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Found 44 clinical trials
Clinical and Experimental Studies to Improve Radiotherapy Outcome in AIDS Cancer Patients

The researchers plan: - To undertake clinical studies of radiotherapy with or without the administration of the chemotherapeutic agent cisplatin, known to be a radiosensitizer

chemotherapeutic agent
cervical carcinoma
cancer
radiosensitizer
  • 197 views
  • 07 Nov, 2020
  • 3 locations
Adjuvant Therapy With Thalidomide for Chemoembolization in Advanced Hepatocellular Carcinoma

cirrhosis due to toxicity of chemotherapeutic agent to the parenchyma liver. Thalidomide has been reported to have antiangiogenic and antimetastatic effects. The objectives of adjuvant therapy

TACE
chemoembolization
antineoplastic
angiogenesis inhibitor
cirrhosis
  • 1 views
  • 07 Nov, 2020
  • 1 location
Intralesional 5-Fluorouracil (5FU) Topical Imiquimod Treatment for SCC

deliver drug to the tumor. For the proposed phase I clinical trial, the investigators will perform intralesional injections of a well characterized, potent chemotherapeutic agent 5-fluorouracil (5FU) with

imiquimod
antineoplastic
fluorouracil
  • 19 views
  • 26 Jan, 2021
  • 1 location
APG-1387 in Patients With Advanced Solid Tumors or Hematologic Malignancies

chemotherapeutic agent. A total of 35 patients with advanced solid tumors or lymphomas have been treated with APG-1387 in two Phase I dose-escalation studies in Australia and in China. Ten dose levels have been

  • 11 views
  • 28 Jan, 2021
  • 3 locations
Neoadjuvant CCRT With/Without Bevacizumab for Locally Advanced ESCC

that the most important prognostic factor is whether a pathological complete response can be achieved after neoadjuvant CCRT. However, the use of new generation chemotherapeutic agent taxanes and

  • 0 views
  • 23 Jan, 2021
  • 1 location
Study of Thymopentin in Patients After Curative Resection of Small Hepatocellular Carcinoma

The purpose of this study is to evaluate the clinical efficacy of thymopentin on the prevention of the recurrence and metastasis of small HCC after resection.

cancer
metastasis
  • 5 views
  • 07 Nov, 2020
  • 1 location
The Combination Chemotherapy of SIRIOX as First- or Second-Line Chemotherapy for Pancreatic Cancer

Pancreatic cancer represents the most lethal of the common malignancies with a 5-year survival rate of less than 5%. For patients who are eligible for potentially curative resection, despite mortality and morbidity rates after surgery have improved, the recurrence rate is up to 85% within 2 years. FOLFIRINOX (fluoropyrimidine/leucovorin plus …

  • 16 views
  • 17 Apr, 2021
  • 2 locations
A Randomised Trial of Cabazitaxel Docetaxel Mitoxantrone or Satraplatin (CDMS) Plus Surgery for Prostate Cancer Patients Without Metastasis

Current agents administered in therapeutic regimens of prostate cancer employ different mechanisms to eliminate neoplastic cells by inducing substantial apoptosis and causing tumor regression. Treatment with neoadjuvant chemotherapy before radical prostatectomy may better control the tumor before it has the chance to convert into the disease of castration-resistant prostate cancer …

  • 3 views
  • 26 Jan, 2021
  • 2 locations
Cardiovascular Prevention Strategies in Elderly Patients With Cancer (CARTIER Clinical Trial)

The CARTIER study is a randomized, multicenter, open-label clinical trial comparing, in elderly patients with cancer under anti-tumoral treatment, two different cardiotoxicity prevention strategies: primary (intensive cardiovascular monitoring focused on prevention and early diagnosis and treatment of cardiotoxicity based in cardio-onco-hematology teams involved in cancer patient care) vs. secondary (current …

lymphoma
primary cancer
cancer
early detection
breast cancer
  • 7 views
  • 31 Jan, 2021
  • 20 locations
Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy

The overall aim of this trial, which is called STAMPEDE, is to assess novel approaches for the treatment of men with prostate cancer who are starting long-term ADT for the first time, termed hormone-nave prostate cancer. This trial aims to see if we can improve the way in which prostate …

prostate cancer metastatic
endocrine therapy
metastatic prostate cancer
adenocarcinoma
neutrophil count
  • 3777 views
  • 26 Jan, 2021
  • 120 locations