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Found 85 clinical trials
Simultaneous Integrated Boost for Mediastinal Lymph Node Recurrence After Radical Surgery of Esophageal Cancer

, the optimal dose remains unknown. In addition, no prospective trials have been conducted to investigate the efficacy and toxicities of salvage chemo-radiotherapy by using simultaneous integrated boost

esophagectomy
carcinoma
esophagus cancer
esophageal cancer
capecitabine
  • 3 views
  • 22 Jan, 2021
  • 1 location
Assessment of Gemcitabine as Chemoradiotherapy in Patients With Locally Advanced Carcinoma of Cervix and Renal Disease

consists in concomitant chemo-radiotherapy based on cisplatin (QT-RT), followed by brachytherapy, with an absolute benefit of 10%. However, the use of cisplatin in patients with renal disease may be

carcinoma
cervical carcinoma
gemcitabine
diabetes
chemoradiotherapy
  • 31 views
  • 24 Jan, 2021
  • 1 location
Gluteal Turnover Flap for Closure of the Perineal Wound After Abdominoperineal Resection for Rectal Cancer

Background About 700 patients per year undergo an abdominoperineal resection (APR) for distal rectal cancer (Dutch Colorectal Audit 2016).Neoadjuvant (chemo

cancer
scar
wound care
abdominoperineal resection
  • 0 views
  • 23 Jan, 2021
  • 1 location
Interleukin-11 Can Prevent and Treat of Radioactive Oral Mucitis

Radiation induced oral mucositis which may result in reduced quality of life is commonly seen during radiotherapy, especially combined with chemotherapy. This study is a prospective, multicenter, and exploratory study. The aim of this study is to explore predictive factors of acute radiotherapy induced oral mucositis in nasopharyngeal carcinoma patients …

mucositis
cancer
carcinoma
nasopharyngeal carcinoma
chemotherapy regimen
  • 14 views
  • 25 Jan, 2021
  • 1 location
Patients With Rectal Cancer: a "Wait-and-see" Approach

Patients with histologically proven adenocarcinoma of the rectum will receive pelvic radiotherapy to a dose of 45Gy in 25 fractions with a tumor boost to a dose of 9Gy in 5 fractions (thus total of 54Gy/30Fx to the primary tumor), combined with radio sensitizing chemotherapy. Patients will then be closely …

neutrophil count
metastasis
adenocarcinoma
  • 8 views
  • 12 Mar, 2021
  • 3 locations
Rituximab Plus MG4101 Indolent CD20-positive Non-Hodgkin Lymphoma (NHL)

Phase II study of rituximab plus MG4101 in patients with relapsed or refractory indolent CD20-positive non-Hodgkin lymphoma (NHL) Investigator-Initiated Trials

  • 3 views
  • 24 Mar, 2021
Nivolumab Plus Chemoradiotherapy in Patients With Muscle-invasive Bladder Cancer (MIBC) Not Undergoing Cystectomy

The purpose of this study is to investigate the effect synchronous use of nivolumab in addition to chemoradiotherapy in patients withnon-metastatic MIBC who are not candidates for radical cystectomy

bladder tumor
invasive bladder cancer
carcinoma
nivolumab
bladder cancer
  • 9 views
  • 26 Jan, 2021
  • 1 location
Intrafractional Vaginal Dilation in Anal Cancer Patients Undergoing Pelvic Radiotherapy

A commercially available vaginal dilator set will be used as measuring device. The grading of vaginal stenosis will be determined as difference of the diameter of vaginal dilator to the baseline. A reduction of the diameter of <20% is defined as vaginal stenosis Grade 1, a reduction of 20-35% as …

  • 0 views
  • 30 Jun, 2021
  • 1 location
Chemoradiotherapy for Advanced Esophageal Cancer

This study aims to show that the addition of carboplatin and paclitaxel chemotherapy to a palliative course of external beam radiation treatment improves both dysphagia relief and patient quality of life in patients with unresectable esophageal cancer.

dysphagia
carcinoma
neutrophil count
platelet count
esophagus cancer
  • 0 views
  • 01 Jul, 2021
  • 1 location
A Study of CS1001 in Subjects With Relapsed or Refractory Extranodal Natural Killer/ T Cell Lymphoma

This is a multicenter, single-arm, phase II study to evaluate the efficacy and safety of CS1001 monotherapy for Relapsed or Refractory Extranodal Natural Killer/ T Cell Lymphoma (NKTL)

  • 3 views
  • 27 Jan, 2021
  • 2 locations