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Found 583 clinical trials
Induction Chemotherapy Plus Chemoradiation as First Line Treatment for Locally Advanced Cervical Cancer

Chemoradiation has been the standard treatment for advanced cervical cancer for a decade, but one third of women still die from a failure to control systemic disease. In a recent multicentre

chemoradiotherapy
paclitaxel
cancer
carboplatin
adenosquamous carcinoma
  • 599 views
  • 09 May, 2021
  • 35 locations
Neoadjuvant Chemoradiotherapy vs. Chemotherapy With Radical Gastrectomy and Adjuvant Chemotherapy for Advanced Gastric Cancer

Patients with histologically confirmed gastric adenocarcinoma with locally advanced gastric cancer are randomized in a 1:1 ratio to receive neoadjuvant chemoradiotherapy with DT45Gy/25f plus

adjuvant chemotherapy
gastric adenocarcinoma
adenocarcinoma
capecitabine
xelox regimen
  • 5 views
  • 22 Jan, 2021
  • 1 location
Study of Docetaxel or Vinorelbine Plus Cisplatin in Neoadjuvant Chemoradiotherapy for Esophageal Cancer

The primary objective is to compare docetaxel plus cisplatin (DP) versus vinorelbine plus cisplatin (NP) in neoadjuvant chemoradiotherapy, in terms of the overall survival and toxicity in

cancer treatment
docetaxel
vinorelbine
blood count
carcinoma
  • 15 views
  • 24 Jan, 2021
  • 1 location
Image Guided IMRT Radiochemotherapy and MRI-based IGABT in Locally Advanced Cervical Cancer

The research group on adaptive image-guided radiotherapy for locally advanced cervical carcinoma completed the protocol for the EMBRACE II study in October 2018. This study will be carried out in the next few years at the University Clinic for Radiotherapy at the Medical University of Vienna and other international partner …

cervical carcinoma
adenocarcinoma
carcinoma
pet/ct scan
mri of pelvis
  • 4 views
  • 09 Apr, 2021
  • 1 location
Study of Durvalumab Versus Placebo in Combination With Definitive Chemoradiation Therapy in Patient With ESCC

This is a Phase III, randomized, double-blind, placebo-controlled, multi-center international study to assess the efficacy and safety of durvalumab administered concurrently with dCRT in patients with locally advanced, unresectable esophageal squamous cell carcinoma (ESCC).

durvalumab
fluorouracil
carcinoma
squamous cell carcinoma
capecitabine
  • 3 views
  • 13 Jan, 2022
  • 91 locations
Study of Chemoradiotherapy in Oesophageal Cancer Including PET Response and Dose Escalation (SCOPE2)

to chemotherapy with standard drugs early on in treatment. All patients will receive 6 weeks of chemotherapy and 5 weeks of chemoradiotherapy. How the study will be conducted:

kidney function test
adenocarcinoma
carboplatin
carcinoma
capecitabine
  • 231 views
  • 27 Jan, 2022
  • 21 locations
Placebo-controlled, Study of Concurrent Chemoradiation Therapy With Pembrolizumab Followed by Pembrolizumab and Olaparib in Newly Diagnosed Treatment-Naïve Limited-Stage Small Cell Lung Cancer (LS-SCLC) (MK 7339-013/KEYLYNK-013)

independent central review (BICR). Hypothesis (H1): Concurrent chemoradiation therapy with pembrolizumab followed by pembrolizumab plus olaparib is superior to concurrent chemoradiation therapy alone

olaparib
carboplatin
prophylactic cranial irradiation
pembrolizumab
etoposide
  • 2 views
  • 19 Jan, 2022
  • 143 locations
Testing the Addition of an Antibody to Standard Chemoradiation Followed by the Antibody for One Year to Standard Chemoradiation Followed by One Year of the Antibody in Patients With Unresectable Stage III Non-Small Cell Lung Cancer

This phase III trial studies how well an antibody (durvalumab) with chemotherapy and radiation therapy (chemoradiation) works in treating patients with stage III non-small cell lung cancer that

hysterectomy
carboplatin
monoclonal antibodies
neutrophil count
mitomycin
  • 141 views
  • 19 Jan, 2022
  • 593 locations
Modality of Adjuvant Radiotherapy and Chemotherapy for Stage Endometrial Cancer

cancer. A multicenter, prospective, randomized controlled study to compare the "sanwich" mode of radiochemotherapy and the "concurrent chemoradiotherapy followed by chemotherapy" mode will be carried out

endometrial carcinoma
hysterectomy
adenocarcinoma
carcinoma
neutrophil count
  • 0 views
  • 24 Jan, 2021
  • 1 location
Study of Pembrolizumab With Concurrent Chemoradiation Therapy Followed by Pembrolizumab With or Without Olaparib in Stage III Non-Small Cell Lung Cancer (NSCLC) (MK-7339-012/KEYLYNK-012)

The purpose of this study is to assess the efficacy and safety of pembrolizumab in combination with concurrent chemoradiation therapy followed by either pembrolizumab with olaparib placebo (Arm

lung carcinoma
stage iii non-small cell lung cancer
metastasis
carboplatin
etoposide
  • 145 views
  • 17 Jan, 2022
  • 201 locations