-1252 may have a broad therapeutic potential for the treatment of human cancer as a single agent and in combination with other

  • 84 views
  • 24 Jan, 2021
  • 1 location
Hydration Based on Thoitaine Aloe Vera and Calendula in the Prevention of Hand-Foot Syndrome in Patients Using Capecitabine

Hand-foot syndrome (HFS) is a very common adverse event of many chemotherapeutic agents, especially capecitabine. The HFS can considerably interfere patient quality of life (QoL). The

  • 0 views
  • 12 Apr, 2021
  • 1 location
5FU/LV Irinotecan Temozolomide and Bevacizumab for MGMT Silenced Microsatellite Stable Metastatic Colorectal Cancer.

active chemotherapeutic agents might overcome resistance to single drugs. Temozolomide has modest but non-negligible activity (about 10%) in chemo-refractory patients with MGMT methylated mCRC

  • 0 views
  • 01 Mar, 2021
  • 1 location
Effect of Intratumoral Injection of Gene Therapy for Locally Advanced Pancreatic Cancer

markers for this disease. For these patients, palliative armamentarium consists of conventional chemotherapeutic agents such as Gemcitabine and, more recently, FOLFIRINOX, which offer marginal survival

folfirinox
gemcitabine
antineoplastic
ductal adenocarcinoma
pdac
  • 27 views
  • 24 Jan, 2021
  • 10 locations
Neo-adjuvant FOLF(IRIN)OX for Resectable Pancreatic Adenocarcinoma

response rates and progression-free survival) and well tolerated. Interestingly, the response rate is increased by using more than two chemotherapeutic agents in advanced pancreatic cancer, justifying the

  • 7 views
  • 22 Jan, 2021
  • 1 location
Efficacy and Safety of Aprepitant in Subjects With Multiple Myeloma During and After High-dose Chemotherapy

chemotherapeutic agents and augments the antiemetic activity of 5-HT3 RAs (e.g. Granisetron, Ondansetron) and corticosteroids (e.g. Dexamethasone). Thus Aprepitant (EMEND®) in addition to

remission
melphalan
dexamethasone
high dose chemotherapy
  • 5 views
  • 07 Nov, 2020
Botulinum Toxin A for the Treatment of Chemotherapy Induced Peripheral Neuropathy

Chemotherapy induced peripheral neuropathy (CIPN) is a common side effect of taxanes and platinum derivative based chemotherapeutic agents, common in breast cancer treatment regimens. It can

nerve conduction studies
antineoplastic drugs
metastatic disease
incobotulinumtoxina
peripheral neuropathy
  • 0 views
  • 25 Jan, 2021
  • 1 location
Standard Chemotherapy vs. Chemotherapy Guided by Cancer Stem Cell Test in Recurrent Glioblastoma

The purpose of this clinical study is to confirm the utility of chemosensitivity tumor testing on cancer stem cells (ChemoID) as a predictor of clinical response in poor prognosis malignant brain tumors such as recurrent glioblastoma (GBM).

neutrophil count
brain tumor
glioblastoma multiforme
cancer
residual tumor
  • 33 views
  • 25 Jan, 2021
  • 15 locations
A Phase II Study of Tegafur/Uracil (UFUR )Plus Thalidomide for the Treatment of Advanced or Metastatic Hepatocellular Carcinoma (HCC)

Primary objective: To evaluate the overall response rate of tegafur/uracil (UFUR®) and thalidomide in the treatment of advanced or metastatic hepatocellular carcinoma. Secondary objectives: 1. To determine the disease stabilization rate; 2. To assess the progression-free survival and overall survival; 3. To establish the safety profile; 4. To evaluate the …

neutrophil count
ct scan
hepatitis
arterial embolization
local therapy
  • 4 views
  • 07 Nov, 2020
  • 1 location