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Found 798 clinical trials
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Quarterback 2b - Sequential Therapy With Reduced Dose Chemoradiotherapy for HPV Oropharynx Cancer

The purpose of this study is to establish the efficacy and toxicity of low dose chemoradiotherapy after induction chemotherapy in patients with locally advanced HPV+ oropharynx cancer and

  • 0 views
  • 30 Aug, 2021
  • 1 location
None
Induction Chemotherapy Radiochemotherapy Consolidation Chemotherapy in Preoperative Treatment of Rectal Cancer

The use of capecitabine based preoperative chemoradiation and adjuvant chemotherapy is standard treatment of locally advanced rectal cancer. It has reduced local recurrence rate to less than

capecitabine
metastasis
total mesorectal excision
chemoradiotherapy
renal function
  • 1 views
  • 08 Nov, 2020
  • 1 location
None
Combination of Chemoradiation Therapy and Epitope Peptide Vaccine Therapy in Treating Patients With Esophageal Cancer

The purpose of this study is to evaluate the safety and immune response of multiple peptides (URLC10, TTK, KOC1 VEGFR1, and VEGFR2) emulsified with Montanide ISA51 in combination with chemotherapy (CDDP, 5-FU) plus radiation therapy in treating patients with unresectable, advanced or recurrent esophageal cancer.

vaccine therapy
peptide vaccine
ct scan
fluorouracil
measurable disease
  • 11 views
  • 07 Nov, 2020
  • 1 location
None
Concurrent Chemoradiotherapy Containing Paclitaxel&Cisplatin With/Without Tarceva in Locally Advanced Esophageal Cancer

This study is multi-center randomized phase III one to evaluate the difference in local-control and survival rate between patients receiving concurrent chemoradiotherapy combined Tarceva

carcinoma
paclitaxel
esophageal carcinoma
chemoradiotherapy
esophageal cancer
  • 4 views
  • 07 Nov, 2020
  • 1 location
None
TPF Induction With Concomitant Chemoradiation to Treat Patients With Head and Neck Cancer

The purpose of this trial is to compare two different treatments for fit patients with head and neck cancer: All patients are given induction-chemotherapy (docetaxel, cisplatin, 5-FU). Subsequently patients are being randomised into two groups: - The first group receives neo-adjuvant chemotherapy ('high' dose cisplatin) and conventional radiotherapy - The …

immunomodulator
squamous cell carcinoma of head and neck
fluorouracil
measurable disease
chemoradiotherapy
  • 10 views
  • 07 Nov, 2020
  • 1 location
None
Concomitant Immune Check Point Inhibitor With Radiochemotherapy in Head And Neck Cancer

Background: Locally advanced head and neck cancer (HNC) is a challenge as, in spite of initial good control with chemoradiation, the majority of patients fails systemically. In the last 2 years

  • 25 views
  • 26 Apr, 2021
  • 1 location
None
Multi-lead ECG to Effectively Optimize Resynchronization Devices: New CRT Recipients

Cardiac resynchronization therapy (CRT), or atrial-synchronized biventricular (BiV) pacing, is an FDA-approved device therapy option for heart failure (HF) patients with reduced left ventricular

ejection fraction
medical therapy
cardiac resynchronization therapy
  • 0 views
  • 27 May, 2021
  • 2 locations
None
Evaluating Trifluridine/Tipiracil Based Chemoradiation in Locally Advanced Rectal Cancer - The Phase I/II TARC Trial

experimental arm with Trifluridine/tipiracil based chemoradiotherapy (CRT) and a standard - calibration arm (internal control) with capecitabine CRT flanked by translational research in patients with locally

  • 1 views
  • 28 Mar, 2021
  • 12 locations
None
Programmed Death-1 (PD-1) Antibody Combined With Chemoradiotherapy in High-risk Recurrent Nasopharyngeal Carcinoma

This is a a prospective, single-arm phase II clinical trial. The purpose of this study is to evaluate the efficacy and adverse effect of PD-1 antibody with chemotherapy in high-risk recurrent nasopharyngeal carcinoma.

  • 0 views
  • 13 Jun, 2021
  • 1 location
None
A Trial of Neoadjuvant mFOLFOXIRI Versus CRT in the EMVI Positive LARC

FOLFOXIRI as neoadjuvant chemotherapy alone for EMVI+ LARC in contrast to the efficacy of standard Chemoradiotherapy (CRT).

  • 0 views
  • 30 Mar, 2021
  • 1 location