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Found 138 clinical trials
Featured trial
Use of a Non-Invasive Brainstem Neuromodulation Device to Improve Neurovascular Status in Parkinson's Disease

This study is a single-site, double-blinded, randomized clinical trial designed to elucidate mechanism(s) of action for symptomatic benefits observed in Parkinson's disease (PD)

dopamine
motor symptoms
  • 17 views
  • 06 Jun, 2022
  • 1 location
Study on Early Brain Injury Mechanism and Comprehensive Intervention of VCI

Commun in 2016 shows that the early pathological changes of AD may not be a cascade of amyloid protein (A), but a decrease in cerebral blood flow. Therefore, this project intends to establish an early

  • 21 views
  • 19 Aug, 2021
  • 1 location
Human Cerebral Blood Flow Regulation (Gas Challenge)

This study tests basic differences in how men and women control brain (cerebral) blood flow (CBF), at rest and under stress. The stress is low oxygen or high carbon dioxide. The investigators

Accepts healthy volunteers
  • 4 views
  • 23 Apr, 2022
  • 1 location
Effects of Acute Exercise Intensity on Cerebral Blood Flow and Cognitive Function in Older Adults

This study will analyze the influence of acute bout exercise intensities (continuous moderate and HIIT) on middle cerebral artery velocity (MCAv) to identify which intensity elicits the greatest increase in CBF in older adults (65+ yrs). Additionally, this study will help verify positive correlations between MCAv and cognitive function. These …

Accepts healthy volunteers
  • 0 views
  • 15 Jun, 2022
Comparing Between CO2 and Phenylephrine Treatment in Patients With Progressive Lacunar Infarction (CARBOGEN Study)

concentration of CO2 is correlated with cerebral blood flow. Lacunar infarction is small and perfused with marginal flow by neighboring perforating arteriole. Increased cerebral blood flow

  • 0 views
  • 29 May, 2021
  • 1 location
Questionnaire and Projective Color Association in Physiological Responses to Different Emotional Charge (PARC)

A sample of 101 individuals will be used for this purpose, where each of them will be exposed to 145 different stimuli. Comparison of their physiological responses to stimuli (cerebral blood

Accepts healthy volunteers
  • 0 views
  • 06 Jun, 2022
  • 1 location
Inspiratory Muscle Training in Difficult to Wean Patients

cerebral blood flow, thereby predisposing the brain to dysfunction. Restriction in brain perfusion could have an adverse impact on the function of the respiratory muscles by impairing the output of the

inspiratory muscle training
mechanical ventilation
weakness
  • 4 views
  • 12 Feb, 2022
  • 1 location
International Trial of Efficacy of Cytoflavin in Head Trauma

> Cytoflavin (Inosine + Nicotinamide + Riboflavin + Succinic Acid) is a combination drug, which improves cerebral blood flow, activates metabolic processes in the central nervous system, restores impaired

  • 2 views
  • 28 Aug, 2021
  • 2 locations
Reducing African Americans' Alzheimer's Disease Risk Through Exercise (RAATE)" (RAATE)

physiological parameters. The primary endpoints for the study are episodic memory and executive functioning. The secondary outcomes include anthropometry, blood pressure, brain activation, cerebral blood flow

mental state examination
mini-mental state examination
Accepts healthy volunteers
  • 0 views
  • 11 Mar, 2022
  • 1 location
Head-of-Bed Positioning in Large Artery Acute Ischemic Stroke

outcome. Positioning with the head of bed (HOB) at 0-degree has been shown in small studies to increase cerebral blood flow across arterial occlusion in hyperacute large artery IS, leading to clinical

  • 0 views
  • 17 Oct, 2021
  • 2 locations