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Found 756 clinical trials
Re-evaluation of Optimal Re-synchronisation Therapy in Patients With Chronic Heart Failure - An Investigator-initiated, Event-driven, Prospective, Parallel-group, Randomised, Open, Blinded Outcome Assessment (PROBE), Multi-centre Trial Without Investigational Medical Products (Proof of Strategy Trial) (RESET-CRT)

The objective of the study is to demonstrate that in patients with chronic heart failure who receive optimal medical treatment for this condition and have indication for Cardiac Resynchronisation Therapy, the implantation of a pacemaker (index group) is not inferior to defibrillator (control group) with respect to all-cause mortality.

cardiomyopathy
medical therapy
ejection fraction
cardiac resynchronization therapy
  • 2 views
  • 25 Oct, 2022
  • 173 locations
Lead EvaluAtion for Defibrillation and Reliability (LEADR)

The study is designed to assess the safety and efficacy of the Next Generation ICD lead.

  • 7 views
  • 23 Oct, 2022
  • 47 locations
SomPsyNet - Prevention of Psychosocial Distress Consequences in Somatic Medicine: a Model for Collaborative Care (SomPsyNet)

This study is to evaluate the impact of the "stepped and collaborative care model" (SCCM) on health-related quality of life in somatic hospital patients with psychosocial distress.

  • 0 views
  • 26 Apr, 2022
  • 4 locations
NSCLC Isotoxic Hypofractionated Chemoradiotherapy (IHRC)

Radiotherapy plays an important role in non-small cell lung cancer (NSCLC), and concurrent chemoradiation is considered to be the standard treatment for locally advanced NSCLC. However, due to

lung carcinoma
chemoradiotherapy
stereotactic body radiation therapy
cancer chemotherapy
docetaxel
  • 3 views
  • 24 May, 2022
  • 1 location
Neo-NTP-CRT for Locally Advanced ESCC

The investigators hypothesize that nivolumab combined with neoadjuvant chemoradiotherapy (CRT) is safe and effective in patients with locally advanced esophageal squamous cell carcinoma (LAESCC

  • 0 views
  • 29 Nov, 2021
  • 1 location
Surgery or Chemoradiotherapy for Cervical Esophageal Cancer

To compare surgery with definitive chemoradiotherapy for patients with resectable cervical esophageal squamous cell carcinoma.

  • 0 views
  • 05 May, 2022
  • 1 location
ICCRT vs. CRT for Locally Advanced Nasopharyngeal Carcinoma

This trial is a multi-center phase III clinical trial. The purpose of this trial is to explore whether concurrent chemoradiotherapy is not inferior to induction chemotherapy combined with

  • 0 views
  • 07 Oct, 2021
  • 1 location
Mechanistic Clinical Trial of Advanced Imaging for CRT

This is a mechanistic clinical trial with randomization to guidance for the CRT procedure using cardiac magnetic resonance (CMR) and computed tomography angiography (CTA) versus a standard

MRI
angiography
  • 7 views
  • 26 Feb, 2022
  • 1 location
Atovaquone With Radical ChemorADIotherapy in Locally Advanced NSCLC (ARCADIAN)

combination with concurrent CRT in NSCLC. Twenty evaluable participants will be recruited at three centres.

  • 0 views
  • 04 Oct, 2022
  • 3 locations
Effects of CRT Optimization as Assessed by Cardiac MR

Cardiac resynchronization therapy (CRT), or atrial-synchronized biventricular (BiV) pacing, is an FDA-approved device therapy option for heart failure (HF) patients with reduced left ventricular

  • 0 views
  • 04 Oct, 2021
  • 2 locations