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Found 85 clinical trials
Prebiotics and Probiotics During Definitive Treatment With Chemotherapy-radiotherapy SCC of the Anal Canal (BISQUIT)

Phase II randomized study of the use of pre-and probiotics during the definitive treatment of chemotherapy-radiotherapy (Ch-RT) for patients with localized anal canal squamous cell cancer (ACSCC) with the objective of increasing the effectiveness of conventional treatment based on the assumptions of that there is a need for research that …

  • 0 views
  • 29 Jan, 2021
  • 1 location
Atezolizumab After Concurrent Chemo-radiotherapy Versus Chemo-radiotherapy Alone in Limited Disease Small-cell Lung Cancer

Some patients with limited disease small-cell lung cancer (LD SCLC) are cured after chemo-radiotherapy, but the majority relapse and die from their cancer. Better therapy is needed

cancer chemotherapy
atezolizumab
neutrophil count
  • 60 views
  • 27 Jan, 2021
  • 53 locations
A Randomized Phase III Study of Adjuvant Chemotherapy With or Without Chemo-radiotherapy in Patients With Local Advanced Gastric Cancer After D2 Resection.

The purpose of this study is to explore the role of adjuvant chemo-radiotherapy in patients with local advanced gastric cancer.

cancer chemotherapy
adjuvant chemotherapy
immunostimulants
oxaliplatin
platelet count
  • 5 views
  • 21 Jan, 2021
  • 1 location
Predicting Neoadjuvant Therapy Response of Rectal Cancer With MRI

The purpose of this study is to investigate if MRI scans performed after neoadjuvant radiotherapy can predict the therapeutic response of rectal cancer following preoperative chemo-radiotherapy

cancer
rectal carcinoma
chemoradiotherapy
chemo-radiotherapy
  • 0 views
  • 23 Jan, 2021
  • 11 locations
Preoperative FOLFOX Versus Postoperative Risk-adapted Chemotherapy in Patients With Locally Advanced Rectal Cancer

This is a multicenter, prospective, randomized, stratified, controlled, open-label study comparing preoperative FOLFOX versus postoperative risk-adapted chemotherapy in patients with locally advanced rectal cancer and low risk for local failure

  • 0 views
  • 26 Jan, 2021
  • 1 location
Prospective Randomized Clinical Trial on Oral and Intravenous Antibiotic Prophylaxis in Colorectal Surgery.

Elective colon surgery is considered a clean-contaminated procedure, with a Surgical Site Infection (SSI) rate not inferior to 10%. For many years the role of Mechanical Bowel Preparation (MBP) has been universally recognized as an effective measure to reduce colonic bacterial load and consequently SSI rate, mostly in European Countries. …

wound infection
antibiotic therapy
colon surgery
sigmoidectomy
anesthesia
  • 0 views
  • 10 May, 2021
  • 1 location
Toripalimab Plus Concurrent Chemo-radiotherapy for Unresectable Locally Recurrent Nasopharyngeal Carcinoma

Through multicenter, open-label, randomised clinical trials, we intend to demonstrate that concurrent and adjuvant PD-1 treatment added to concurrent chemo-radiotherapy could further decrease

intensity-modulated radiation therapy
karnofsky performance status
recurrent nasopharyngeal carcinoma
toripalimab
creatinine clearance rate
  • 0 views
  • 25 Jan, 2021
  • 6 locations
Bladder Fiducial Markers and Multiparametric-MRI (Mp-MRI) to Optimize Bladder Chemo-radiotherapy

The purpose of this study is to examine the usefulness of implanting small 24-K gold fiducial markers around a bladder tumor site, so that a Radiation Oncologist can identify the original tumor location at the time of radiation treatment. Other goals of the study include assessing whether a new MRI …

chemo-radiotherapy
bladder cancer
bladder tumor
TURB
primary cancer
  • 0 views
  • 31 Aug, 2021
  • 3 locations
Concurrent and Adjuvant PD1 Treatment Combined With Chemo-radiotherapy for High-risk Nasopharyngeal Carcinoma

Through multicenter, open-label, randomised clinical trials, we intend to demonstrate that concurrent and adjuvant PD-1 treatment added to chemo-radiotherapy could further decrease the rate of

karnofsky performance status
induction chemotherapy
ebv dna
epstein-barr virus deoxyribonucleic acid
creatinine clearance rate
  • 0 views
  • 26 Jan, 2021
  • 6 locations
Atezolizumab After Chemo-radiotherapy for MIBC Patients Not Eligible for Radical Cystectomy

Patients older than 18 years, with muscle-invasive bladder cancer unfit for radical cystectomy because of age, comorbidities, and/or patient's refusal. This study is designed as a multicentre, single-arm phase II study.

invasive bladder cancer
bladder cancer
bladder tumor
white blood cell count
transurethral bladder excision
  • 0 views
  • 22 Jun, 2021
  • 14 locations