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Found 85 clinical trials
Safety and Antiemetic Efficacy of Akynzeo Plus Dexamethasone During Radiotherapy and Concomitant Weekly Cisplatin

patients receiving concomitant chemo-radiotherapy with weekly cisplatin for at least five weeks.

absolute neutrophil count
akynzeo
emetic
netupitant
antiemetics
  • 7 views
  • 24 Jan, 2021
  • 1 location
Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Oropharyngeal Cancer.

definitive treatment. Current treatment of oropharyngeal cancer are chemo-radiotherapy. There is significant lifelong side effects associated with this approach related to tissue effects of radiotherapy. The

carcinoma
docetaxel
oropharyngeal cancer
human papillomavirus
metastasis
  • 0 views
  • 23 Jan, 2021
Total Neoadjuvant Treatment Without Surgery For Locally Advanced Rectal Cancer

NO-CUT is a one-stage phase II trial seeking to establish whether an oxaliplatin-based chemotherapy preceding standard neo-adjuvant fluoropyrimidines-based chemo radiotherapy, can safely spare

platelet count
adenocarcinoma
xelox regimen
adjuvant therapy
metastasis
  • 1 views
  • 25 Jan, 2021
  • 1 location
TSR-042 as Maintenance Therapy for Patients With High-risk Locally Advanced Cervical Cancer After Chemo-radiation (ATOMICC)

Patients with locally advanced cervical cancer (LACC) despite definitive chemo-radiotherapy, has a poor progression-free survival (PFS) and overall survival (OS). The hypothesis is that the use

carcinoma
ct scan
adenosquamous carcinoma
anticoagulants
adenocarcinoma
  • 34 views
  • 16 Sep, 2021
  • 32 locations
Dose De-escalation and Sentinel Lymph Node Mapping Driven Radiotherapy of Contralateral Neck in cN1-2 HNSCC

treated by primary (chemo)radiotherapy. The elective node irradiation on the contralateral side is not always mandatory and the dose may be too high. In this study, we evaluate two strategies: the

concurrent chemotherapy
cavities
pet-ct scan
primary tumor
chemotherapy regimen
  • 0 views
  • 31 Jul, 2021
  • 4 locations
Watch and Wait as Treatment for Patients With Rectal Cancer

A national cohort study with all patients scheduled for neoadjuvant treatment with (chemo)radiotherapy or short course radiotherapy with delayed surgery 6-8 weeks) for rectal cancer staged as

cancer
rectal carcinoma
pelvic mri
endoscopy
  • 31 views
  • 24 Jul, 2021
  • 2 locations
Avelumab With Chemoradiation in Locally Advanced Rectal Cancer

This trial is investigating the inclusion of avelumab post long-course chemo-radiotherapy in patients with resectable locally advanced rectal cancer. It is hypothesised that this may enhance the

total mesorectal excision
pelvic mri
capecitabine
chemo-radiotherapy
adenocarcinoma
  • 3 views
  • 25 Jan, 2021
  • 1 location
Short-Course Chemoradiotherapy Followed by Chemotherapy for the Treatment of Resectable Gastric Adenocarcinoma

cells and shrink tumors. Giving short-course chemo-radiotherapy before chemotherapy and surgery may help to control the disease.

capecitabine
adenocarcinoma
tumor cells
chemoradiotherapy
gastric cancer
  • 0 views
  • 24 Jan, 2021
Proton Radiation for Unresectable Borderline Resectable or Medically Inoperable Carcinoma of the Pancreas

preoperative chemo-radiotherapy fair somewhat better - although many of these patients are not converted to resectability. It may be argued that intensification of local and regional therapy might 1.) Increase

platelet count
carcinoma
capecitabine
obstruction
adenocarcinoma
  • 25 views
  • 23 Jan, 2021
  • 1 location
Simultaneous Integrated Boost for Mediastinal Lymph Node Recurrence After Radical Surgery of Esophageal Cancer

, the optimal dose remains unknown. In addition, no prospective trials have been conducted to investigate the efficacy and toxicities of salvage chemo-radiotherapy by using simultaneous integrated boost

cancer
esophagectomy
carcinoma
capecitabine
chemo-radiotherapy
  • 3 views
  • 22 Jan, 2021
  • 1 location