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Found 93 clinical trials
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A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Study Of The Efficacy And Safety Of tofacitinib In Subjects With Active Ankylosing Spondylitis (AS).

A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Study Of The Efficacy And Safety Of tofacitinib In Subjects With Active Ankylosing Spondylitis (AS).  

  • 171 views
  • 23 Nov, 2020
  • 1 location
featured
A Phase 3, Multicenter, Randomized, Double Blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Subcutaneous Investigational Product in Patients With Systemic Lupus Erythematosus (SLE)

A Phase 3, Multicenter, Randomized, Double Blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Subcutaneous Investigational Product in Patients With Systemic Lupus Erythematosus (SLE)

  • 674 views
  • 08 Nov, 2020
  • 1 location
Development Field Testing and Evaluation of the Efficacy of a Hand-held Portable and Affordable Thermo-coagulator to Prevent Cervical Cancer in Low- and Middle-income Countries

This project develops, tests and produces a lightweight, cordless, battery driven and rechargeable hand-held device for treating cervical precancer (Liger Thermal Coagulator). The study evaluates its effectiveness compared to the current standard treatment (cryocautery) when used as part of a screen and treat programme using Visual Inspection with Acetic acid …

loop electrosurgical excision
cancer
cancer screening
cervical cancer screening
  • 2 views
  • 23 Jan, 2021
  • 1 location
Safety and Feasibility of TA-CIN Vaccine in HPV16 Associated Cervical Cancer

This study will be looking at what dose of the TA-CIN vaccine is safe and effective in patients with a history of HPV16-associated cervical cancer.

  • 17 views
  • 09 Mar, 2021
  • 2 locations
NAC in Preventing CIN in CRF Patients Who Need Enhanced CT Scan in ED

The purpose of this study is to evaluate the effect of NAC or sodium bicarbonate in preventing the aggravation of renal function in chronic renal failure when enhanced computed tomography scan is checked in emergency room.

renal function study
renal failure
  • 6 views
  • 07 Nov, 2020
  • 2 locations
A Study of CIN-107 in Adults With Treatment-Resistant Hypertension (rHTN)

This is a randomized, double-blind, placebo-controlled, dose-ranging Phase 2 study to evaluate the efficacy and safety of CIN-107 as compared to placebo after 12 weeks of treatment in patients

antihypertensive drugs
medication regimen
diuretics
  • 511 views
  • 01 May, 2021
  • 75 locations
Neoadjuvant Weekly Paclitaxel and Biomarkers of Therapy Response

The hypothesis of this study is that paclitaxel levels increase chromosomal instability (CIN) in tumors and this is lethal to tumors that have pre-existing CIN. Treatment will be administered on

biopsy of breast
cancer
metastasis
breast cancer
  • 6 views
  • 20 Feb, 2021
  • 1 location
Effect of Intravenous Acetadote on Incidence of Contrast Induced Nephropathy

In patients undergoing coronary angiography, the incidence of contrast induced nephropathy(CIN)varies widely and ranges from

cystatin c
treatment regimen
renal failure
dialysis
acetylcysteine
  • 20 views
  • 08 Nov, 2020
  • 1 location
Efficacy and Safety of Cetuximab in Combination With Cisplatin Gemcitabine as First-Line Therapy in Advanced NSCLC

Lung cancer is the leading cause of cancer deaths worldwide. It is estimated that, in 2004, 173,700 new cases of lung cancer will be diagnosed in the United States alone and 164,440 deaths due to this disease will occur(13) . NSCLC accounts for approximately 80% of all lung cancers. Among …

metastasis
pleural effusion
measurable disease
gemcitabine
ct scan
  • 3 views
  • 07 Nov, 2020
  • 1 location
Comparison of Cervical CIN II/III Treatment Outcomes With Thermal Ablation Device

cryotherapy for the treatment of cervical precancer. The investigators will investigate whether the cure rates of cervical intraepithelial neoplasia 2 and more severe diagnoses (CIN2+) with these devices are

cervical high grade squamous intraepithelial lesion
cervical intraepithelial neoplasia grade 2
cervical dysplasia
cryotherapy
cin 3
  • 0 views
  • 04 Feb, 2021
  • 3 locations