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Found 10 clinical trials
Immunogenicity and Safety of Quadrivalent HPV Vaccine in Healthy Chinese Female Subjects Aged 9 to 19 Years

This phase 3 study will evaluate the immunogenicity and safety of Quadrivalent HPV recombinant vaccine in Chinese females aged 9 to 26 years

lab tests
hpv vaccine
Accepts healthy volunteers
recombinant vaccine
  • 0 views
  • 10 Mar, 2022
  • 1 location
Evaluate the Efficacy, Immunogenicity and Safety of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females

This study is designed to evaluate the vaccine efficacy, immunogenicity and safety of the 9-valent Human Papillomavirus (Types 6, 11, 16, 18,31,33,45,52 and 58) Recombinant Vaccine (Hansenula Polymorpha) in Chinese Female Subjects Aged 20-45 Years .

cancer
intrauterine device (iud)
primary cancer
cancer of the cervix
human papillomavirus
  • 85 views
  • 13 Mar, 2022
  • 1 location
Immunobridging Study of 9-valent Human Papillomavirus Recombinant Vaccine in Chinese Females Aged 9 to 19 Years

This phase 3 study will evaluate the immunogenicity and safety of 9-valent HPV recombinant vaccine in Chinese females aged 9 to 45 years

recombinant vaccine
human papillomavirus
human papilloma virus vaccine
lab tests
hpv vaccine
  • 2 views
  • 07 Mar, 2022
  • 1 location
Pembrolizumab for the Treatment of Cervical Intraepithelial Neoplasia

This phase II trial studies the effect of pembrolizumab on cervical intraepithelial neoplasia. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.

loop electrosurgical excision procedure
cancer
carcinoma
  • 21 views
  • 23 Mar, 2022
  • 1 location
HPV DNA Vaccine Via Electroporation for HPV16 Positive Cervical Neoplasia

The primary goal of this phase I open label study is to determine the safety and tolerability of pNGVL4aCRTE6E7L2 DNA vaccine, as administered by intramuscular (IM) injection with TriGrid™ electroporation to both HIV- or HIV+ adult female subjects (≥ 19 years), with biopsy confirmed cervical intraepithelial (CIN) II or III …

hpv types
colposcopy
total bilirubin
human papillomavirus
cervical intraepithelial neoplasia grade 2
  • 0 views
  • 29 Apr, 2022
  • 2 locations
Cervical Cancer Screening With Human Papillomavirus Testing (ESTAMPA)

HPV testing for primary cervical cancer screening of women over 30 years of age is likely to become the standard of care in the near future in many areas of the world. Its high sensitivity can significantly improve the effectiveness of screening programs and its prolonged negative predictive value can …

cancer screening
cervical cancer screening
cancer
human papillomavirus
hpv test
  • 116 views
  • 22 Apr, 2022
  • 4 locations
Therapeutic Abstention and Surveillance of Intra-epithelial Histological Lesions of High Grade Cervical CIN2 (Cervical Intraepithelial Neoplasia Grade 2). SUIVICIN (SUIVICIN)

This study proposes to describe and evaluate the rate of spontaneous regression of CIN2 at 2 year of follow up in women between 18 and 39 year old. This follow-up is proposed as an alternative to the treatment of reference (conization) with a possible extension to 4 years

intraepithelial neoplasia
cervical intraepithelial neoplasia
colposcopy
cervical intraepithelial neoplasia grade 2
  • 0 views
  • 18 Apr, 2022
  • 1 location
Predicting Response In Cervical Intraepithelial Neoplasia to Topical Imiquimod Treatment (PRedICT-TOPIC)

Imiquimod is a good non-invasive treatment option for women with cervical high-grade squamous intraepithelial neoplasia (cHSIL), especially those with a possible (future) pregnancy wish. Complete response to imiquimod occurs in 55-73% of patients, however side-effects of imiquimod are common and can be extensive. Therefore, biomarkers which can predict response to …

large loop excision of transformation zone
cin 3
colposcopy
imiquimod
  • 0 views
  • 11 Jul, 2022
  • 1 location
Screening Women With Prior HPV for Anal Neoplasia (SWAN)

The goal of this single arm trial is to prospectively evaluate screening methods for anal cancer precursors in HIV uninfected women with a history of lower genital tract neoplasias and cancers.

  • 0 views
  • 08 Jul, 2022
  • 1 location
Conservative Management of HSIL in Patients With Future Pregnancy Aspiration

Conservative management of high-grade squamous intraepithelial lesions (HSILs) seems safe and justified in young women (<30 years), but evidence is insufficient on whether it is also advisable for older women. This study will be conducted to analyze spontaneous HSIL regression rates in women of reproductive age and establish whether conservative …

  • 0 views
  • 16 Mar, 2021
  • 1 location