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Found 85 clinical trials
Toripalimab Plus Concurrent Chemo-radiotherapy for Unresectable Locally Recurrent Nasopharyngeal Carcinoma

Through multicenter, open-label, randomised clinical trials, we intend to demonstrate that concurrent and adjuvant PD-1 treatment added to concurrent chemo-radiotherapy could further decrease

creatinine clearance rate
carcinoma
measurable disease
recurrent nasopharyngeal carcinoma
administration intravenous
  • 0 views
  • 25 Jan, 2021
  • 6 locations
Bladder Fiducial Markers and Multiparametric-MRI (Mp-MRI) to Optimize Bladder Chemo-radiotherapy

The purpose of this study is to examine the usefulness of implanting small 24-K gold fiducial markers around a bladder tumor site, so that a Radiation Oncologist can identify the original tumor location at the time of radiation treatment. Other goals of the study include assessing whether a new MRI …

renal function
carcinoma of the bladder
renal function test
carcinoma
bladder carcinoma
  • 0 views
  • 31 Aug, 2021
  • 3 locations
Concurrent and Adjuvant PD1 Treatment Combined With Chemo-radiotherapy for High-risk Nasopharyngeal Carcinoma

Through multicenter, open-label, randomised clinical trials, we intend to demonstrate that concurrent and adjuvant PD-1 treatment added to chemo-radiotherapy could further decrease the rate of

creatinine clearance rate
camrelizumab
gemcitabine
epstein-barr virus deoxyribonucleic acid
carcinoma
  • 0 views
  • 26 Jan, 2021
  • 6 locations
Atezolizumab After Chemo-radiotherapy for MIBC Patients Not Eligible for Radical Cystectomy

Patients older than 18 years, with muscle-invasive bladder cancer unfit for radical cystectomy because of age, comorbidities, and/or patient's refusal. This study is designed as a multicentre, single-arm phase II study.

invasive bladder cancer
atezolizumab
bladder tumor
metastasis
cancer
  • 0 views
  • 22 Jun, 2021
  • 14 locations
Definitive Chemo-Radiotherapy for Regionally Advanced Head and Neck Cancer With or Without Up-front Neck Dissection

neck dissection (ND) added to (chemo)radiotherapy ((C)RT) in terms of oncological outcome and survival. Second, with modern RT techniques, a tailored treatment followed after an up-front neck

ct scan
carcinoma
metastasis
cancer
neck dissection
  • 15 views
  • 10 May, 2021
  • 3 locations
Standard Dose Versus High Dose of Radiotherapy in Rectal Preservation With Chemo-radiotherapy in Rectal Cancer Patients

In recent years, an increasing number of retrospective and prospective observational studies have indicated that a subset of rectal cancer patients may avoid surgery if they can achieve a complete response to chemoradiotherapy. Prospective trials, including the previous Danish Watchful Waiting trials (NCT00952926, NCT02438839) in early rectal cancer have demonstrated …

chemoradiotherapy
chemo-radiotherapy
adenocarcinoma of rectum
adenocarcinoma
proctectomy
  • 2 views
  • 30 May, 2021
  • 7 locations
Liver Transplant Combined With Neoadjuvant Chemo-radiotherapy in the Treatment of Unresectable Hilar Cholangiocarcinoma. A Prospective Multicenter Study.

A prospective multicentre pilot study which includes patients 70 years-old diagnosed of unresectable hilar cholangiocarcinoma (hCCA) 3cm in radial diameter, without evidence of lymph node or distant metastases. Liver transplantation preceded by neoadjuvant radio-chemotherapy will be performed in this selected group. The primary endpoint will be overall survival at 1, …

  • 0 views
  • 23 Aug, 2021
  • 1 location
Can the Rectum be Saved by Watchful Waiting or TransAnal Surgery Following (Chemo)Radiotherapy Versus Total Mesorectal Excision for Early REctal Cancer?

Colorectal cancer is the third most common tumour in the UK, Netherlands and Denmark with 41000, 14000 and 4000 new cases per year respectively. Standard primary radical Total Mesorectal Excision (TME) surgery is an oncologically effective treatment for early stage rectal cancer. However, resection of a low rectal tumour requires …

rectal carcinoma
chemoradiotherapy
neutrophil count
transrectal ultrasound
cancer
  • 6 views
  • 22 Jan, 2021
  • 3 locations
Accelerated Hypofractionated vs. Conventionally Fractionated Concurrent CRT for LS-SCLC

concurrent chemo-radiotherapy for limited-stage small cell lung cancer.

limited stage small cell lung cancer
cancer chemotherapy
carboplatin
  • 29 views
  • 08 May, 2021
  • 1 location
Functional Lung Avoidance SPECT-guided Radiation Therapy of Lung Cancer

Study aims to determine if functional lung avoidance based on perfusion single photon emission (SPECT)/CT scan, improves toxicity outcomes for patients with advanced lung cancer undergoing chemo

  • 0 views
  • 29 Jan, 2021
  • 2 locations