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Found 791 clinical trials
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The Randomised Study of Preoperative Radiotherapy With Consolidating Chemotherapy for Unresectable Rectal Cancer

The addition of Oxaliplatin to conventionally fractionated chemoradiation (FULV or capecitabine) is considered as standard in unresectable rectal cancer by the panel of experts. The

metastasis
oxaliplatin
chemoradiotherapy
capecitabine
  • 1 views
  • 07 Nov, 2020
  • 1 location
None
A Study of Durvalumab as Consolidation Therapy in Non-Small Cell Lung Cancer Patients

with locally advanced, unresectable, non-small cell lung cancer (Stage III), who have not progressed following definitive, platinum-based, chemoradiation therapy.

chemoradiotherapy
durvalumab
lung carcinoma
  • 285 views
  • 18 Oct, 2021
  • 153 locations
None
An International Clinical Program for the Diagnosis and Treatment of Children With Ependymoma

to receive additional HD-MTX. Patients will receive conformal radiotherapy (cRT). For patients who remain with a residual inoperable disease after induction chemotherapy and cRT, an 8 Gy

  • 25 views
  • 21 Oct, 2021
  • 63 locations
None
Re-evaluation of Optimal Re-synchronisation Therapy in Patients With Chronic Heart Failure

The objective of the study is to demonstrate that in patients with chronic heart failure who receive optimal medical treatment for this condition and have indication for Cardiac Resynchronisation Therapy, the implantation of a pacemaker (index group) is not inferior to defibrillator (control group) with respect to all-cause mortality.

cardiac resynchronization therapy
cardiomyopathy
medical therapy
ejection fraction
  • 2 views
  • 20 Oct, 2021
  • 357 locations
None
SomPsyNet - Prevention of Psychosocial Distress Consequences in Somatic Medicine: a Model for Collaborative Care

This study is to evaluate the impact of the "stepped and collaborative care model" (SCCM) on health-related quality of life in somatic hospital patients with psychosocial distress.

  • 0 views
  • 28 Mar, 2021
  • 4 locations
None
Three Field Radical Esophagectomy Versus Two Field Esophagectomy - a Prospective Trial

Surgery is the standard treatment for esophageal (food pipe) cancer. Esophageal cancer is known to spread to the lymph nodes (glands) adjacent to the esophagus. The extent of lymph nodes that need to be removed along with removal of the esophagus is a controversial topic. The basic surgery will remain …

adenocarcinoma
esophagectomy
cancer
lymphadenectomy
esophageal cancer
  • 15 views
  • 07 Nov, 2020
  • 1 location
None
Risk-Adjusted Combination Chemotherapy in Treating Young Patients With Acute Lymphoblastic Leukemia

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. A donor stem cell transplant may replace the patient's immune cells …

combination chemotherapy
daunorubicin
cytarabine
lymphoid leukemia
graft-versus-tumor
  • 0 views
  • 07 Nov, 2020
  • 1 location
None
NSCLC Isotoxic Hypofractionated Chemoradiotherapy

Radiotherapy plays an important role in non-small cell lung cancer (NSCLC), and concurrent chemoradiation is considered to be the standard treatment for locally advanced NSCLC. However, due to

lung carcinoma
chemoradiotherapy
stereotactic body radiation therapy
docetaxel
cancer chemotherapy
  • 3 views
  • 25 Jan, 2021
  • 1 location
None
Perioperative Chemoradiotherapy for Potentially Resectable Gastric Cancer

Rationale: Adjuvant chemoradiation considered as standard of care after curative surgery for adenocarcinoma of stomach and gastroesophageal cancer. Preoperative chemotherapy in the in

curative surgery
carcinoma
gastric adenocarcinoma
adenocarcinoma
cancer
  • 12 views
  • 07 Nov, 2020
  • 1 location
None
Efficacy and Safety of Neo-CRT Followed Surgery Compared With Definitive CRT in Patients With Initial Unresectable ESO

Definitive chemoradiotherapy(CRT) has been regarded as a standard of care for patients with unresectable locally advanced esophageal cancer. Patients who are sensitive to CRT can achieve

  • 1 views
  • 23 Jan, 2021
  • 1 location